Results 201 to 210 of about 85,596 (242)

Targeting Eosinophils in Eosinophilic Granulomatosis with Polyangiitis

New England Journal of Medicine, 2017
Eosinophilic granulomatosis with polyangiitis, first described in the early 1950s by Dr. Jacob Churg and Dr. Lotte Strauss (hence the original name, the Churg–Strauss syndrome), is a rare condition that can affect many organ systems, most commonly the lung, with the majority of patients presenting with asthma symptoms, occasionally complicated by the ...
Djukanović, Ratko, O'Byrne, Paul
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The eosinophil and the eye

Allergy, 1997
Personal studies in allergic eye diseases reviewed in this paper indicate that: 1. An increased number and an abnormal distribution of eosinophils is present in conjunctival biopsies of patients with vernal keratoconjunctivitis (VKC). 2. Eosinophil and eosinophil products, such as ECP, are also increased in tears of VKC patients and, in hay fever ...
BONINI, Sergio, MAGRINI L, ROTIROTI G, LAMBIASE A, TOMASSINI M, RUMI C, BONINI S.   +6 more
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Eosinophilic gastroenteritis

Current Gastroenterology Reports, 2002
Eosinophilic gastroenteritis is a rare gastrointestinal (GI) disorder of undetermined cause characterized by infiltration of eosinophils in the GI tract. Eosinophils accumulate in tissues and may release highly cytotoxic granular proteins, which cause severe tissue damage characteristic of eosinophilic gastroenteritis.
Nicholas J. Talley, Rahim Daneshjoo
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Eosinophils

2014
In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max Schultze redefined the coarsely granular cells as a type distinct from finely granular cells, rather than just a developmental stage.
Susanne Radonjic-Hösli, Hans-Uwe Simon
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Eosinophilic esophagitis: A subset of eosinophilic gastroenteritis

Current Gastroenterology Reports, 1999
Eosinophilic gastroenteritis (EG) was first described over 50 years ago. Despite its long history, it remains an ill-defined and poorly understood entity. EG can present in a number of ways, none of which are exclusive to the disorder. EG has features of allergy and immune dysregulation but does not clearly fit into the category of allergic or immune ...
Chris A. Liacouras, Jonathan E. Markowitz   +1 more
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Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis

New England Journal of Medicine
Benralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.In a phase 3, multicenter, double-blind, randomized, placebo-controlled trial, we assigned patients 12 to 65 years of age with symptomatic and histologically active ...
Marc E Rothenberg 1, Evan S Dellon 1, Margaret H Collins 1, Albert J Bredenoord 1, Ikuo Hirano 1, Kathryn A Peterson 1, Laura Brooks 1, Julie M Caldwell 1, Harald Fjällbrant 1, Hanna Grindebacke 1, Calvin N Ho 1, Matthew Keith 1, Christopher McCrae 1, Dominic Sinibaldi 1, Wendy I White 1, Catherine J Datto 1, MESSINA Trial Investigators: Fabio Almerigogna, Ignacio Antepara Ercoreca, Ana María Alonso Llamazares, Laurent Alric, Dhandapani Ashok, Kevin Bax, Lindsey McLeish, María Basagaña Torrentó, Amir Ben Tov, Adi Anafy, Dmitry S Bordin, Elen R Valitova, Albert J Bredenoord, M Laura Haasnoot, Aaltje Lei, Marco Caminati, Mirna Chehade, Constanza Ciriza de Los Ríos, Steven Clayton, Anca Mihaela Safta, Prerana Williamson, Elżbieta Czkwianianc, Wit Danilkiewicz, Nicola De Bortoli, Santino Marchi, Evan Dellon, Anjan Dhar, Rafael Firszt, Natalia Filipof, Ronald Fogel, Yasuhiro Fujiwara, Beata Gawdis-Wojnarska, Maciej Gonciarz, Nirmala Gonsalves, Frédéric Gottrand, Matthieu Antoine, Ian M Gralnek, Matthieu Groh, Catherine Nizou, Mar Guilarte Clavero, Laura Company-Sapiña, Ingrid Johana Gil, Paula Galván-Blasco, Thirumazhisai Gunasekaran, Jamal Hayat, Samantha Baillie, Attah Ocholi, Abigail Seward, Enrico Heffler, Alessandro Repici, Gaia Pellegatta, Francesca Racca, Navneet Hundal, Norihisa Ishimura, Eiko Okimoto, Anand S Jain, Halley Fowler, Maria Janiak, Jayaprakash Kamath, Showkat Hossain, Sergey Kashin, Jun Kato, Sibylle Koletzko, Hannes Leon, Tobias Schwerd, Bartosz Korczowski, Michał Korczowski, Natalya Krasnopeeva, Santhosh Kumar, Guillaume Lefevre, Jaroslaw Leszczyszyn, John Leung, Evan Cunningham, Joel Liem, Lindsay Douglas, Tracey Bondy, Delina Copland, Amanda Vieira, Maxime Luu, Kristle Lee Lynch, Jonathan Matz, François Mion, Sabine Roman, Ziva Mrevlje-Roman, Zdenka Cipinova, Rosa Muñoz-Cano, Gemma Lopez, Jason Ohayon, Sibgha Rehman, Vaidehi Bhatt, Gurnoor Walia, Robert Pesek, Erin Thomas, Safin Attwal, Kathryn Peterson, Amy Holman, Mohammed Mannan, Anupama Ravi, Imad Absah, Puanani Hopson, Yehuda Ringel, Marc Rothenberg, Kara Kliewer, Cristin Murray Petzold, Vincent Mukkada, Phil Putnam, Scott Bolton, Justin Schwartz, Pablo Abonia, Erinn Kellner, Ashley Devonshire, Frederick Ruthardt, Cecilio Santander Vaquero, Sergio Casabona Francés, Teresa Pérez Fernandez, Verónica Martin Domínguez, Pedro Majano Rodriguez, Francisca Molina Jiménez, Jennifer Fernandez Pacheco, Ellen Sher, Gary Gross, Jacqueline Ross, Ulyana Trytko, Peter Siersema, Dareen Siri, María Luisa Somoza Álvarez, Kathrin Sprinzl, Anna Stanziola, Miguel Stein, Robert Szalewski, Vinay Mehta, Alexander Trukhmanov, Vladimir Ivashkin, Tatiana Lapina, Toshio Uraoka, Christoph Schlag, Simon Weidlich, Jörg Ulrich, Bas Weusten, Phillip Woodland, William Yang, Patrizia Zentilin, Manuele Furnari, Elisabetta Giuliana, Giorgia Bodini, Elisa Marabotto, Frank Zerbib, Noam Zevit, Maciej Żymła   +164 more
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Eosinophilic Cationic Protein in Chronic Eosinophilic Pneumonia and Eosinophilic Granuloma

Chest, 1994
We measured eosinophilic cationic protein (ECP) concentrations in the circulation and bronchoalveolar lavage (BAL) fluids from patients with chronic eosinophilic pneumonia, patients with eosinophilic granuloma, and normal control subjects. Significantly increased ECP concentrations were found in the circulation of patients with chronic eosinophilic ...
Noriharu Shijubo, Michio Hirasawa, Shosaku Abe, Manabu Inuzuka, Katsunori Shigehara   +4 more
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Eosinophilic Enteritis

Digestive Diseases, 2015
<b><i>Background:</i></b> Eosinophilic enteritis, also known as eosinophilic gastroenteritis, is a rare primary eosinophilic gastrointestinal disorder (EGID) of unknown etiology characterized by the presence of an intense eosinophilic infiltrate on histopathology of the intestinal mucosa. <b><i>Key Messages:</i>
Pineton de Chambrun, Guillaume, Desreumaux, P., Cortot, Antoine   +2 more
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Heterogeneity of Eosinophils in Chronic Eosinophilic Pneumonia

International Archives of Allergy and Immunology, 1996
It has previously been shown that patients with chronic eosinophilic pneumonia can be divided into 2 groups according to the chemotactic response of their eosinophils to 5 different eosinophil chemotactic factors (ECFs) and laboratory findings. In contrast, eosinophils obtained by bronchoalveolar lavage from both groups responded to all 5 ECFs.
Hirotsugu Kohrogi, Mineharu Sugimoto, Tohru Yamanaka, Mitsuomi Hirashima, Moritaka Suga, Masayuki Ando, Naoki Saita   +6 more
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Eosinophilic cellulitis and eosinophilic pustular folliculitis

Journal of the American Academy of Dermatology, 1989
This report describes a patient with a drug reaction and histologic changes of both eosinophilic cellulitis and eosinophilic pustular folliculitis. We propose that some cases of eosinophilic pustular folliculitis, like eosinophilic cellulitis, may occur as a result of a hypersensitivity phenomenon.
Wilma F. Bergfeld, Judith M. Andreano, Ralph J. Tuthill, James S. Taylor, Gary R. Kantor   +4 more
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