Results 271 to 280 of about 88,328 (315)
Eosinophilic Gastroenteritis or Eosinophilic Chloroma? [PDF]
Acta Haematologica, 2004 Granulocytic sarcoma of the small intestine preceding or as the presenting feature of acute myelogenous leukemia with chromosome 16 abnormalities has been observed in at least 4 patients. We report the case of a patient initially diagnosed with eosinophilic gastroenteritis, responding to corticosteroid treatment for 21 months and eventually ...
J.F. Nomdedeu, A. Julia
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Annual Review of Immunology, 2006
Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this perspective by showing that eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators of innate and ...
Marc E, Rothenberg, Simon P, Hogan
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Eosinophils have been considered end-stage cells involved in host protection against parasites. However, numerous lines of evidence have now changed this perspective by showing that eosinophils are pleiotropic multifunctional leukocytes involved in initiation and propagation of diverse inflammatory responses, as well as modulators of innate and ...
Marc E, Rothenberg, Simon P, Hogan
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Eosinophilic myocarditis [PDF]
Herz, 2012 Eosinophilic myocarditis is caused by activation of eosinophilic granulocytes whereby there is a release of eosinophilic granules. Quite a few of the released compounds, especially eosinophilic cationic proteins, have a tissue-damaging effect also in the myocardium. Eosinophilia may be due to hypersensitivity, parasitic infection etc.
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To be, or not to be, an eosinophil: that is the ??? [PDF]
Blood, 2013 In this issue of Blood, Doyle et al provide evidence that knockout of the genes encoding the two most abundant eosinophil secondary granule proteins disrupts the normal differentiation of eosinophils from progenitors in the bone marrow, providing a novel strain of mice with a highly specific deficiency in eosinophilopoiesis and, therefore, eosinophils.
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Annals of Internal Medicine, 2003
Eosinophilic esophagitis is a new disease commonly confused with gastroesophageal reflux disease. Because of different treatments, recognition of eosinophilic esophagitis is important.Recent work further characterizes the allergic response, demonstrating a population of eosinophils different from gut and blood that specifically homes to the esophagus ...
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Eosinophilic esophagitis is a new disease commonly confused with gastroesophageal reflux disease. Because of different treatments, recognition of eosinophilic esophagitis is important.Recent work further characterizes the allergic response, demonstrating a population of eosinophils different from gut and blood that specifically homes to the esophagus ...
openaire +6 more sources
Targeting Eosinophils in Eosinophilic Granulomatosis with Polyangiitis
New England Journal of Medicine, 2017Eosinophilic granulomatosis with polyangiitis, first described in the early 1950s by Dr. Jacob Churg and Dr. Lotte Strauss (hence the original name, the Churg–Strauss syndrome), is a rare condition that can affect many organ systems, most commonly the lung, with the majority of patients presenting with asthma symptoms, occasionally complicated by the ...
Djukanović, Ratko, O'Byrne, Paul
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Allergy, 1997
Personal studies in allergic eye diseases reviewed in this paper indicate that: 1. An increased number and an abnormal distribution of eosinophils is present in conjunctival biopsies of patients with vernal keratoconjunctivitis (VKC). 2. Eosinophil and eosinophil products, such as ECP, are also increased in tears of VKC patients and, in hay fever ...
BONINI, Sergio +6 more
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Personal studies in allergic eye diseases reviewed in this paper indicate that: 1. An increased number and an abnormal distribution of eosinophils is present in conjunctival biopsies of patients with vernal keratoconjunctivitis (VKC). 2. Eosinophil and eosinophil products, such as ECP, are also increased in tears of VKC patients and, in hay fever ...
BONINI, Sergio +6 more
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Current Gastroenterology Reports, 2002
Eosinophilic gastroenteritis is a rare gastrointestinal (GI) disorder of undetermined cause characterized by infiltration of eosinophils in the GI tract. Eosinophils accumulate in tissues and may release highly cytotoxic granular proteins, which cause severe tissue damage characteristic of eosinophilic gastroenteritis.
Nicholas J. Talley, Rahim Daneshjoo
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Eosinophilic gastroenteritis is a rare gastrointestinal (GI) disorder of undetermined cause characterized by infiltration of eosinophils in the GI tract. Eosinophils accumulate in tissues and may release highly cytotoxic granular proteins, which cause severe tissue damage characteristic of eosinophilic gastroenteritis.
Nicholas J. Talley, Rahim Daneshjoo
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2014
In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max Schultze redefined the coarsely granular cells as a type distinct from finely granular cells, rather than just a developmental stage.
Susanne Radonjic-Hösli, Hans-Uwe Simon
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In 1846, T. Wharton-Jones described a coarsely granular stage in the development of granulocytic cells in animal and human blood. Shortly thereafter, Max Schultze redefined the coarsely granular cells as a type distinct from finely granular cells, rather than just a developmental stage.
Susanne Radonjic-Hösli, Hans-Uwe Simon
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Eosinophil Depletion with Benralizumab for Eosinophilic Esophagitis
New England Journal of MedicineBenralizumab is an eosinophil-depleting anti-interleukin-5 receptor α monoclonal antibody. The efficacy and safety of benralizumab in patients with eosinophilic esophagitis are unclear.In a phase 3, multicenter, double-blind, randomized, placebo-controlled trial, we assigned patients 12 to 65 years of age with symptomatic and histologically active ...
Marc E Rothenberg 1 +164 more
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