Results 71 to 80 of about 95,376 (339)

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, Accepted Article.
Objectives Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The Phase III MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E Wechsler, Jared Silver, Gerhard Wolff, Robert G Price, Rejina Verghis, Peter F Weller, Peter A Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

Diagnostic accuracy of blood eosinophils in comparison to other common biomarkers for identifying sputum eosinophilia in patients with chronic cough

World Allergy Organization Journal, 2023
Background: Sputum eosinophilia is a treatable trait for chronic cough. It is currently not clear whether the blood eosinophil counts could be used to identify sputum eosinophilia in patients with chronic cough.
Fang Yi, MD, PhD, Zhangfu Fang, MD, PhD, Hanwen Liang, MD, Lianrong Huang, MD, Mei Jiang, MD, PhD, Zien Feng, MD, Keheng Xiang, MD, Zhe Chen, MD, PhD, Wei Luo, MSc, Kefang Lai, MD, PhD   +9 more
doaj  

The relationship between eosinophilia and bronchopulmonary dysplasia in premature infants at less than 34 weeks' gestation [PDF]

Korean Journal of Pediatrics, 2014
PurposeEosinophilia is common in premature infants, and its incidence increases with a shorter gestation period. We investigated the clinical significance of eosinophilia in premature infants born at
Joo Yun Yang, Jihei Cha, So-Yeon Shim, Su Jin Cho, Eun Ae Park   +4 more
doaj   +1 more source

Acute Facial Edema in a Patient with Systemic Lupus Erythematosus

Reports, 2021
Allergies have been found to be associated with systemic lupus erythematosus (SLE). However, few reports have described angioedema occurring in elderly men with systemic lupus erythematosus.
Shiho Amano, Ryuichi Ohta, Chiaki Sano
doaj   +1 more source

Safety of sulfamethoxazole–trimethoprim for the treatment of bacterial infection in outpatient settings: A systematic review and meta‐analysis with active comparator disproportionality analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims Sulfamethoxazole–trimethoprim (SMX‐TMP) is a widely used antibiotic for treating bacterial infections, but its safety in adult outpatients remains understudied. This systematic review and meta‐analysis evaluated the safety profile of SMX‐TMP and identified critical research gaps.
Rebecca Preyra, Lujain Ez Eddin, Fatemeh Ahmadi, Atefeh Jafari, Flory T. Muanda   +4 more
wiley   +1 more source

The diagnostic difficulties of eosinophilia in clinical practice - case series

Journal of Education, Health and Sport, 2019
Introduction: Eosinophilia, defined as elevated level of eosinophils in peripheral blood above 5 x 109/L, is the hematological disorder, which may occur in multiple conditions, such as allergies, gastrointestinal, autoimmune diseases, parasite, fungal ...
Agnieszka Szymczyk, Magdalena Szydełko, Joanna Szydełko, Jakub Jaworski, Yuliya Onyshchuk, Rafał Dziedzic, Marek Hus, Monika Podhorecka   +7 more
doaj   +3 more sources

Peripheral Eosinophilia and Clinico-radiological Characteristics among Health Screening Program Recipients

Tuberculosis and Respiratory Diseases, 2018
Background Eosinophilia is well recognized in specific conditions. The objective of the present study was to determine clinico-radiologic characteristics of eosinophilia and changes in prevalence over 10 years in recipients of private health screening
Tae Yun Park, M.D., Jae-Woo Jung, M.D., Ph.D., Ju Young Jang, M.D., Ph.D., Jae Chol Choi, M.D., Ph.D., Jong Wook Shin, M.D., Ph.D.,, In Won Park, M.D., Ph.D., Byoung Whui Choi, M.D., Ph.D. , Jae Yeol Kim, M.D., Ph.D.   +7 more
doaj  

The efficacy of step‐down therapy in adult patients with proton pump inhibitor‐responsive oesophageal eosinophilia

Alimentary Pharmacology and Therapeutics, 2016
Proton pump inhibitor‐responsive oesophageal eosinophilia (PPI‐REE) is common in patients with suspected eosinophilic oesophagitis (EoE). However, the long‐term efficacy of PPIs and the best maintenance doses are yet to be defined.
E. Gómez-Torrijos, R. García-Rodríguez, A. Castro-Jiménez, J. Rodríguez-Sánchez, Y. M. Díaz, J. Molina-Infante   +5 more
semanticscholar   +1 more source

Gleich syndrome and eosinophilic fasciitis overlap successfully treated with mepolizumab

, 2022
The Journal of Dermatology, Volume 49, Issue 12, Page 1348-1350, December 2022.
Thilo Gambichler, Christian Chmelar, Stathis Philippou, Rolf M. Szeimies, Maria Chatzipantazi   +4 more
wiley   +1 more source

Endomyocardial involvement in asymptomatic sub-Saharan immigrants with helminth-related eosinophilia. [PDF]

PLoS Neglected Tropical Diseases, 2017
BACKGROUND:Among immigrants of sub-Saharan origin, parasitic infection is the leading cause of eosinophilia, which is generally interpreted as a defense mechanism.
Cristina Carranza-Rodríguez, Daniel San-Román-Sánchez, Héctor Marrero-Santiago, Michele Hernández-Cabrera, Carlos Gil-Guillén, Elena Pisos-Álamo, Nieves Jaén-Sánchez, José-Luis Pérez-Arellano   +7 more
doaj   +1 more source