Results 71 to 80 of about 90,479 (297)

Long‐Term Safety and Efficacy of Mepolizumab in Eosinophilic Granulomatosis With Polyangiitis

Arthritis &Rheumatology, EarlyView.
Objective Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare, relapsing, inflammatory disease. Management of EGPA predominantly relies on oral corticosteroids (OCS), which are associated with many adverse effects. The phase 3 MIRRA trial demonstrated efficacy and safety of mepolizumab, anti‐interleukin‐5 biologic, for EGPA.
Michael E. Wechsler, Jared Silver, Gerhard Wolff, Robert G. Price, Rejina Verghis, Peter F. Weller, Peter A. Merkel, Paneez Khoury, on behalf of the EGPA Mepolizumab Open‐Label Extension study group, Arnaud Bourdin, Pascal Chanez, Anoop Chauhan, Vincent Cottin, Gerald Gleich, Berhnard Hellmich, Tomonori Ishii, David Jayne, Jean‐Emmanuel Kahn, Peter Kern, Nader Khalidi, Ina Koetter, Carol Langford, Amy Markezich, Paul Monach, Shamsa Naveed, Peter Oelzner, Kenneth Pinna, Xavier Puechal, Emory H. Robinette, Florence Roufosse, Reinhard Voll, Andrew Schafer, Kaharu Sumino, Masami Taniguchi, Phillip Lieberman   +34 more
wiley   +1 more source

A report of an unusual case of pediatric eosinophilia associated with platelet-derived growth factor receptor-beta rearrangement

Indian Journal of Medical and Paediatric Oncology, 2020
Eosinophilia is a common finding in the pediatric age group. While the majority of mild eosinophilia cases are benign and due to reactive causes, persistent hypereosinophilia is uncommon and requires prompt clinical evaluation because of the potential ...
Abdul Wajid Moothedath, Debasish Sahoo, Rachna Seth, Jagdish Prasad Meena, Aditya Kumar Gupta   +4 more
doaj   +1 more source

An unusual presentation of a case of human psittacosis [PDF]

, 2018
Background: Chlamydia psittaci is a gram-negative, obligate intracellular organism. Birds are the main reservoir, but also non-avian domestic animals and humans can be infected.
Boelens, Jerina, De Spiegeleer, Anton, Thijs, Elke, Van Braeckel, Eva, Vande Weygaerde, Yannick, Vanrompay, Daisy, Vermaelen, Karim, Versteele, Charlot   +7 more
core   +3 more sources

Strongyloides stercoralis: The Most Prevalent Parasitic Cause of Eosinophilia in Gilan Province, Northern Iran [PDF]

Iranian Journal of Parasitology, 2010
Background: Eosinophilia occurs in a wide variety of situations such as parasitic infections, aller­gic disorders, and malignancies. Most cases of eosinophilia of parasitic origin, especially those with a tissue migration life cycles consists of human ...
K Ashrafi, A Tahbaz, B Rahmati
doaj   +1 more source

Successful treatment of eosinophilia associated with dialysis‐related renal cancer with radical nephrectomy

IJU Case Reports
Introduction Secondary eosinophilia due to solid tumors is a rare case. This is the first study to report secondary eosinophilia due to renal cancer in a patient on dialysis. Case presentation A 70‐year‐old man, on long‐term hemodialysis was incidentally
Yuta Goto, Daichi Tamura, Tomohiko Matsuura, Ei Shiomi, Daiki Ikarashi, Shigekatsu Maekawa, Renpei Kato, Mitsugu Kanehira, Wataru Obara   +8 more
doaj   +1 more source

Frequency of PDGFRA, PDGFRB and FGFR1 Gene Rearrangements in Patients with Eosinophilia and Their Clinico-Haematologic Parameters

Pakistan Armed Forces Medical Journal, 2023
Objective: To determine the frequency and clinico-haematological features of PDGFRA, PDGFRB and FGFR1 gene rearrangements in patients with persistent Eosinophilia using Fluorescence in situ hybridization. Study Design: Cross-sectional study. Place
Saniya Jalil, Helen Mary Robert, Hamid Saeed, Asad Mehmood Abbasi, Aamna Latif, Annum Sardar   +5 more
doaj   +1 more source

Interleukin-4 activated macrophages mediate immunity to filarial helminth infection by sustaining CCR3-dependent eosinophilia

PLoS Pathogens, 2018
Eosinophils are effectors in immunity to tissue helminths but also induce allergic immunopathology. Mechanisms of eosinophilia in non-mucosal tissues during infection remain unresolved.
J. Turner, N. Pionnier, Julio Furlong-Silva, H. Sjoberg, Stephen Cross, A. Halliday, Ana F Guimaraes, Darren Cook, A. Steven, N. Van Rooijen, J. Allen, S. Jenkins, M. Taylor   +12 more
semanticscholar   +1 more source

Expert Perspective: Diagnosis and Treatment of Castleman Disease

Arthritis &Rheumatology, Accepted Article.
Summary Castleman disease (CD) is a major diagnostic challenge for Rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y.C. Chen, Lu Zhang, David C. Fajgenbaum   +2 more
wiley   +1 more source

Eosinophilia in Very Low Birth Weight Infants

Pediatrics and Neonatology, 2010
Eosinophilia is common in premature infants, though its clinical significance remains unknown. This study investigated the pattern of eosinophilia and related factors in very low birth-weight (VLBW) infants.
Jui-Mei Yen, Chyi-Her Lin, Mei-Mei Yang, Shih-Ting Hou, Ai-Hsi Lin, Yuh-Jyh Lin   +5 more
doaj   +1 more source

Cutaneous adverse drug reactions in patients with peripheral blood eosinophilia during antituberculosis treatment [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims Peripheral eosinophilia during tuberculosis (TB) treatment is common, but has not been fully evaluated. The aim of this study was to determine the prevalence and clinical significance of peripheral blood eosinophilia in patients ...
Tae-Ok Kim, Hong-Joon Shin, Yu-Il Kim, Sung-Chul Lim, Young-Il Koh, Yong-Soo Kwon   +5 more
doaj   +1 more source