Results 71 to 80 of about 115,914 (189)

Eosinophilic Gastroenteritis in the Setting of Colorectal Neoplasia

World Journal of Colorectal Surgery, 2020
Eosinophilic gastroenteritis is a rare inflammatory disease of one or more segments of the gastrointestinal tract. Clinical features vary depending on the site and layer of involvement.
Yi Sien Koo, June Oo, Suat Chin Ng
doaj   +1 more source

The Psoriasis–Eczema Interface: Clinical Classification and Therapeutic Implications From a Bicentric Experience

International Journal of Dermatology, EarlyView.
The psoriasis–atopic dermatitis interface: four clinical phenotypes (coexisting, overlapping, biologic‐induced eczema, dupilumab‐induced psoriasis) across 105 patients from two Italian tertiary centers. JAK inhibitors achieved the highest response rates across all phenotypes, reflecting their mechanistic rationale targeting shared JAK‐STAT downstream ...
Michela D'Agostino, Gennaro Marco Falco, Eleonora De Luca, Clara De Simone, Alessandro Di Stefani, Maddalena Napolitano, Ketty Peris, Matteo Megna, Giacomo Caldarola   +8 more
wiley   +1 more source

Interleukin‐12: Central Roles in Immune Regulation and Disease Therapy

Immunology &Cell Biology, EarlyView.
IL‐12 levels are tightly regulated to balance effective protective immunity against infections and cancer with the risk of excessive inflammation and autoimmune disease. Both insufficient and excessive IL‐12 activity can therefore be detrimental, highlighting the importance of precisely controlling its production and signaling. ABSTRACT Interleukin‐12 (
Anthi Psoma, Geert van den Bogaart
wiley   +1 more source

Microscopic colitis: Current status, present and future challenges Statements of the European Microscopic Colitis Group [PDF]

, 2012
Microscopic colitis (MC) is an inflammatory bowel disease presenting with chronic, non-bloody watery diarrhoea and few or no endoscopic abnormalities.
Bonderup, Ole Kristian, Hjortswang, H., Miehlke, S., Ström, M, Hjortswang, H.,, Aust, D., Münch, A., Fernández Bañares, F, Munck, L K, Tysk, C.,, Bonderup, O.,, Bohr, Johan,, Hjortswang, H, Münch, A.,, Tysk, C., Madisch, A.,, Bañares, F. Fernández,, Bonderup, O., Münch, A, Miehlke, S, Aust, D.,, Madisch, A., Aust, D, Ström, M.,, Hjortswang, Henrik,, Ström, M., Madisch, A, Miehlke, S.,, Fernandez Banares, F.,, Munck, L.K., Bohr, J.,, Ström, Magnus,, Munck, L. K.,, Bohr, Jakob, Münch, Andreas,, Tysk, Curt,, Tysk, C, Bohr, J., Fernández Bañares, F.   +38 more
core   +1 more source

Tissue Resident Memory Cells: Friend or Foe?

Immunology, EarlyView.
Tissue‐resident memory T cells (TRM cells) are specialised immune cells in barrier tissues like the lungs, skin and gut, providing rapid host defence and tumour surveillance. Their retention and differentiation are regulated by molecules such as CD69, CD103 and TGF‐β. Dysregulation of TRM cells can lead to chronic activation, driving conditions such as
Chidimma F. Chude, Jude E. Uzonna, Janilyn Arsenio   +2 more
wiley   +1 more source

Multiorgan eosinophilic infiltration after initiation of clozapine therapy: a case report

BMC Research Notes, 2017
Background The eosinophilic response to clozapine is well described in the literature, causing a variety of responses, from serositis to colitis.
Dorota Marchel, Anita L. Hart, Patricia Keefer, Jennifer Vredeveld   +3 more
doaj   +1 more source

The Role of Innate Lymphoid Cells in Autoimmune, Allergic and Infectious Diseases: A Systematic Review

Immunology, EarlyView.
This systematic review establishes disease‐specific dysregulations of human innate lymphoid cells (ILCs), demonstrating that an ILC1/ILC3 imbalance compromises mucosal barriers in inflammatory bowel disease, while activated ILC2s drive allergic airway inflammation.
Luan F. Lückmann, Henrique R. Dal‐Pizzol, Louise M. Lückmann, Davi E. Salini, Bruna C. Hasckel, Mikaeli Minati, Bruno Kluwe‐Schiavon, Tatiana Barichello   +7 more
wiley   +1 more source

Eosinophilic Colitis Presenting with Chronic Diarrhea [PDF]

, 2018
Eosinophilic colitis (EC) is a rare disease which characterized by infiltration of eosinophil in colon and peripheral eosinophilia. Other causes of peripheral eosinophilia need to be excluded before assumed EC such as food allergy, inflammatory bowel ...
Setijoso, Rafael Eddy, Renaningtyas Tambun, Tambun, Renaningtyas, Hendra Koncoro, Rafael Eddy Setijoso, Koncoro, Hendra   +5 more
core   +1 more source

Eosinophilic disorders of the gastrointestinal tract: clinical manifestations, diagnosis and treatment

Alʹmanah Kliničeskoj Mediciny, 2018
Eosinophilic gastrointestinal disorders (EGID) are a kind of pathology which has not been well studied and has a trend to an increase during the last years that raises concern.
E. A. Kornienko, Yu. A. Moiseenkova, N. L. Volkova, T. B. Loboda   +3 more
doaj   +1 more source

Plasma ADAMTS13 activity in healthy dogs and dogs with chronic enteropathy

Journal of Small Animal Practice, EarlyView.
Objectives A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 is a von Willebrand factor cleaving enzyme that is associated with prothrombotic/hypercoagulable states in humans. In people, A disintegrin and metalloproteinase with thrombospondin type 1 motif, member 13 activity is reduced with inflammatory bowel disease ...
S. I. Barth, S. M. DeMonaco, B. J. Conner, P. B. S. Serpa, A. R. Wilkinson   +4 more
wiley   +1 more source