Results 141 to 150 of about 5,887,855 (243)
Eosinophilic Oesophagitis and Incidence of Gastrointestinal Cancer: A Population‐Based Cohort Study
Alimentary Pharmacology &Therapeutics, EarlyView.Among 9115 patients with eosinophilic oesophagitis in Denmark, excess gastrointestinal cancer in the first year after diagnosis most likely reflected diagnostic work‐up. Beyond 1 year, oesophageal adenocarcinoma and hepatocellular carcinoma remained more frequent than expected; most patients with oesophageal cancer had prior Barrett's oesophagus ...
Gencer Kurt +4 more
wiley +1 more source
Local Delivery of a Bio‐Engineered IL‐37 Fc‐Fusion Ameliorates Experimental Allergic Asthma in Mice
Allergy, EarlyView.
Lars P. Lunding +3 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Cancer Science, EarlyView.Targeted triggering of SORL1 expression through a novel MPOC delivery system could inhibit ccRCC progression through binding to TRIM22 and further promoting ubiquitination‐mediated C‐MYC degradation, thereby facilitating the inhibition of oxidative phosphorylation through transcriptional repression of ACO2 and IDH2.
Keyi Wang +11 more
wiley +1 more source
Cancer Science, EarlyView.hTROP2 Tg rats exhibit key pathological and transcriptomic features of DXd ADC‐related ILD, supporting their utility as a translational model. Rat, alveolus, antibody illustrations were adapted from NIAID NIH BioArt Source. ABSTRACT Deruxtecan‐based antibody‐drug conjugates (DXd ADCs) provide substantial clinical benefit across multiple malignancies ...
Kazuyoshi Kumagai +5 more
wiley +1 more source
Rapid Onset of Mesalazine-Induced Eosinophilic Pneumonia Manifesting 7 Days After Initiation: A Case Report. [PDF]
Respirol Case RepInazaki T +12 more
europepmc +1 more source
Dynamic Gut-Lung Microbiome Interactions Beyond Dysbiosis Across the Course of COPD. [PDF]
Int J Chron Obstruct Pulmon DisRen Y, Hu Y, Qin H, Zhang Y, Zhao H.
europepmc +1 more source
15-hydroxyeicosatetraenoic acid (15-HETE)-GPR39 axis: a potential therapeutic target in eosinophilic asthma. [PDF]
Front PharmacolEngel A, Nie Z, Kaul S.
europepmc +1 more source