Results 121 to 130 of about 5,887,855 (243)

Eosinophils in chronic obstructive pulmonary disease

Therapeutic Advances in Respiratory Disease
Chronic Obstructive Pulmonary Disease (COPD) is a heterogeneous lung condition characterised by chronic respiratory symptoms, fixed airway obstruction and persistent inflammation that leads to a progressive airflow limitation.
Marco Vanetti, Dina Visca, Francesco Ardesi, Martina Zappa, Patrizia Pignatti, Antonio Spanevello   +5 more
doaj   +1 more source

Nematode in Cockroaches: A Potential Allergen Source

Allergy, EarlyView.
Dongjun Kang, Myung‐hee Yi, Jun Ho Choi, Yun Soo Jang, Seongjun Choe, Ju Yeong Kim   +5 more
wiley   +1 more source

Factors for Success and Failure of Allergen Immunotherapy (AIT) Trial Design in the Light of Evidence‐Based Medicine: Current Aspects 2026

Allergy, EarlyView.
ABSTRACT Allergen immunotherapy (AIT) has been acknowledged as the only disease‐modifying treatment for respiratory diseases since its introduction in 1911. Although the efficacy and safety have convincingly been established in numerous randomized clinical trials (RCTs), the AIT study results may vary substantially.
Roy Gerth van Wijk, Vera Mahler, Melanie Albrecht, Danilo di Bona, Benjamin Hofner, Jasper Kappen, Susanne Kaul, Graham Roberts, Mohamed H. Shamji, Stefan Vieths, Oliver Pfaar   +10 more
wiley   +1 more source

Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma

Allergy, EarlyView.
This study investigates the effect of mepolizumab on the proteomic and transcriptomic profile of blood eosinophils in SEA patients. Mepolizumab reduces the migratory capacity and effector‐related molecular signatures of circulating eosinophils in SEA patients.
Pablo Miguéns‐Suárez, Sara Vázquez‐Mera, Laura Martelo‐Vidal, Marina Blanco Aparicio, Uxío Calvo Álvarez, Coral González Fernández, Mar Mosteiro Añón, Dolores Corbacho Abelaira, Tamara Hermida Valverde, Christian Calvo Henríquez, Susana B. Bravo, Lena Uller, Juan J. Nieto‐Fontarigo, Francisco J. Salgado, Francisco J. González‐Barcala   +14 more
wiley   +1 more source

Selective Absence of Co‐Inhibitory Receptor‐Expressing CD4+ T Cells in Lungs of Obese House Dust Mite‐Allergic C57BL/6 Mice

Allergy, EarlyView.
Obesity altered the inflammatory phenotype of HDM‐induced allergic airway inflammation in C57BL/6 mice, indicated by changed BAL cell composition. Single‐cell CITE‐Seq identified the lack of a CD4+ T‐cell subcluster characterized by co‐inhibitory receptor expression in obese HDM‐exposed C57BL/6 mice.
Sarah Miethe, Daniel P. Potaczek, Kim Pauck, Andrea Berlin, Bilal Alashkar Alhamwe, Stefanie Hagner, Andrea Nist, Elke Pogge von Strandmann, Thorsten Stiewe, Paul Klemm, Hartmann Raifer, Clemens Thölken, Holger Garn   +12 more
wiley   +1 more source

Paragonimiasis Following Ingestion of Frozen Freshwater Crab: Two Case Reports

Respirology Case Reports
Paragonimiasis is a zoonotic disease caused by trematodes belonging to the genus Paragonimus. It is acquired by ingesting freshwater crustaceans or raw game meat.
Asuka Yamamura, Muneyuki Sekiya, Yusuke Usui, Susumu Sakamoto, Keiya Watanabe, Kohshi Fukuda, Yasuko Kurose, Naobumi Tochigi, Mio Kokubo, Haruhiko Maruyama, Kazuma Kishi   +10 more
doaj   +1 more source

Asthma Remission From Childhood to Young Adulthood–A Population‐Based Cohort Study

Allergy, EarlyView.
Among 257 participants with asthma at age 8 years, 39% achieved symptom‐based remission by age 24, 29% achieved clinical remission, and 18% achieved complete remission. Male sex increased the likelihood of symptom‐based remission, while food sensitization and overweight/obesity decreased the likelihood.
Lina Broström, Anna Bergström, Anne‐Sophie Merritt, Maria Ödling, Erik Melén, Inger Kull, Sandra Ekström   +6 more
wiley   +1 more source

Clinical, Biomarker, and Radiological Progression from Asthma to Systemic Eosinophilic Granulomatosis with Polyangiitis: A Retrospective Cohort Study

Journal of Asthma and Allergy
Chenyang Lu,1,* Changxing Ou,1,* Yu Deng,2,* Na Li,3,* Yuwen Ma,1 JinXi Luo,1 Jiaxuan Zhou,2 Kian Fan Chung,4 Zhenan Deng,1 Qingling Zhang1,5 1State Key Laboratory of Respiratory Disease, National Clinical Research Center ...
Lu C, Ou C, Deng Y, Li N, Ma Y, Luo J, Zhou J, Chung KF, Deng Z, Zhang Q   +9 more
doaj  

The Union and Médecins Sans Frontières approach to operational research. [PDF]

, 2011
Operational research (OR) has become a hot topic at national meetings, international conferences and donor fora. The International Union Against Tuberculosis and Lung Disease (The Union) and Médecins Sans Frontières (MSF) Operational Centre Brussels ...
Fujiwara, P I, Berger, SD, Harries, AD, Detjen, AK, Berger, S D, Harries, A D, Detjen, A K, Bissell, K, Fussell, M, Zachariah, R, Edginton, M, Rusen, ID, Hinderaker, S G, Rusen, I D, Fujiwara, PI, Reid, T, Hinderaker, SG   +16 more
core  

Decoding the “Metallic” Immune Imprint: Single‐Cell Exposomics Reveals the Immune Imprint of Fire Smoke

Allergy, EarlyView.
Takafumi Kubota, Yuki Matsumoto, Takahiro Tabuchi   +2 more
wiley   +1 more source