Results 31 to 40 of about 19,435 (196)

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways. [PDF]

PLoS ONE, 2014
BACKGROUND:Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma.
Gustavo Nino, Shehlanoor Huseni, Geovanny F Perez, Krishna Pancham, Humaira Mubeen, Aleeza Abbasi, Justin Wang, Stephen Eng, Anamaris M Colberg-Poley, Dinesh K Pillai, Mary C Rose   +10 more
doaj   +3 more sources

Gene expression profiling following NRF2 and KEAP1 siRNA knockdown in human lung fibroblasts identifies CCL11/Eotaxin-1 as a novel NRF2 regulated gene

Respiratory Research, 2012
Background Oxidative Stress contributes to the pathogenesis of many diseases. The NRF2/KEAP1 axis is a key transcriptional regulator of the anti-oxidant response in cells.
Fourtounis Jimmy, Wang I-Ming, Mathieu Marie-Claude, Claveau David, Loo Tenneille, Jackson Aimee L, Peters Mette A, Therien Alex G, Boie Yves, Crackower Michael A   +9 more
doaj   +4 more sources

Eotaxin-1/CCL11 is involved in cell migration in rheumatoid arthritis. [PDF]

Sci Rep, 2021
AbstractEotaxin-1 (CCL11) induces the migration of different leukocyte types by interacting with CCR3. In rheumatoid arthritis (RA), fibroblast-like synoviocytes (FLS) are pathogenic effectors and a major CCR3-expressing cell. The aim of this study was to investigate the expression and function of CCL11 in RA FLS.
Wakabayashi K, Isozaki T, Tsubokura Y, Fukuse S, Kasama T.   +4 more
europepmc   +5 more sources

Effect of cigarette smoke on counts of immunoreactive cells to eotaxin-1 and eosinophils on the nasal mucosa in young patients with perennial allergic rhinitis

Brazilian Journal of Otorhinolaryngology, 2016
Introduction: In teenagers with perennial allergic rhinitis, exposure to tobacco cigarette smoke increases the count of eosinophils in the nasal mucosa; the recruitment of eosinophils arises from the combined action of a number of cellular and molecular ...
Bertha Beatriz Montaño-Velázquez, Eulalia Beatriz Flores-Rojas, Francisco Javier García-Vázquez, Silvio Jurado-Hernandez, Marco Antonio Venancio Hernández, Angélica Kathya Alanis Flores, Kathrine Jáuregui-Renaud   +6 more
doaj   +3 more sources

Differential regulation of CCL-11/eotaxin-1 and CXCL-8/IL-8 by Gram-positive and Gram-negative bacteria in human airway smooth muscle cells [PDF]

Respiratory Research, 2008
Background Bacterial infections are a cause of exacerbation of airway disease. Airway smooth muscle cells (ASMC) are a source of inflammatory cytokines/chemokines that may propagate local airway inflammatory responses.
Chung Kian Fan, Sriskandan Shiranee, Sukkar Maria B, Sorrentino Rosalinda, Issa Razao, Mitchell Jane A   +5 more
doaj   +4 more sources

Eotaxin-1 (CCL11) in neuroinflammatory disorders and possible role in COVID-19 neurologic complications. [PDF]

Acta Neurol Belg, 2022
The related neurologic complications of SARS-CoV-2 infection in COVID-19 patients and survivors comprise symptoms including depression, anxiety, muscle pain, dizziness, headaches, fatigue, and anosmia/hyposmia that may continue for months. Recent studies have been demonstrated that chemokines have brain-specific attraction and effects such as ...
Nazarinia D, Behzadifard M, Gholampour J, Karimi R, Gholampour M.   +4 more
europepmc   +3 more sources

Role of Eotaxin-1 Signaling in Ovarian Cancer [PDF]

Clinical Cancer Research, 2009
AbstractPurpose: Tumor cell growth and migration can be directly regulated by chemokines. In the present study, the association of CCL11 with ovarian cancer has been investigated.Experimental Design and Results: Circulating levels of CCL11 in sera of patients with ovarian cancer were significantly lower than those in healthy women or women with breast,
Levina, V, Nolen, BM, Marrangoni, AM, Cheng, P, Marks, JR, Mirosław Jerzy Szczepański, Szajnik, ME, Gorelik, E, Lokshin, AE   +8 more
openaire   +2 more sources

Synovial Fluid Eotaxin-1 Levels May Reflect Disease Progression in Primary Knee Osteoarthritis Among Elderly Han Chinese: A Cross-Sectional Study. [PDF]

Cartilage, 2019
ObjectiveThe CC chemokine family member eotaxin-1, also named chemokine C-C motif ligand 11 (CCL11), has been detected in knee osteoarthritis (OA) and could induce breakdown of cartilage matrix.
Li B, Zhang YL, Yu SY.
europepmc   +2 more sources

Eotaxin-2 and eotaxin-3 in malaria exposure and pregnancy

Malaria Journal, 2022
Background Eotaxin-1 concentrations in plasma have been inversely associated with malaria exposure, malaria infection and pregnancy, but the effect of these conditions on the levels of the related chemokines eotaxin-2 and eotaxin-3 remains unknown ...
Cristina Mancebo-Pérez, Marta Vidal, Ruth Aguilar, Diana Barrios, Azucena Bardají, Maria Ome-Kaius, Clara Menéndez, Stephen J. Rogerson, Carlota Dobaño, Gemma Moncunill, Pilar Requena   +10 more
doaj   +1 more source

The Effect of IL-35 on the Expression of Nasal Epithelial-Derived Proinflammatory Cytokines

Mediators of Inflammation, 2021
Background. Airway epithelium plays an important role during the development of allergic rhinitis (AR), which is characterized by production of thymic stromal lymphopoietin (TSLP), interleukin 33 (IL-33), and interleukin 25 (IL-25).
Mingrong Nie, Qingxiang Zeng, Luo Xi, Yiquan Tang, Renzhong Luo, Wenlong Liu   +5 more
doaj   +1 more source