High-throughput multi-analyte Luminex profiling implicates eotaxin-1 in ulcerative colitis. [PDF]
PLoS ONE, 2013 Accurate and high-throughput technologies are needed for identification of new therapeutic targets and for optimizing therapy in inflammatory bowel disease.
Lori A Coburn +15 more
doaj +5 more sources
MCP‐1 and eotaxin‐1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes [PDF]
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2016 Introduction MCP‐1 and eotaxin‐1 are encoded on chromosome 17 and have been shown to reduce hippocampal neurogenesis in mice. We investigated whether these chemokines selectively associate with memory in individuals with mild cognitive impairment (MCI ...
Brianne M. Bettcher +12 more
doaj +4 more sources
Orally administered anti-eotaxin-1 monoclonal antibody is biologically active in the gut and alleviates immune-mediated hepatitis: A novel anti-inflammatory personalized therapeutic approach [PDF]
International Journal of Immunopathology and Pharmacology, 2021 Personalized therapies are designed to optimize the safety-to-efficacy ratio by selecting patients with higher response rates based on specific biomarkers.
Tawfik Khoury +3 more
doaj +2 more sources
Diagnostic significance of serum eotaxin-1 level in gastric cancer patients. [PDF]
Dis Markers, 2013 Introduction. Gastric cancer is the second cause of cancer-related deaths worldwide. Delayed diagnosis leads to high mortality rates. Eotaxin-1 was originally discovered as an eosinophil-selective chemoattractant and may play a role in a number of chronic inflammatory diseases, cancer, and other gastrointestinal disorders.
Koç Ü +6 more
europepmc +5 more sources
Analysis of single nucleotide polymorphism in the promoter and protein expression of the chemokine Eotaxin-1 in colorectal cancer patients [PDF]
World Journal of Surgical Oncology, 2007 Background Previous studies suggest that chemokines (chemotactic cytokines) promote and regulate neoplastic progression including metastasis and angiogenesis. The chemokine eotaxin-1 is a powerful eosinophil attractant but also exerts chemotaxis of other
Dienus Olaf +4 more
doaj +2 more sources
Altered eotaxin-1 and interleukin-34 levels in obsessive-compulsive disorder: a case-control observational study in Bangladesh [PDF]
Osong Public Health and Research PerspectivesObjectives Obsessive-compulsive disorder (OCD) is a prevalent mental health condition that impacts daily life. It is thought to be associated with genetic, biological, and structural brain changes, serotonergic abnormalities, altered neuromodulation, and
Syed Ishtiaque Hossain +5 more
doaj +2 more sources
Egyptian Journal of Chest Disease and Tuberculosis, 2014 The aim of this work was to assess eotaxin 1 level in exhaled breath condensate of exacerbated and stable COPD patients in relation to normal subjects.
Gehan Elassal, Rasha Mamdouh
doaj +2 more sources
Eotaxin-1 (CCL11) up-regulation in tears during seasonal allergic conjunctivitis [PDF]
Graefe's Archive for Clinical and Experimental Ophthalmology, 2004 To compare in-season eotaxin-1 levels in tears of patients suffering from seasonal allergic conjunctivitis (SAC) with (1) tears of normal subjects and (2) tears of SAC patients out of season.Tears of 11 SAC patients and six control volunteers were collected during the pollen season.
Eperon, S. +5 more
openaire +4 more sources
Serum C-C motif ligand 11/Eotaxin-1 may serve as a candidate biomarker for postmenopausal osteoporosis [PDF]
Journal of Medical Biochemistry, 2019 Background: The chemokine C-C motif ligand 11, also known as eotaxin-1, has been identified as a novel mediator of inflammatory bone resorption. However, little is known regarding a potential role for CCL11/Eotaxin-1 in postmenopausal osteoporosis ...
Wang Wen +6 more
doaj +2 more sources
Tear and mucus eotaxin-1 and eotaxin-2 in allergic keratoconjunctivitis
Ophthalmology, 2003 Eotaxin-1 and eotaxin-2 are potent eosinophil chemotactic and activating peptides that may be implicated in the pathogenesis of the chronic allergic eye diseases vernal keratoconjunctivitis (VKC) and atopic keratoconjunctivitis (AKC). The purpose of this study was to measure these chemokines in tear and mucus samples of active-disease patients and in ...
Andrea, Leonardi +3 more
core +5 more sources