Results 11 to 20 of about 19,435 (196)
Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders [PDF]
Frontiers in Psychiatry, 2018 Eotaxin-1/CCL11 is a chemokine originally implicated in the selective recruitment of eosinophils into inflammatory sites during allergic reactions, being thoroughly investigated in asthma, allergic rhinitis, and other eosinophil-related conditions ...
Antonio Lucio Teixeira +2 more
exaly +10 more sources
Synephrine Inhibits Eotaxin-1 Expression via the STAT6 Signaling Pathway [PDF]
Molecules, 2014 Citrus contain various flavonoids and alkaloids that have multiple biological activities. It is known that the immature Citrus contains larger amounts of bioactive components, than do the mature plants. Although Citrus flavonoids are well known for their
Kyung-Baeg Roh +6 more
doaj +6 more sources
Betel chewing and arecoline affects eotaxin-1, asthma and lung function. [PDF]
PLoS ONE, 2014 BackgroundBetel nut is commonly used in many countries. Despite evidence suggesting an association with asthma, few studies have investigated the connection between betel nut use and asthma; thus, the underlying mechanism for the association with asthma ...
Tsu-Nai Wang +13 more
doaj +7 more sources
Trans-activation of eotaxin-1 by Brg1 contributes to liver regeneration [PDF]
Cell Death and Disease, 2022 Infiltration of eosinophils is associated with and contributes to liver regeneration. Chemotaxis of eosinophils is orchestrated by the eotaxin family of chemoattractants. We report here that expression of eotaxin-1 (referred to as eotaxin hereafter), but
Zhiwen Fan +14 more
doaj +4 more sources
The “Aging Factor” Eotaxin-1 (CCL11) Is Detectable in Transfusion Blood Products and Increases with the Donor’s Age [PDF]
Frontiers in Aging Neuroscience, 2017 Background: High blood levels of the chemokine eotaxin-1 (CCL11) have recently been associated with aging and dementia, as well as impaired memory and learning in humans. Importantly, eotaxin-1 was shown to pass the blood-brain-barrier (BBB) and has been
Julia Hoefer +5 more
doaj +3 more sources
Distinct Roles Between Eotaxin 1 and Eotaxin 2 in Asthmatic Airways [PDF]
Clinical and Translational AllergyBackground Eotaxins (EOTs), primarily expressed in airway epithelial cells (AECs), act as chemoattractants for eosinophils in asthma pathogenesis. Recent studies have suggested that EOTs have additional functions beyond chemotaxis.
Soyoon Sim +5 more
doaj +4 more sources
Regulation of MMP-3 expression and secretion by the chemokine eotaxin-1 in human chondrocytes [PDF]
Journal of Biomedical Science, 2011 Background Osteoarthritis (OA) is characterized by the degradation of articular cartilage, marked by the breakdown of matrix proteins. Studies demonstrated the involvement of chemokines in this process, and some may potentially serve as diagnostic ...
Chao Pin-Zhir +4 more
doaj +5 more sources
Frontiers in Immunology, 2015 The eosinophil was first named by the brilliant German scientist Paul Ehrlich in 1879, while he was experimenting with aniline dyes to stain blood cells and tissues. He also discovered neutrophils, basophils, and mast cells. The highly basic proteins in cytosolic granules of a small subpopulation of cells in human blood stained vivid pink with the acid
TIMOTHY JOHN WILLIAMS
doaj +6 more sources
Eotaxin-1/CCL11 promotes cellular senescence in human-derived fibroblasts through pro-oxidant and pro-inflammatory pathways [PDF]
Frontiers in Immunology, 2023 IntroductionEotaxin-1/CCL11 is a pivotal chemokine crucial for eosinophil homing to the lungs of asthmatic patients. Recent studies also suggest that CCL11 is involved in the aging process, as it is upregulated in elderly, and correlated with shorter ...
Patrícia Lavandoski +6 more
doaj +4 more sources
Eotaxin-1 in exhaled breath condensate of stable and unstable asthma patients. [PDF]
Respiratory Research, 2010 Background Airway eosinophilia is considered a central event in the pathogenesis of asthma. Eotaxin plays a key role in selective eosinophil accumulation in the airways and, subsequently, their activation and degranulation.
Zietkowski Ziemowit +4 more
doaj +5 more sources