Results 61 to 70 of about 29,712,289 (205)

CCL11 Differentially Affects Post-Stroke Brain Injury and Neuroregeneration in Mice Depending on Age

Cells, 2019
CCL11 has recently been shown to differentially affect cell survival under various pathological conditions including stroke. Indeed, CCL11 promotes neuroregeneration in neonatal stroke mice.
Simone Lieschke, Bozena Zechmeister, Matteo Haupt, Xuan Zheng, Fengyan Jin, Katharina Hein, Martin S. Weber, Dirk M. Hermann, Mathias Bähr, Ertugrul Kilic, Thorsten R. Doeppner   +10 more
doaj   +1 more source

ANDV induces eotaxin-1 in lung tissue models.

, 2016
Levels of Eotaxin-1 in supernatants (pg/ml) from infected models. Eotaxin-1 was not detected in supernatants from uninfected models at any time-point (data not shown). Data represent mean ± SEM of two independent experiments.
Clas Ahlm (337169), Karin B. Sundström (337165), Shawon Gupta (395812), Jonas Klingström (45509), Anh Thu Nguyen Hoang (2265463), Mattias Svensson (251968)   +5 more
core   +1 more source

Immune Clues to Sinus Blues: Linking Biomarkers to Radiologic Score of Rhinosinusitis

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) is a prolonged inflammatory condition of the nasal and paranasal sinuses that significantly affects quality of life. This study examines the relationship between CRS severity (based on Lund‐Mackay [LM] scores), osteitis, and systemic inflammatory markers, including neutrophil‐to‐lymphocyte ratio (NLR ...
Lubna Khreesha, Amer Sawalha, Mohammad Darweesh, Qusai Elfadel, Mohammad Alzoubi, Saif Alhawadi, Faris Alsawair, Fares Habboub, Bashar Alsmady, Mohammad Aljarboa, Hashim Alhammouri   +10 more
wiley   +1 more source

Eotaxin-2/CCL24 and eotaxin-3/CCL26 exert differential profibrogenic effects on human lung fibroblasts

, 2010
BACKGROUND: Eotaxin-2/CCL24 and eotaxin-3/CCL26 play an important role in eosinophil chemotaxis and activation in asthma. We previously demonstrated that eotaxin/CCL11 is profibrogenic for human lung fibroblasts.
Reich R, Levi Schaffer F, PUXEDDU, ILARIA, Kohan M, Berkman N.   +4 more
core   +1 more source

Dipeptidyl Peptidase‐4 Inhibitor Use and Risk of Pemphigus Vulgaris and Foliaceus: A Retrospective Cohort Study Using Databases of the Korea National Health Insurance Claims and the National Health Screening Examination

The Journal of Dermatology, EarlyView.
ABSTRACT Although population‐based studies have reported an increased risk of bullous pemphigoid and pemphigus associated with dipeptidyl peptidase‐4 (DPP‐4) inhibitors, there is limited, well‐designed epidemiological evidence for pemphigus vulgaris (PV), which has only been supported by case reports thus far.
Jaein Lee, Jae Hyun Bae, Seokyung Hahn
wiley   +1 more source

Elevated CO2 and Temperature Alter Grass Pollen's Ability to Modify Transcriptome and Function of the Nasal Epithelium

Allergy, EarlyView.
We exposed human nasal epithelial tissues to pollen from grasses grown under different climate treatments (temperature and CO2). Pollen weakened epithelial tight junctions and altered cytokine‐related gene expression, with similar protein‐level effects.
Tarleena Tossavainen, Tanja Turunen, Maria‐Viola Martikainen, Miisa Kankaanpää, Marjo Malinen, Marjut Roponen   +5 more
wiley   +1 more source

Effect of cigarette smoke on counts of immunoreactive cells to eotaxin-1 and eosinophils on the nasal mucosa in young patients with perennial allergic rhinitis

Brazilian Journal of Otorhinolaryngology
Introduction: In teenagers with perennial allergic rhinitis, exposure to tobacco cigarette smoke increases the count of eosinophils in the nasal mucosa; the recruitment of eosinophils arises from the combined action of a number of cellular and molecular ...
Bertha Beatriz Montaño-Velázquez, Eulalia Beatriz Flores-Rojas, Francisco Javier García-Vázquez, Silvio Jurado-Hernandez, Marco Antonio Venancio Hernández, Angélica Kathya Alanis Flores, Kathrine Jáuregui-Renaud   +6 more
doaj   +1 more source

Molecular Characterization of Non‐Specific Esophagitis Reveals a Distinct Non‐Eosinophilic Phenotype With Fibrotic Traits

Allergy, EarlyView.
This study comprehensively characterizes non‐specific esophagitis and elucidates eosinophil‐independent fibrosis mechanisms. NSE appears to be a distinct fibrotic phenotype of the esophagus, without any considerable overlap with GERD and other chronic inflammatory disorders such as EoE or lymphocytic esophagitis.
Marc Pfefferle, Darko Stojkov, Dagmar Simon, Emilie Gueguen, Marcin Wawrzyniak, Margaret H. Collins, Mirna Chehade, Evan S. Dellon, Glenn T. Furuta, Ikuo Hirano, Nirmala Gonsalves, Fouad J. Moawad, Luc Biedermann, Alain M. Schoepfer, Alex Straumann, Hans‐Uwe Simon, Thomas Greuter   +16 more
wiley   +1 more source

Expression of RANTES, eotaxin-2, ICAM-1, LFA-1 and CCR-3 in chronic rhinosinusitis patients with nasal polyposis Expressão de RANTES, eotaxina-2, ICAM-1, LFA-1 e CCR-3 em pacientes com rinossinusite crônica associada à polipose nasossinusal

Acta Cirúrgica Brasileira, 2012
PURPOSE: To compare gene expression of the chemokines RANTES and eotaxin-2, its receptor, CCR-3, adhesion molecule ICAM-1 and its receptor LFA-1 in eosinophilic polyps and in control normal nasal mucosa.
Fransérgio Emílio Cavallari, Fabiana Cardoso Pereira Valera, Aline Jorge Gallego, Rafael Rossell Malinsky, Daniel Salgado Küpper, Cristiane Milanezi, João Santana da Silva, Edwin Tamashiro, Wilma Terezinha Anselmo-Lima   +8 more
doaj   +1 more source

Renal expression of cytokines and chemokines in diabetic nephropathy

BMC Nephrology, 2020
Background Diabetic nephropathy (DN) is the leading cause of end-stage renal disease worldwide. Inflammatory mediators have been implicated in the pathogenesis of DN, thus considered an inflammatory disease.
Liliane Silvano Araújo, Bianca Gonçalves Silva Torquato, Crislaine Aparecida da Silva, Maria Luíza Gonçalves dos Reis Monteiro, Ana Luisa Monteiro dos Santos Martins, Marcos Vinícius da Silva, Marlene Antônia dos Reis, Juliana Reis Machado   +7 more
doaj   +1 more source