Results 111 to 120 of about 11,193 (295)

PGE2 binding to EP2 promotes ureteral stone expulsion by relaxing ureter via the cAMP-PKA pathway

BMC Urology
Background This study investigated the relaxation effect of PGE2 on the ureter and its role in promoting calculi expulsion following calculi development.
Hao Su, Wenyan Zhou, Weiming Chen, Ke Yang, Meng Yang, Hu He, Cheng Qian, Dongbo Yuan, Kehua Jiang, Jianguo Zhu   +9 more
doaj   +1 more source

Effectiveness of written exposure therapy for reducing depressive symptoms in individuals with posttraumatic stress disorder: A systematic review

Journal of Traumatic Stress, EarlyView.
Abstract Written exposure therapy (WET) has become increasingly recognized alongside other evidence‐based treatments of posttraumatic stress disorder (PTSD), with a rapidly growing evidence base. However, current research has not yet investigated the effect of WET on comorbid depression.
Eunice Tao, Bruce Arroll, Andrew Jull, Fiona Moir, Rachel Roskvist, Nicholas Hoeh, Ranche Johnson, Nika Nova   +7 more
wiley   +1 more source

Earlier strength recovery with partial‐thickness versus full‐thickness quadriceps tendon graft for anterior cruciate ligament reconstruction in competitive soccer players

Knee Surgery, Sports Traumatology, Arthroscopy, EarlyView.
Abstract Purpose This study aimed to compare strength recovery, functional and clinical outcomes between full‐ and partial‐thickness quadriceps tendon autografts for 12 months post‐operatively and to examine the clinical implications of graft thickness in anterior cruciate ligament reconstruction among non‐professional competitive soccer players ...
Jose Luis Martin‐Alguacil, Manuel Arroyo‐Morales, Maria Lopez‐Garzon, Víctor Bolívar‐Arroyo, Irene Cantarero‐Villanueva, Juan M. Fernández‐Domínguez, Jose M. Rodriguez‐Delgado   +6 more
wiley   +1 more source

Synergistic Regulation of Soil Function and Wind Erosion Resistance by Sand Barriers, Vegetation, and Artificial Biological Crust in the Tengger Desert

Land Degradation &Development, EarlyView.
ABSTRACT Aeolian desertification poses a critical threat to ecosystem stability in arid regions worldwide. Although the combination of sand barriers and vegetation has been widely applied for sand fixation, its long‐term effectiveness is constrained by barrier degradation, slow natural development of biological soil crusts (BSCs), and the resulting ...
Bin Pan, Chen Meng
wiley   +1 more source

The Physical, Emotional, and Autonomous Anthropomorphism of Service Chatbots

Psychology &Marketing, EarlyView.
ABSTRACT Prior research on chatbot anthropomorphism has often treated it as a unidimensional construct, producing inconsistent findings regarding how human‐like design cues shape user responses. This study conceptualizes anthropomorphism as a multidimensional higher‐order perception comprising three distinct forms of anthropomorphic attribution ...
Yangjuan Hu, Fulya Acikgoz, Shubin Yu
wiley   +1 more source

Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties

, 2018
The prostaglandin E2 receptor, EP2, plays an important role in physiology and in a variety of pathological conditions. Studies indicate that EP2 is pro-inflammatory in chronic peripheral and central nervous system disease and cancer models.
Ray Dingledine (1319991), Avijit Banik, Wenyi Wang, Radhika Amaradhi (5979716), Ray Dingledine, Thota Ganesh (1319988), Wenyi Wang (169392), Thota Ganesh, Radhika Amaradhi, Avijit Banik (5919077)   +9 more
core   +1 more source

How Personal Pronouns Shape Persuasion

Psychology &Marketing, EarlyView.
ABSTRACT Communication often involves personal pronouns. Consumers, for example, frequently say “I love this restaurant” or “you'll enjoy those shoes.” How do first‐person (e.g., I) and second‐person (e.g., you) singular pronouns shape persuasion? Are communicators correct about which ones are more effective?
Wenyan Yin, Jonah Berger, Yanliu Huang
wiley   +1 more source

When AI Remembers: Investigating the Dual Role of Long‐Term Memory in Chatbots

Psychology &Marketing, EarlyView.
ABSTRACT This research investigates the dual role of long‐term memory (LTM) in AI chatbots and its impact on customer outcomes. Drawing on Mind Perception Theory and Privacy Calculus Theory, we conceptualize LTM as a continuity‐based design capability that may be interpreted as a functional service feature, a privacy‐relevant cue, or a basis for ...
Maedeh Parvizian, Lucas Whittaker, Hassan Kalantari Daronkola, Jessica Pallant, Lester Johnson   +4 more
wiley   +1 more source

Allopregnanolone relieves paclitaxel induced mechanical hypersensitivity via inhibiting spinal cord PGE2-EP2 mediated microglia-neuron signaling

IBRO Neuroscience Reports
Chemotherapy-induced neuropathic pain (CINP) is a serious adverse effect of commonly used chemotherapeutics. Neurosteroid allopregnanolone is suggested to modulate the expression of various receptors or enzymes that involved in pain perception ...
Kunlin Guo, Lei Gao, Ping Li, Shanwu Feng, Liping Zhao, Xian Wang   +5 more
doaj   +1 more source

Evaluating the efficacy of obturator cryoneurolysis for hip adductor spasticity: An observational, prospective study

PM&R, EarlyView.
Abstract Background Hip adductor spasticity is a common affliction among patients with disorders of the central nervous system. Cryoneurolysis is a novel intervention for spasticity involving the application of extreme cold to a nerve. This induces axonal breakdown, relieving spasticity.
Fraser MacRae, Mahdis Hashemi, Paul Winston   +2 more
wiley   +1 more source