Results 31 to 40 of about 608 (136)

Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence and virulence from attenuated BeninΔDP148R [PDF]

open access: yes, 2021
AbstractThe limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress towards vaccine development. In this study we investigated the effect of deleting combinations of different genes from a previously attenuated virus, BeninΔDP148R on: virus replication in macrophages, virus ...
Vlad Petrovan   +7 more
openaire   +1 more source

Growth Kinetics and Protective Efficacy of Attenuated ASFV Strain Congo with Deletion of the EP402 Gene

open access: yesViruses, 2021
African swine fever (ASF) is an emerging disease threat to the swine industry worldwide. There is no vaccine against ASF, and progress is hindered by a lack of knowledge concerning the extent of ASFV strain diversity and the viral antigens conferring ...
Galina Koltsova   +5 more
doaj   +1 more source

CD2v interacts with Adaptor Protein AP-1 during African swine fever infection [PDF]

open access: yes, 2015
African swine fever virus (ASFV) CD2v protein is believed to be involved in virulence enhancement, viral hemadsorption, and pathogenesis, although the molecular mechanisms of the function of this viral protein are still not fully understood.
Pérez-Núñez, Daniel   +6 more
core   +11 more sources

Molecular Characterization of African Swine Fever Virus From 2019-2020 Outbreaks in Guangxi Province, Southern China

open access: yesFrontiers in Veterinary Science, 2022
African swine fever virus (ASFV) causes contagious hemorrhagic disease of pigs with high morbidity and mortality. To identify the molecular characteristics of ASFV strains circulating in Guangxi province, southern China, a total of 336 tissue samples ...
Kaichuang Shi   +6 more
doaj   +1 more source

Diversity and emergence of new variants of African swine fever virus Genotype I circulating in domestic pigs in Nigeria (2016–2018)

open access: yesVeterinary Medicine and Science, Volume 9, Issue 2, Page 819-828, March 2023., 2023
Three partial genes sequences p72 capsid protein of the B646L, p54 envelope protein of E183L, and the central variable region (CVR) within B602L of African swine fever virus from Nigeria were characterised. We found an increase in tandem repeat sequence (TRS) variants, and three variants (Tet‐21b, Tet‐31 and Tet‐34) were identified for the first time ...
C. Masembe   +5 more
wiley   +1 more source

Investigation of the First African Swine Fever Outbreak in a Domestic Pig Farm in Hong Kong

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
In this study, we describe the epidemiological investigation of the first African swine fever (ASF) outbreak in a local domestic pig farm in the New Territories of Hong Kong in 2021. In the outbreak farm, several affected pigs presented clinical and pathological signs consistent with ASF, while the remaining pigs showed nonspecific clinical signs or ...
Yun Young Go   +19 more
wiley   +1 more source

Dynamics of Serological and Mucosal Antibody Responses against African Swine Fever Viruses in Experimentally Infected Pigs

open access: yesTransboundary and Emerging Diseases, Volume 2023, Issue 1, 2023., 2023
African swine fever virus (ASFV) is a lethal swine pathogen, and there is no effective vaccine or treatment available for ASFV infection. Recently, the occurrence of ASFV genotype I and genotype II natural mutants that manifest as subacute, longer‐incubation, or persistent infections poses threats to preventing ASFV infection.
Qingyun Xie   +10 more
wiley   +1 more source

Vaccines for African swine fever: an update [PDF]

open access: yes, 2023
African swine fever (ASF) is a fatal infectious disease of swine caused by the African swine fever virus (ASFV). Currently, the disease is listed as a legally notifiable disease that must be reported to the World Organization for Animal Health (WOAH ...
Haojie Zhang   +6 more
core   +1 more source

Novel method for sub‐grouping of genotype II African swine fever viruses based on the intergenic region between the A179L and A137R genes

open access: yesVeterinary Medicine and Science, Volume 8, Issue 2, Page 607-609, March 2022., 2022
We report the development of a novel method for sub‐grouping genotype II African swine fever virus based on the intergenic region between the A179L and A137R genes. We have identified an insertion or deletion of an 11‐nucleotide sequence that may help analysis of the evolution and relationships between geographically separated outbreaks.
Ha Thi Thanh Tran   +8 more
wiley   +1 more source

Recombinant African Swine Fever Virus Arm/07/CBM/c2 Lacking CD2v and A238L Is Attenuated and Protects Pigs against Virulent Korean Paju Strain

open access: yesVaccines, 2022
African swine fever (ASF) is an obligated declaration swine disease, provoking farm isolation measures and the closing of affected country boarders. ASF virus (ASFV) is currently the cause of a pandemic across China and Eurasia.
Daniel Pérez-Núñez   +11 more
doaj   +1 more source

Home - About - Disclaimer - Privacy