Deletion of the CD2 Gene in the Virulent ASFV Congo Strain Affects Viremia in Domestic Swine, but Not the Virulence [PDF]
Animals, 2023 African swine fever (ASF) is an infectious disease that causes the most significant losses to the pig industry. One of the effective methods for combating this disease could be the development of vaccines.
Andrey Koltsov +2 more
exaly +4 more sources
Journal of Virology, 2021 African swine fever virus (ASFV) causes a disease of domestic pigs and wild boar which results in death of almost all infected animals. The disease has a high economic impact, and no vaccine is available.
Vlad Petrovan +7 more
+6 more sources
Protection Evaluation of a Five-Gene-Deleted African Swine Fever Virus Vaccine Candidate Against Homologous Challenge [PDF]
Frontiers in Microbiology, 2022 African swine fever virus (ASFV) represents a serious threat to the global swine industry, and there are no safe or commercially available vaccines. Previous studies have demonstrated that inactivated vaccines do not provide sufficient protection against
Zhenhua Xie +25 more
doaj +3 more sources
Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence and virulence from attenuated BeninΔDP148R [PDF]
, 2021 AbstractThe limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress towards vaccine development. In this study we investigated the effect of deleting combinations of different genes from a previously attenuated virus, BeninΔDP148R on: virus replication in macrophages, virus ...
Vlad Petrovan +7 more
openalex +2 more sources
Molecular Characterization of African Swine Fever Viruses Circulating in Can Tho City, Vietnam
Veterinary Medicine International, 2023 African swine fever (ASF) is a highly contagious and deadly viral disease in domestic and feral pigs. Since 2018, the disease has spread and caused large socioeconomic consequences to the pig industry in several Asian countries including China, Vietnam ...
Nguyen Duc Hien +4 more
doaj +2 more sources
Phylogenomic Comparison of Seven African Swine Fever Genotype II Outbreak Viruses (1998–2019) Reveals the Likely African Origin of Georgia 2007/1 [PDF]
Pathogens, 2023 Since the initial report of African swine fever (ASF) in Kenya in 1921, the disease has predominantly been confined to Africa. However, in 2007, an ASF genotype II virus of unknown provenance was introduced to Georgia.
Rivalani F. Mthombeni +4 more
doaj +3 more sources
Seroimmunotyping of African swine fever virus [PDF]
Frontiers in Microbiology, 2023 The extreme genetic and immunobiological heterogeneity exhibited by the African swine fever virus (ASFV) has been a significant impediment in the development of an efficacious vaccine against this disease.
Alexey D. Sereda +6 more
doaj +3 more sources
Viruses, 2021 African swine fever (ASF) is an emerging disease threat to the swine industry worldwide. There is no vaccine against ASF, and progress is hindered by a lack of knowledge concerning the extent of ASFV strain diversity and the viral antigens conferring ...
Galina Burmakina +2 more
exaly +3 more sources
A quadruple fluorescence quantitative PCR method for the identification of wild strains of african swine fever and gene-deficient strains [PDF]
Virology Journal, 2023 Background Originating in Africa, African swine fever (ASF) was introduced to China in 2018. This acute and highly virulent infectious disease affects domestic pigs. The World Organization for Animal Health has listed it as a statutory reportable disease,
Xuezhi Zuo +10 more
doaj +2 more sources
An Update on African Swine Fever Virology [PDF]
Viruses, 2019 Animal diseases constitute a continuing threat to animal health, food safety, national economy, and the environment. Among those, African swine fever (ASF) is one of the most devastating viruses affecting pigs and wild suids due to the lack of vaccine or
Axel Karger +8 more
doaj +3 more sources