Results 1 to 10 of about 660 (141)

Deletion of the EP402R Gene from the Genome of African Swine Fever Vaccine Strain ASFV-G-∆I177L Provides the Potential Capability of Differentiating between Infected and Vaccinated Animals [PDF]

Viruses
The African swine fever virus (ASFV) mutant ASFV-G-∆I177L is a safe and efficacious vaccine which induces protection against the challenge of its parental virus, the Georgia 2010 isolate.
Elizabeth Ramirez-Medina, Lauro Velazquez-Salinas, Ediane Silva   +2 more
exaly   +8 more sources

Double Deletion of EP402R and EP153R in the Attenuated Lv17/WB/Rie1 African Swine Fever Virus (ASFV) Enhances Safety, Provides DIVA Compatibility, and Confers Complete Protection Against a Genotype II Virulent Strain [PDF]

Vaccines
Background/Objectives: African swine fever virus (ASFV) is a devastating disease affecting domestic and wild suids and causing significant economic losses in the global pig industry.
Carmina Gallardo, Jovita Fernandez-Pinero, Erwin van den Born   +2 more
exaly   +9 more sources

Rapid Identification for Serotyping of African Swine Fever Virus Based on the Short Fragment of the EP402R Gene Encoding for CD2-Like Protein [PDF]

Acta Veterinaria, 2021
The first confirmed case of African swine fever (ASF) in Vietnam was officially reported in February 2019. To date, the ASF virus (ASFV) has been detected in all 63 cities/provinces in Vietnam. In order to get a better understanding of the potential role
Thanh Tran Ha Thi, Duc Truong Anh, Viet Ly Duc, Van Hoang Tuan, Thi Nguyen Chinh, Thi Chu Nhu, Thi Nguyen Huyen, Vu Dang Hoang   +7 more
doaj   +6 more sources

Co-Deletion of A238L and EP402R Genes from a Genotype IX African Swine Fever Virus Results in Partial Attenuation and Protection in Swine [PDF]

Viruses, 2022
African swine fever virus (ASFV) is the causative agent of African swine fever (ASF), resulting in up to 100% mortality in pigs. Although endemic in most sub-Saharan African countries, where all known ASFV genotypes have been reported, the disease has ...
Hussein M Abkallo, Johanneke D Hemmink, Emmanuel Mulaya Khazalwa   +2 more
exaly   +7 more sources

The Development of a Multiplex Real-Time Quantitative PCR Assay for the Differential Detection of the Wild-Type Strain and the MGF505-2R, EP402R and I177L Gene-Deleted Strain of the African Swine Fever Virus [PDF]

Animals, 2022
African swine fever virus (ASFV) causes African swine fever (ASF), a devastating hemorrhagic disease of domestic pigs and wild boars. Currently, the MGF505R, EP402R (CD2v) and I177L gene-deleted ASFV strains were confirmed to be the ideal vaccine ...
Kang Zhao, Kaichuang Shi, Feng Long
exaly   +6 more sources

The deletion of the EP402R and MGF505/360 genes attenuates a genotype I/II recombinant ASFV but fails to confer complete protection against homologous or genotype II challenge in pigs [PDF]

Emerging Microbes and Infections
African swine fever (ASF), a pig disease caused by ASFV, is highly contagious and often lethal. The recent emergence of novel ASFV with I/II genomic recombination has posed significant challenges to global ASF prevention and control.
Lang Gong, Hong-jun Chen
exaly   +8 more sources

Attempts at the development of a recombinant African swine fever virus strain with abrogated EP402R, 9GL , and A238L gene structure using the CRISPR/Cas9 system [PDF]

Journal of Veterinary Research (Poland), 2020
African swine fever (ASF) is a pressing economic problem in a number of Eastern European countries. It has also depleted the Chinese sow population by 50%.
Grzegorz Woźniakowski, Natalia Mazur-Panasiuk, Marek Walczak   +2 more
exaly   +5 more sources

Development and Application of a Duplex Droplet Digital Polymerase Chain Reaction Assay for Detection and Differentiation of EP402R-Deleted and Wild-Type African Swine Fever Virus

Frontiers in Veterinary Science, 2022
African swine fever (ASF) is a highly fatal porcine disease caused by the African swine fever virus (ASFV), and resulting in huge economic losses across the globe. ASF has been raging in China for 3 years, and recently EP402R-deleted ASFV strains emerged,
Junhai Zhu, Junhai Zhu, Junhai Zhu, Junhai Zhu, Junhai Zhu, Weijun Jian, Weijun Jian, Weijun Jian, Weijun Jian, Yifan Huang, Yifan Huang, Yifan Huang, Yifan Huang, Qi Gao, Qi Gao, Qi Gao, Qi Gao, Fei Gao, Fei Gao, Fei Gao, Fei Gao, Huahan Chen, Huahan Chen, Huahan Chen, Huahan Chen, Guihong Zhang, Guihong Zhang, Guihong Zhang, Guihong Zhang, Ming Liao, Ming Liao, Ming Liao, Ming Liao, Ming Liao, Wenbao Qi, Wenbao Qi, Wenbao Qi, Wenbao Qi, Wenbao Qi   +38 more
exaly   +6 more sources

REPLICATION OF RECOMBINANT AFRICAN SWINE FEVER VIRUSES WITH EP402R GENE DELETION IN VIVO

Биотехнология в растениеводстве, животноводстве и сельскохозяйственной микробиологии, 2021
Африканская чума свиней - контагиозная вирусная геморрагическая болезнь домашних и диких свиней с летальностью до 100 %, сопровождающаяся лихорадкой, цианозом кожи, диареей, судорогами (Montgomery, 1921). Вирус АЧС - крупный икосаэдрический цитоплазматический вирус семейства Asfarviridae (Dixon et al., 2012).
А.Ю. Кольцов, Sergey Krutko, С.В. Белов, Н.С. Холод, Alexey S. Korotin, М.М. Сухер, Г.С. Кольцова   +6 more
exaly   +3 more sources

ANALYSIS OF THE DOMESTIC ISOLATES OF THE AFRICAN SWINE FEVER VIRUS BY THE EP402R GENETIC MARKER

Agrobiotechnologies and digital farming, 2022
Recently, the problem of convergent evolution of pathogens (viruses, bacteria) and macroorganism has been of great interest. In turn, the study of evolutionary variability, from the point of view of the virocentric model of evolution, can become an additional link in determining the direction of the evolution of life as a whole.
Adylya Kamilevna Sibgatullova, Nasiya Daminova, S.V. Tyulkin   +2 more
exaly   +4 more sources