Specific Detection of African Swine Fever Virus Variants: Novel Quadplex Real-Time PCR Assay with Internal Control [PDF]
African swine fever (ASF), a highly contagious and lethal viral disease, continues to devastate the global swine industry. The emergence of ASF virus (ASFV) variants with varying genomic deletions poses significant challenges for ASF control.
Lihua Wang +12 more
doaj +2 more sources
Saccharomyces cerevisiae oral immunization in mice using multi-antigen of the African swine fever virus elicits a robust immune response [PDF]
African swine fever virus (ASFV) is one of the most complex viruses. ASFV is a serious threat to the global swine industry because no commercial vaccines against this virus are currently available except in Vietnam. Moreover, ASFV is highly stable in the
Shuo Gao +17 more
doaj +2 more sources
Designing a multi-epitope vaccine against African swine fever virus using immunoinformatics approach [PDF]
African swine fever (ASF) is a highly contagious and fatal haemorrhagic disease affecting domestic and wild pigs, with no effective vaccine currently available.
Dhithya Venkateswaran +6 more
doaj +2 more sources
Development of Real-Time and Lateral Flow Dipstick Recombinase Polymerase Amplification Assays for the Rapid Field Diagnosis of MGF-505R Gene-Deleted Mutants of African Swine Fever Virus [PDF]
Pigs are susceptible to the deadly infectious disease known as African swine fever (ASF), which is brought on by the African swine fever virus (ASFV). As such, prompt and precise disease detection is essential. Deletion of the virulence-related genes MGF-
Jizhou Lv +8 more
doaj +2 more sources
Recombinant vaccinia vectored ASFV vaccine enhances swine survival against genotype II challenge [PDF]
The African Swine Fever Virus (ASFV) poses a major threat to global livestock production by infecting both domestic and wild pigs, causing significant economic loss.
Lanlan Dong +12 more
doaj +2 more sources
Resurgence of Type III IGR Between I73R and I329L in Wild Boars With African Swine Fever in South Korea in 2023. [PDF]
The African swine fever virus (ASFV) causes African swine fever (ASF), a highly lethal disease affecting domestic pigs and wild boars. Since its initial outbreak in October 2019 in Yeoncheon, Gyeonggi Province, ASF has continued to spread in South Korea.
Kim G +4 more
europepmc +2 more sources
CD2v interacts with Adaptor Protein AP-1 during African swine fever infection [PDF]
African swine fever virus (ASFV) CD2v protein is believed to be involved in virulence enhancement, viral hemadsorption, and pathogenesis, although the molecular mechanisms of the function of this viral protein are still not fully understood.
Pérez-Núñez, Daniel +6 more
core +11 more sources
Three partial genes sequences p72 capsid protein of the B646L, p54 envelope protein of E183L, and the central variable region (CVR) within B602L of African swine fever virus from Nigeria were characterised. We found an increase in tandem repeat sequence (TRS) variants, and three variants (Tet‐21b, Tet‐31 and Tet‐34) were identified for the first time ...
C. Masembe +5 more
wiley +1 more source
Investigation of the First African Swine Fever Outbreak in a Domestic Pig Farm in Hong Kong
In this study, we describe the epidemiological investigation of the first African swine fever (ASF) outbreak in a local domestic pig farm in the New Territories of Hong Kong in 2021. In the outbreak farm, several affected pigs presented clinical and pathological signs consistent with ASF, while the remaining pigs showed nonspecific clinical signs or ...
Yun Young Go +19 more
wiley +1 more source
Emergence of Microvariants of African Swine Fever Virus Genotype II in the Asia-Pacific. [PDF]
African swine fever virus (ASFV) is a highly stable DNA virus showing little genetic variation among genomes. This genetic stability has often posed challenges in tracking variants and identifying potential transmission chains as ASFV spreads into new regions.
O'Dwyer J +9 more
europepmc +2 more sources

