Results 51 to 60 of about 608 (136)

Deletion of CD2-Like (CD2v) and C-Type Lectin-Like (EP153R) Genes from African Swine Fever Virus Georgia-∆9GL Abrogates Its Effectiveness as an Experimental Vaccine

Viruses, 2020
African swine fever virus (ASFV) is currently the most dreaded infectious disease affecting the global swine production industry. There is no commercial vaccine available, making the culling of infected animals the current solution to control outbreaks ...
Douglas P. Gladue, Vivian O’Donnell, Elizabeth Ramirez-Medina, Ayushi Rai, Sarah Pruitt, Elizabeth A. Vuono, Ediane Silva, Lauro Velazquez-Salinas, Manuel V. Borca   +8 more
doaj   +1 more source

Genetic characterisation of six novel African swine fever viruses isolated from a pig, warthog, wild boar, and ticks [PDF]

, 2021
African swine fever (ASF) is a disease that affects domestic pigs and wild boars, resulting in up to 100% case fatality rate, and there is currently no effective treatment or vaccine.
Ndlovu, Sandy Sibusiso
core   +1 more source

Temporally integrated transcriptome analysis reveals ASFV pathology and host response dynamics [PDF]

, 2022
African swine fever virus (ASFV) causes a lethal swine hemorrhagic disease and is currently responsible for widespread damage to the pig industry. The pathogenesis of ASFV infection and its interaction with host responses remain poorly understood.
Asif Ahsan, Hanying Jia, Lin Lv, Lin Lv, Ning Shen, Ning Shen, Teng Chen, Tianyun Zhang, Xiaoyang Zhao, Yanyan Zhang, Zhiqiang Shen, Zhiqiang Shen   +11 more
core   +1 more source

African Swine Fever Virus CD2v Protein Induces β-Interferon Expression and Apoptosis in Swine Peripheral Blood Mononuclear Cells

Viruses, 2021
African swine fever (ASF) is a hemorrhagic disease of swine characterized by massive lymphocyte depletion in lymphoid tissues due to the apoptosis of B and T cells, a process likely triggered by factors released or secreted by infected macrophages.
Sabal Chaulagain, Gustavo A. Delhon, Sushil Khatiwada, Daniel L. Rock   +3 more
doaj   +1 more source

Full genome sequence analysis of African swine fever virus isolates from Cameroon: [Preprint] [PDF]

, 2023
African swine fever is a devastating disease of domestic pigs that has spread across the globe since its introduction into Georgia in 2007. The etiological agent is a large double-stranded DNA virus with a genome of 170 to 180 kb in length depending on ...
Batten, Carrie, Dixon, Linda K, Forth, Jan Hendrik, Foster, Thomas J, Freimanis, Graham, Goatley, Lynnette C, Netherton, Chris, Quershi, Mehnaz, Tennakoon, Chandana, Wade, Abel   +9 more
core   +1 more source

Identification of a new cell-penetrating peptide derived from the african swine fever virus CD2v protein

Drug Delivery, 2021
The African swine fever virus (ASFV) is a huge and complex DNA virus that can lead to the acute death of pigs and cause huge losses to the global swine industry.
Shunli Yang, Xinming Zhang, Yuying Cao, Shuo Li, Junjun Shao, Shiqi Sun, Huichen Guo, Shuanghui Yin   +7 more
doaj   +1 more source

REVIEW: MENINGKATKAN POPULASI TERNAK BABI MELALUI TEKNOLOGI REPRODUKSI PASCA AFRICAN SWINE FEVER [PDF]

, 2022
The purpose of writing this review is to determine the role of reproductive technology in increasing the population of pigs after the African Swine Fever (ASF) outbreak.
Rinca, Korbinianus Feribertus
core   +1 more source

ASF virus replication features in the presence of recombinant proteins CD2v, pX69R and pE248R

Вопросы вирусологии, 2019
Introduction. African swine fever (ASF), sever hemorrhagic disease of swine caused by a large DNA virus of the Asfaviridae family. Since there are no effective and safe vaccines against ASF yet, it is urgent to study the functions of its proteins, which ...
A. Mazloum, I. U. Zhukov, E. B. Aronova, A. S. Igolkin, N. N. Vlasova   +4 more
doaj   +1 more source

Mucosal and cellular immune responses elicited by nasal and intramuscular inoculation with ASFV candidate immunogens

Frontiers in Immunology, 2023
African swine fever (ASF) is an infectious disease caused by African swine fever virus (ASFV) that is highly contagious and has an extremely high mortality rate (infected by virulent strains) among domestic and wild pigs, causing huge economic losses to ...
Lulu Xu, Lulu Xu, Lulu Xu, Fei Hao, Fei Hao, Fei Hao, Dae Gwin Jeong, Rong Chen, Rong Chen, Yuan Gan, Yuan Gan, Lei Zhang, Lei Zhang, Minjoo Yeom, Jong-Woo Lim, Yanfei Yu, Yanfei Yu, Yun Bai, Yun Bai, Zhiyong Zeng, Yongjie Liu, Qiyan Xiong, Qiyan Xiong, Guoqing Shao, Guoqing Shao, Yuzi Wu, Yuzi Wu, Zhixin Feng, Zhixin Feng, Zhixin Feng, Zhixin Feng, Daesub Song, Xing Xie, Xing Xie, Xing Xie, Xing Xie   +35 more
doaj   +1 more source

A52 MERS coronaviruses from camels in Africa exhibit region-dependent genetic diversity [PDF]

, 2019
Middle East respiratory syndrome coronavirus (MERS-CoV) causes a zoonotic respiratory disease of global public health concern, and dromedary camels are the only proven source of this zoonotic infection.
Chan, Michael C.W., Chevalier, Véronique, Chu, Daniel K.W., Fassi-Fihri, Ouafaa, Hui, Kenrie P.Y., Miguel, Eve, Oladipo, J.O., Peiris, J.S.M., Perera, Ranawaka A.P.M., So, Ray T.Y., Traore, A., Zhou, Ziqi   +11 more
core   +1 more source