Results 11 to 20 of about 7,622 (127)

Molecular Characterization of Virulent Genes and Antimicrobial Resistance Patterns of Escherichia coli Isolated From Calf Scours in Western Iran. [PDF]

Vet Med Sci
This study in Western Iran analysed E. coli in diarrhoeic neonatal calves and identified 307 isolates from 350 faecal samples. The pathotypes included EHEC (36.59%), EPEC (20.42%), ETEC (14.46%), STEC (12.34%) and NTEC (11.48%), with four STEC O157:H7 isolates. Serotypes O103 and O15 were the most common.
Ahmadi E, Firouzabadi MSS, Rad SAM, Ghorbani S.   +3 more
europepmc   +2 more sources

Genomic Epidemiology and Machine Learning-Based Drug Discovery for Antimicrobial Resistant Diarrheagenic Escherichia coli. [PDF]

Microbiologyopen
This study integrates genomic epidemiology and machine learning–based virtual screening to identify novel therapeutic candidates, Alatamide and Isosativan, with strong binding stability against multidrug‐resistant diarrheagenic Escherichia coli virulence targets, highlighting computational drug discovery as a promising strategy to combat antimicrobial ...
Masood A, Noor F, Rehman A, Barq MG, Iqbal S, Ali MQ, Ahmad S, Naqvi SZH.   +7 more
europepmc   +2 more sources

EPEC puts actin on the Map [PDF]

Nature Reviews Microbiology, 2012
exaly   +2 more sources

Virulence properties of atypical EPEC strains [PDF]

Journal of Medical Microbiology, 1999
Virulence properties of 31 atypical enteropathogenic Escherichia coli (EPEC) strains isolated from cases of diarrhoea were examined. All except two strains adhered to HEp-2 cells in a localised adherence-like (LAL) pattern. With the exception of two strains, all were fluorescent actin staining (FAS) positive.
J S, Pelayo, I C A, Scaletsky, M Z, Pedroso, V, Sperandio, J A, Girón, G, Frankel, L R, Trabulsi   +6 more
openaire   +2 more sources

Enteropathogenic Escherichia coli (EPEC) [PDF]

, 2010
Enteropathogenic Escherichia coli (EPEC) comprise two groups of distinct organisms classified as typical EPEC (tEPEC) and atypical EPEC (aEPEC). tEPEC were leading infantile diarrheal agents in developing countries, whereas aEPEC prevailed in developed countries. Nowadays, tEPEC are less frequent while aEPEC are emerging enteropathogens of children and
Tania AT Gomes, Bertha Gonzalez-Pedrajo
openaire   +1 more source

Epithelial maturity influences EPEC-induced desmosomal alterations [PDF]

Gut Microbes, 2018
Desmosomes are junctional protein complexes that confer strong adhesive capacity to adjacent host cells. In a recent study, we showed that enteropathogenic Escherichia coli (EPEC) disrupts desmosomes, weakens cell-cell adhesion and perturbs barrier function of intestinal epithelial (C2BBe) cells.
Jennifer Lising, Roxas, Gayatri, Vedantam, V K, Viswanathan   +2 more
openaire   +2 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Protective Effects of Potential Probiotic Pediococcus acidilactici 100 Against Multi‐Drug‐Resistant Diarrheal Escherichia coli Strains Induced Changes in Caenorhabditis elegans Model System

Food Safety and Health, EarlyView.
This study shows the protective effects of potential probiotic strain of Pediococci strains against diarrheal Escherichia coli strains in Caenorhabditis elegans model system. The E. coli strains resulted in severe morphological and physiological damage to the worm whereas the probiotic interventions were able to reduce these damages.
Gunjan Sadera, Anjali Jaglan, Lappasi Mohanram VenkataKrishna, Krishnaswamy Balamurugan, Gunjan Goel   +4 more
wiley   +1 more source

Quantitative microbial risk assessment with microbial source tracking for enteric pathogens in southwest Wisconsin private wells [PDF]

J Environ Qual
Abstract Private wells supply drinking water for many households, and their contamination by fecal microbes presents a risk of acute gastrointestinal illness (AGI). Risk is thought to vary by contaminating fecal source, but specific associations with fecal source are unknown for most private wells in the United States. This study characterizes AGI risk
Burch T, Stokdyk J, Heffron J, Opelt S, Firnstahl A.   +4 more
europepmc   +2 more sources

Oligonucleotide probe for detection of the enteropathogenic Escherichia coli (EPEC) adherence factor of localized adherent EPEC [PDF]

Journal of Clinical Microbiology, 1990
The enteropathogenic Escherichia coli adherence factor (EAF) probe detects isolates of enteropathogenic E. coli that exhibit localized adherence to HEp-2 cells. A 21-base oligonucleotide probe was constructed on the basis of a sequence from within the 1-kb EAF probe and was shown to have greater sensitivity and specificity than the EAF fragment probe ...
A E, Jerse, W C, Martin, J E, Galen, J B, Kaper   +3 more
openaire   +2 more sources