Results 11 to 20 of about 28,018 (244)
Ependymoma is a tumor of the brain or spinal cord. The two most common and aggressive molecular groups of ependymoma are the supratentorial ZFTA-fusion associated and the posterior fossa ependymoma group A.
Konstantin Okonechnikov +50 more
doaj +2 more sources
BACKGROUND A methylation-based classification of ependymoma has recently found broad application. However, the diagnostic advantage and implications for treatment decisions remain unclear.
M. Träger +30 more
semanticscholar +2 more sources
Tanycytic Ependymoma: A Challenging Histological Diagnosis [PDF]
Tanycytic ependymoma is a rare form of ependymoma that usually arises in the intramedullary spine. It has a unique histology emphasized by the inconspicuous ependymal pattern of cells and close resemblance to schwannoma and astrocytoma.
Khaled M. Krisht, Meic H. Schmidt
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Extramedullary Conus Ependymoma Involving a Lumbar Nerve Root with Filum Terminale Attachment
Purpose In the current report, we describe a case of an extramedullary ependymoma involving a lumbar nerve root near conus medullaris. Spinal ependymomas commonly present as intramedullary tumors in the cervical or thoracic cord or as tumors arising from
Takashi Moriwaki +4 more
doaj +2 more sources
Intraparenchymal clear cell ependymoma
Clear cell ependymoma (CCE) is an uncommon variant of ependymoma having a predilection for the supratentorial region. Histologically, it bears an uncanny resemblance to oligodendroglioma, central neurocytoma, hemangioblastoma and metastasis from clear ...
Prabal Deb +3 more
doaj +2 more sources
European genetic ancestry associated with risk of childhood ependymoma. [PDF]
BACKGROUND Ependymoma is a histologically defined central nervous system tumor most commonly occurring in childhood. Population-level incidence differences by race/ethnicity are observed, with individuals of European ancestry at highest risk. We aimed to
Chenan Zhang +21 more
semanticscholar +2 more sources
The Pediatric Ependymoma Protein Database (PEPD)
Proteomics, through application of modern high-end mass spectrometric (MS) approaches, offers the advantage of in-depth analysis of cancer tissues regarding their protein composition.
George Th. Tsangaris +1 more
doaj +2 more sources
Ependymoma: Evaluation and Management Updates
To review state of art and relevant advances in the molecular genetics and management of ependymomas of children and adults. Ependymomas may occur either in the brain or in the spinal cord.
R. Rudà +3 more
semanticscholar +1 more source
ZFTA-RELA Dictates Oncogenic Transcriptional Programs to Drive Aggressive Supratentorial Ependymoma
Over 60% of supratentorial (ST) ependymomas harbor a ZFTA-RELA (ZRfus) gene fusion (formerly C11orf95-RELA). To study the biology of ZRfus, we developed an autochthonous mouse tumor model using in utero electroporation (IUE) of the embryonic mouse brain.
A. Arabzade +40 more
semanticscholar +1 more source
Pediatric ependymoma is a devastating brain cancer marked by its relapsing pattern and lack of effective chemotherapies. This shortage of treatments is due to limited knowledge about ependymoma tumorigenic mechanisms. By means of single-nucleus chromatin
Rachael G. Aubin +6 more
semanticscholar +1 more source

