Results 11 to 20 of about 274,722 (228)

Food allergy: Epicutaneous immunotherapy. [PDF]

J Food Allergy, 2020
The goal of allergen-specific immunotherapy for treatment of immunoglobulin E (IgE) mediated food allergy is to safely and effectively modify the allergic response, providing protection against anaphylaxis via ongoing exposure to the triggering allergen.
Chow TG, Parrish C, Bird JA.
europepmc   +3 more sources

Epicutaneous immunotherapy protects cashew-sensitized mice from anaphylaxis. [PDF]

Allergy, 2021
AbstractBackgroundThe prevalence of tree nut allergy has increased worldwide, and cashew has become one of the most common food allergens. More critically, cashew allergy is frequently associated with severe anaphylaxis. Despite the high medical need, no approved treatment is available and strict avoidance and preparedness for prompt treatment of ...
Pelletier B, Perrin A, Assoun N, Plaquet C, Oreal N, Gaulme L, Bouzereau A, Labernardière JL, Ligouis M, Dioszeghy V, Wavrin S, Matthews K, Porcheray F, Sampson HA, Hervé PL.   +14 more
europepmc   +4 more sources

Transitioning from epicutaneous to oral peanut immunotherapy

Frontiers in Allergy, 2023
IntroductionEpicutaneous immunotherapy (EPIT) has been tested in clinical trials for children with peanut allergy (PA) for its safety and efficacy in inducing desensitization.
Lauren Wong, Laurie Kost, Brent Anderson, Andrew Long, Sayantani B. Sindher, R. Sharon Chinthrajah, William J. Collins, William J. Collins   +7 more
doaj   +3 more sources

Efficacy and safety of peanut epicutaneous immunotherapy in patients with atopic comorbidities. [PDF]

J Allergy Clin Immunol Glob, 2023
Background Co-occurring atopic conditions are common in children with peanut allergy. As such, it is important to examine the safety and efficacy of epicutaneous immunotherapy with Viaskin Peanut 250 μg patch (VP250) in peanut-allergic children with ...
Davis CM, Lange L, Beyer K, Fleischer DM, Ford L, Sussman G, Oriel RC, Pongracic JA, Shreffler W, Bee KJ, Campbell DE, Green TD, Lambert R, Peillon A, Bégin P.   +14 more
europepmc   +2 more sources

Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy [PDF]

Allergy, 2020
IgE‐mediated food allergy remains a significant and growing problem across the globe. Of the various treatment modalities, oral immunotherapy (OIT) and epicutaneous immunotherapy (EPIT) have been the best studied.
Edwin H. Kim, A. Burks
semanticscholar   +3 more sources

Epicutaneous Immunotherapy for Aeroallergen and Food Allergy. [PDF]

Curr Treat Options Allergy, 2014
IgE-mediated allergies today affect up to 30 % of the population in industrialized countries. Allergen immunotherapy is the only disease-modifying treatment option with a long-term effect. However, very few patients (
Senti G, von Moos S, Kündig TM.
europepmc   +4 more sources

Laser-facilitated epicutaneous immunotherapy to IgE-mediated allergy. [PDF]

J Control Release, 2016
Allergen specific immunotherapy has been shown to be the only effective treatment for long-lasting clinical benefit to IgE-mediated allergic diseases, but a fewer than 5% of patients choose the treatment because of inconvenience and a high risk of anaphylaxis.
Kumar MNK, Zhou C, Wu MX.
europepmc   +4 more sources

Varying Doses of Epicutaneous Immunotherapy With Viaskin Milk vs Placebo in Children With Cow's Milk Allergy: A Randomized Clinical Trial.

JAMA Pediatr
This randomized clinical trial assesses dose, efficacy, and safety of epicutaneous immunotherapy with Viaskin Milk in children with immunoglobulin E-mediated cow’s milk allergy.
Petroni D, Bégin P, Bird JA, Brown-Whitehorn T, Chong HJ, Fleischer DM, Gagnon R, Jones SM, Leonard S, Makhija MM, Oriel RC, Shreffler WG, Sindher SB, Sussman GL, Yang WH, Bee KJ, Bois T, Campbell DE, Green TD, Rutault K, Sampson HA, Wood RA.   +21 more
europepmc   +2 more sources

Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice [PDF]

Clinical and Translational Allergy, 2012
Background Epicutaneous immunotherapy (EPIT) on intact skin with an epicutaneous delivery system has already been used in preclinical and clinical studies.
Mondoulet Lucie, Dioszeghy Vincent, Puteaux Emilie, Ligouis Mélanie, Dhelft Véronique, Letourneur Franck, Dupont Christophe, Benhamou Pierre-Henri   +7 more
doaj   +2 more sources

Delivery of allergen powder for safe and effective epicutaneous immunotherapy. [PDF]

J Allergy Clin Immunol, 2020
More effective and safer immunotherapies to manage peanut allergy are in great demand despite extensive investigation of sublingual/oral immunotherapy and epicutaneous immunotherapy (EPIT) currently in the clinics.We sought to develop a powder-laden, dissolvable microneedle array (PLD-MNA) for epidermal delivery of powdered allergens and to evaluate ...
Yu Y, Kiran Kumar MN, Wu MX.
europepmc   +4 more sources