Results 51 to 60 of about 256,445 (134)

A Systematic Review and Meta‐Analysis on the Induction of Confirmed Eosinophilic Esophagitis as a Side Effect of Allergen Immunotherapy: An EAACI Task Force Report

Allergy, EarlyView.
ABSTRACT The European Academy of Allergy and Clinical Immunology (EAACI) established a Task Force to assess the existing data on the relationship between eosinophilic esophagitis (EoE) and allergen immunotherapy (AIT). This systematic review and meta‐analysis aimed to study the incidence of confirmed EoE, developing as a side effect of AIT to food or ...
Carlo Maria Rossi, Ingrid Terreehorst, Evaggelia Apostolidou, Martina Votto, Arzu Bakirtas, Antonella Cianferroni, George N. Konstantinou, Katerina Pantavou, Dario Antolin‐Amerigo, Enrico Heffler, Alberto Alvarez‐Perea, Montserrat Fernandez‐Rivas, Georgios K. Nikolopoulos, Oliver Pfaar, Constantinos Pitsios   +14 more
wiley   +1 more source

Therapeutic perspectives in food allergy

Journal of Translational Medicine, 2020
Background In the last twenty years, several studies have been conducted in the search for new therapeutic strategies in patients with food allergy; in particular, after the failure of injection immunotherapy, three different routes of administration ...
Francesco Marcucci, Chiara Isidori, Alberto Argentiero, Cosimo Neglia, Susanna Esposito   +4 more
doaj   +1 more source

Sequence of Immunological Events During IgE‐Mediated Allergic Reactions to Food

Allergy, EarlyView.
ABSTRACT Food allergies (FA) represent a significant global health burden. Upon allergen re‐exposure, allergic patients exhibit a sequence of symptoms that vary in terms of affected organ systems, severity, time of onset and allergen reactivity thresholds.
N. A. Nagy, D. Schnoegl, V. Houghton, L. O'Mahony, A. F. Santos, E. F. Knol, A. Kuehn, T. Eiwegger   +7 more
wiley   +1 more source

Immunotherapy for food allergy: current proposals to improve safety and efficacy

Pediatric Respirology and Critical Care Medicine
This review mainly focuses on the novel approaches that improve the safety and efficacy of immunotherapies, namely SLIT [alone or as pre-treatment of oral immunotherapy (OIT)], epicutaneous immunotherapy (EPIT), combination of anti-IgE into OIT or ...
Wing Tung Crystal Wan
doaj   +1 more source

Update on clinical research for food allergy treatment

Frontiers in Allergy, 2023
The incidence of IgE-mediated food allergy (FA) has continued to increase over the years which places substantial burden on patient health and quality of life. With no cure for this disease, the mainstay of management has been allergen avoidance. However,
Joshua Fowler, Jay Lieberman
doaj   +1 more source

Randomised, Double‐Blinded, Placebo‐Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions

Veterinary Dermatology, EarlyView.
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Evi I. Sofou, Elisa Samuel, Svetlina Aleksandrova, Manolis Chatzis, Manolis N. Saridomichelakis   +4 more
wiley   +1 more source

Long-Term, Open-Label Extension Study of the Efficacy and Safety of Epicutaneous Immunotherapy for Peanut Allergy in Children: PEOPLE 3-Year Results.

Journal of Allergy and Clinical Immunology, 2020
BACKGROUND We previously reported the safety and efficacy of epicutaneous immunotherapy (EPIT™) for peanut allergy (250 μg, daily epicutaneous peanut protein; DBV712 250μg) in a 12-month randomized controlled study (PEPITES) of peanut-allergic children ...
D. Fleischer, W. Shreffler, Dianne E. Campbell, Dianne E. Campbell, Todd D. Green, Todd D. Green, S. Anvari, S. Anvari, A. Assa'ad, P. Bégin, K. Beyer, J. Bird, T. Brown-whitehorn, T. Brown-whitehorn, A. Byrne, E. Chan, A. Cheema, S. Chinthrajah, H. Chong, C. Davis, Lara S. Ford, Lara S. Ford, R. Gagnon, M. Greenhawt, J. Hourihane, J. Hourihane, S. Jones, Edwin H. Kim, L. Lange, B. Lanser, Stephanie A. Leonard, Stephanie A. Leonard, V. Mahler, A. Maronna, A. Nowak‐Wegrzyn, R. Oriel, M. O'Sullivan, D. Petroni, J. Pongracic, S. L. Prescott, S. L. Prescott, L. Schneider, Peter Smith, D. Staab, G. Sussman, R. Wood, William H. Yang, R. Lambert, A. Peillon, T. Bois, Hugh A. Sampson, Hugh A. Sampson   +51 more
semanticscholar   +1 more source

Heat‐treated egg allergens show lower basophil activation: A path toward safer oral immunotherapy

Pediatric Allergy and Immunology, Volume 37, Issue 1, January 2026.
Abstract Background Oral immunotherapy (OIT) is a promising approach for treating IgE‐mediated food allergy, but safety concerns limit its use. Heat‐denaturation of food allergens may reduce allergic reactions by lowering IgE binding. Here, we examined how heat‐induced structural changes in egg allergens affected basophil activation in egg‐allergic ...
Marta Paolucci, Maria Breiding, Macsmeila Dietrich, Jana G. Meyer, Agathe Duda, Alice Köhli, Claudia C. V. Lang, Sayeh Agah, Sabina Wuenschmann, Klaus Eyer, Thomas M. Kündig, Johannes Trück, Pål Johansen   +12 more
wiley   +1 more source

Immunotherapy for Food Allergy: Myth or Reality?

Jurnal Penyakit Dalam Indonesia, 2019
Allergic reaction to food can have serious consequences. The only treatment option is strict allergen avoidance, but accidental ingestions happen frequently and can lead to severe and potentially life-threatening allergic reactions.
Gatot Soegiarto
doaj   +1 more source

Food allergy immunotherapy: Oral immunotherapy and epicutaneous immunotherapy

Allergy. European Journal of Allergy and Clinical Immunology, 2020
IgE‐mediated food allergy remains a significant and growing problem across the globe. Of the various treatment modalities, oral immunotherapy (OIT) and epicutaneous immunotherapy (EPIT) have been the best studied.
Edwin H. Kim, A. Burks
semanticscholar   +1 more source