Results 1 to 10 of about 677 (127)

Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice. [PDF]

PLoS ONE, 2012
BackgroundFood allergy may affect the gastrointestinal tract and eosinophilia is often associated with allergic gastrointestinal disorders. Allergy to peanuts is a life-threatening condition and effective and safe treatments still need to be developed ...
Lucie Mondoulet, Vincent Dioszeghy, Thibaut Larcher, Mélanie Ligouis, Véronique Dhelft, Emilie Puteaux, Yan Cherel, Franck Letourneur, Christophe Dupont, Pierre-Henri Benhamou   +9 more
doaj   +14 more sources

Intact skin and not stripped skin is crucial for the safety and efficacy of peanut epicutaneous immunotherapy (EPIT) in mice [PDF]

Clinical and Translational Allergy, 2012
Background Epicutaneous immunotherapy (EPIT) on intact skin with an epicutaneous delivery system has already been used in preclinical and clinical studies.
Mondoulet Lucie, Dioszeghy Vincent, Puteaux Emilie, Ligouis Mélanie, Dhelft Véronique, Letourneur Franck, Dupont Christophe, Benhamou Pierre-Henri   +7 more
doaj   +7 more sources

Predicted number of peanut-allergic patients needed to treat with epicutaneous immunotherapy (EPIT) to prevent one allergic reaction: A novel approach to assessing relevance. [PDF]

Allergy, 2021
Letter to the editor about the predicted number of peanut-allergic patients needed to treat with epicutaneous immunotherapy (EPIT) to prevent one allergic reaction, including a novel approach to assessing relevance.
Remington BC, Koppelman SJ, Green TD, Lack G, Roberts G, Campbell DE.   +5 more
europepmc   +9 more sources

Efficacy of epicutaneous immunotherapy (EPIT) in a new model of peanut-induced eosinophilic esophagitis (EoE) and allergic enterpathy (AE) [PDF]

Clin Transl Allergy, 2011
Background Eosinophilia is often linked to allergic gastrointestinal disorders linked to food allergy. EPIT using Viaskin® device has been described as a therapeutic method in food allergy. We developed a model of mice sensitized to peanut, exhibiting EoE and AE after exclusive feeding with peanut protein extracts (PPE).
Mondulet L, Dioszeghy V, Dhelft V, Ligouis M, Puteaux E, Larcher T, Cherel Y, Dupont C, Benhamou P.   +8 more
europepmc   +9 more sources

Innovative delivery systems for epicutaneous immunotherapy [PDF]

Frontiers in Immunology, 2023
Allergen-specific immunotherapy (AIT) describes the establishment of peripheral tolerance through repeated allergen exposure, which qualifies as the only curative treatment for allergic diseases.
Zhen Wang, Lingzhi Wu, Wei Wang
doaj   +5 more sources

Improvements in Quality of Life in Children Following Epicutaneous Immunotherapy (EPIT) for Peanut Allergy in the PEPITES and PEOPLE Studies [PDF]

The Journal of Allergy and Clinical Immunology: In Practice, 2020
Food allergy quality of life (FAQL) is impaired in children with peanut allergy. Food Allergy Quality of Life Questionnaires (FAQLQs) provide disease-specific insight into the burden of peanut allergy and potential FAQL changes after peanut immunotherapy.To examine FAQL changes in children after treatment with epicutaneous immunotherapy for peanut ...
Audrey DunnGalvin, David M. Fleischer, Dianne E. Campbell, Jonathan O’B Hourihane, Todd D. Green, Hugh A. Sampson, Matthew Greenhawt   +6 more
core   +7 more sources

Epithelial immunotherapy for food allergy in children: a systematic review and meta-analysis [PDF]

Frontiers in Immunology
ObjectivesTraditional methods of treating allergies primarily revolve around avoiding allergens and promptly using rescue medications when allergic symptoms occur. However, this approach is known for its inefficiency and limited success in achieving long-
Bin Chen, Bin Chen, Hu Gao, Hu Gao, Xihong Li, Xihong Li, Zhuan Zou, Zhuan Zou, Shanshan Wu, Shanshan Wu, Fajuan Tang, Fajuan Tang   +11 more
doaj   +5 more sources

Anti-IgE therapy versus allergen-specific immunotherapy for food allergy: weighing the pros and cons [PDF]

Frontiers in Immunology
With the recent FDA approval of the anti-IgE biologic, omalizumab, in 2024 for the treatment of food allergy, it is critical to consider the advantages and disadvantages of anti-IgE and allergen-specific immunotherapies (AITs) to help determine optimal ...
Michael D. Kulis, Jessica R. Humphrey, James W. Krempski, Edwin H. Kim, Johanna M. Smeekens, Johanna M. Smeekens   +5 more
doaj   +5 more sources

Therapeutic perspectives in food allergy [PDF]

Journal of Translational Medicine, 2020
Background In the last twenty years, several studies have been conducted in the search for new therapeutic strategies in patients with food allergy; in particular, after the failure of injection immunotherapy, three different routes of administration ...
Francesco Marcucci, Chiara Isidori, Alberto Argentiero, Cosimo Neglia, Susanna Esposito   +4 more
doaj   +3 more sources

Recent advances in epicutaneous immunotherapy and potential applications in food allergy [PDF]

Frontiers in Allergy, 2023
Given the potent immunological properties of the skin, epicutaneous immunotherapy (EPIT) emerges as a promising treatment approach for inducing immune tolerance, particularly for food allergies.
Pierre-Louis Hervé, Vincent Dioszeghy, Katie Matthews, Katharine J. Bee, Dianne E. Campbell, Dianne E. Campbell, Hugh A. Sampson   +6 more
doaj   +2 more sources