Epicutaneous immunotherapy for food allergy: A systematic review and meta‐analysis [PDF]
Background Food allergies pose a global healthcare challenge, underscoring the need for effective interventions. This study evaluated the efficacy and safety of epicutaneous immunotherapy (EPIT) for food allergen desensitisation.
Péter Csonka, Bohee Lee, Ilari Kuitunen
doaj +5 more sources
EAACI guidelines on the management of IgE-mediated food allergy. [PDF]
This European Academy of Allergy and Clinical Immunology (EAACI) guideline provides recommendations for the management of IgE-mediated food allergy and was developed using the Grading of Recommendations, Assessment, Development and Evaluations (GRADE ...
Santos AF +63 more
europepmc +9 more sources
Estimated risk reduction to packaged food reactions by epicutaneous immunotherapy (EPIT) for peanut allergy [PDF]
Peanut allergy is a generally persistent, sometimes life-threatening food allergy. With no treatments demonstrating the ability to cure a food allergy, the focus of drugs in development has been on providing a level of protection against accidental exposure reactions.
Benjamin C. Remington +7 more
openalex +6 more sources
Estimated Risk Reduction to Packaged Food Reactions by Epicutaneous Immunotherapy (EPIT) for Peanut Allergy [PDF]
B Remington, T Krone, E Kim. Ann Allergy Asthma Immunol . 2019;123(5):488–493.e2 To estimate the relative risk reduction (RRR) when consuming peanut-contaminated packaged food products in children treated with epicutaneous immunotherapy (EPIT) for 12 months versus placebo.
Michael Tomani, Theresa Bingemann
openalex +2 more sources
The safety and efficacy of oral immunotherapy compared to epicutaneous immunotherapy in peanut allergen desensitisation amongst the paediatric cohort—a narrative review [PDF]
Peanut allergies result from a type 1 hypersensitivity reaction, with a prevalence of approximately 1% in children under 5 years of age. The allergens that instigate this reaction are the peanut proteins (Ara h 1–Ara h 8) for which IgE antibodies are ...
Ehtesam A. Chowdhury, Olivia C. Jadeja
doaj +2 more sources
Treatment of eosinophilic gastritis by epicutaneous immunotherapy (EPIT) in peanut allergic piglets [PDF]
Treatment of eosinophilic gastritis by epicutaneous immunotherapy (EPIT) in peanut allergic piglets.
Lucie Mondoulet +7 more
+6 more sources
Antigen Uptake by Langerhans Cells Is Required for the Induction of Regulatory T Cells and the Acquisition of Tolerance During Epicutaneous Immunotherapy in OVA-Sensitized Mice [PDF]
The skin is a major immunologic organ that may induce protection, sensitization or tolerance. Epicutaneous immunotherapy (EPIT) has been proposed as an attractive strategy to actively treat food allergy and has been shown to induce tolerance in ...
Vincent Dioszeghy +7 more
doaj +3 more sources
Transitioning from epicutaneous to oral peanut immunotherapy [PDF]
IntroductionEpicutaneous immunotherapy (EPIT) has been tested in clinical trials for children with peanut allergy (PA) for its safety and efficacy in inducing desensitization.
Lauren Wong +7 more
doaj +2 more sources
Update on clinical research for food allergy treatment [PDF]
The incidence of IgE-mediated food allergy (FA) has continued to increase over the years which places substantial burden on patient health and quality of life. With no cure for this disease, the mainstay of management has been allergen avoidance. However,
Joshua Fowler, Jay Lieberman
doaj +2 more sources
Probiotics and other adjuvants in allergen-specific immunotherapy for food allergy: a comprehensive review [PDF]
This review delves into the potential of manipulating the microbiome to enhance oral tolerance in food allergy, focusing on food allergen-specific immunotherapy (FA-AIT) and the use of adjuvants, with a significant emphasis on probiotics.
Maurizio Mennini +11 more
doaj +2 more sources

