Results 41 to 50 of about 696 (142)
Current developments in the treatment of peanut allergy [PDF]
, 2021 Peanut allergy is a potentially life-threatening disease because it leads to severe allergic reactions, especially in children but also in adults. So far, allergen avoidance is the most effective therapy for treating peanut allergy.
Alexiou, Aikaterina +4 more
core +1 more source
Innovative Systems to Deliver Allergen Powder for Epicutaneous Immunotherapy
Frontiers in Immunology, 2021 Allergy is a disorder owing to hyperimmune responses to a particular kind of substance like food and the disease remains a serious healthcare burden worldwide.
Yensheng Wang, Yifei Kong, Mei X. Wu
doaj +1 more source
Immune response evolution in peanut epicutaneous immunotherapy for peanut‐allergic children
Allergy, Volume 78, Issue 9, Page 2467-2476, September 2023., 2023 This phase 3 double‐blind placebo‐controlled food challenge examined serum‐specific IgG4 and IgE (whole peanut and components) in the subjects enrolled in Efficacy and Safety of Viaskin Peanut in Children With IgE‐Mediated Peanut Allergy study. Among 4‐ to 11‐year‐old participants, peanut‐specific IgG4 levels could distinguish DBV712‐treated subjects ...
Marie Bastin +10 more
wiley +1 more source
An update on recent developments and highlights in food allergy
Allergy, Volume 78, Issue 9, Page 2344-2360, September 2023., 2023 Abstract While both the incidence and general awareness of food allergies is increasing, the variety and clinical availability of therapeutics remain limited. Therefore, investigations into the potential factors contributing to the development of food allergy (FA) and the mechanisms of natural tolerance or induced desensitization are required.
Arielle Locke +5 more
wiley +1 more source
Clinical & Translational Immunology, 2021 Objective There are no disease‐modifying therapies for the treatment of eosinophilic oesophagitis (EoE), which is driven by non‐IgE‐mediated allergic inflammation.
Melanie A Ruffner +6 more
doaj +1 more source
New routes for allergen immunotherapy [PDF]
, 2012 IgE-mediated allergy is a highly prevalent disease in the industrialized world. Allergen-specific immunotherapy (SIT) should be the preferred treatment, as it has long lasting protective effects and can stop the progression of the disease.
Johansen, Pål +4 more
core +1 more source
Peanut allergy burden survey: Factors associated with health‐related quality of life in adolescents
Clinical and Translational Allergy, Volume 13, Issue 3, March 2023., 2023 Abstract Background Patients with peanut allergy (PA) experience significant burden of illness, which impacts health‐related quality of life (HRQoL), particularly in adolescence. There is a paucity of research evaluating drivers of HRQoL scores. Methods A prospective, online survey of adolescents with self‐reported, provider‐diagnosed PA completed from
William A. McCann +4 more
wiley +1 more source
EAACI Molecular Allergology User's Guide 2.0
Pediatric Allergy and Immunology, Volume 34, Issue S28, March 2023., 2023 Abstract Since the discovery of immunoglobulin E (IgE) as a mediator of allergic diseases in 1967, our knowledge about the immunological mechanisms of IgE‐mediated allergies has remarkably increased. In addition to understanding the immune response and clinical symptoms, allergy diagnosis and management depend strongly on the precise identification of ...
Stephanie Dramburg +100 more
wiley +1 more source
No impact of filaggrin deficiency on the efficacy of epicutaneous immunotherapy in a murine model
AIMS Allergy and Immunology, 2017 Background: Epicutaneous immunotherapy (EPIT®), currently investigated in the treatment of food allergy, needs the integrity of the skin to warrant safety and efficacy. Mutations in the gene encoding the key epidermal protein filaggrin (FLG) are risk
Lucie Mondoulet +8 more
doaj +1 more source
Frontiers in Immunology, 2021 Due to its richness in antigen presenting cells, e.g., dendritic cells (DC), the skin has been identified as a promising route for immunotherapy and vaccination.
Pierre-Louis Hervé +10 more
doaj +1 more source