Results 41 to 50 of about 826,967 (302)

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Impacts of epidemic outbreaks on supply chains: mapping a research agenda amid the COVID-19 pandemic through a structured literature review

Annals of Operations Research, 2020
The coronavirus (COVID-19) outbreak shows that pandemics and epidemics can seriously wreak havoc on supply chains (SC) around the globe. Humanitarian logistics literature has extensively studied epidemic impacts; however, there exists a research gap in ...
M. Queiroz, D. Ivanov, A. Dolgui, S. Wamba   +3 more
semanticscholar   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Why were so few randomized trials of public health and social measures conducted during the COVID-19 pandemic? The Norwegian experience

Trials
Background Few randomized trials of public health and social measures were carried out during the COVID-19 pandemic. We report on the major barriers we faced when we tried to run such trials.
Atle Fretheim, Petter Elstrøm, Cathinka Halle Julin, Unni Gopinathan, Ingeborg Hess Elgersma, Runar Barstad Solberg, Arnfinn Helleve   +6 more
doaj   +1 more source

Epidemic characteristics of food poisonings in Yunnan province, 2004 – 2019

Zhongguo gonggong weisheng, 2022
ObjectiveTo explore epidemic characteristics of food poisonings reported in Yunnan province and to provide evidences for developing strategies on the prevention and control of food poisoning.MethodsFrom the Public Health Emergency Reporting System, a ...
Xiu-lian SHEN, Shan-hua YANG, Xia PENG
doaj   +1 more source

Asymmetry of the Ferroelectric Phase Transition in BaTiO3

Advanced Materials, EarlyView.
Phase transitions are typically assumed to behave identically in forward and reverse. This work shows that in the ferroelectric material barium titanate this is not true: heating drives an abrupt, first‐order jump, while cooling gives a smooth, continuous change.
Asaf Hershkovitz, Elangovan Hemaprabha, Rajesh Mandal, Pravin Kavle, Jamil Tanus, Maya Barzilay, Ching‐Che Lin, David Spirito, Semën Gorfman, Bo Wang, Ignacio J. Villar‐García, Neus Domingo, Long‐Qing Chen, Lane W. Martin, Yachin Ivry   +14 more
wiley   +1 more source

The Psychological Impact of Epidemic and Pandemic Outbreaks on Healthcare Workers: Rapid Review of the Evidence

Current Psychiatry Reports, 2020
Purpose of Review We aim to provide quantitative evidence on the psychological impact of epidemic/pandemic outbreaks (i.e., SARS, MERS, COVID-19, ebola, and influenza A) on healthcare workers (HCWs).
E. Preti, V. D. Di Mattei, G. Perego, Federica Ferrari, M. Mazzetti, P. Taranto, Rossella Di Pierro, F. Madeddu, R. Calati   +8 more
semanticscholar   +1 more source

Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Advanced Materials Technologies, Volume 10, Issue 6, March 18, 2025.
This review focuses on the application of synthetic biodegradable microarray patches (MAPs) in sustained drug delivery. Compared to conventional MAPs which release drugs into the skin in an immediate manner, these implantable MAPs release drugs into skin microcirculation gradually as the biodegradable polymers degrade, thus offering sustained release ...
Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta, Ryan F. Donnelly   +6 more
wiley   +1 more source

Integration of a social network strategy into index testing to increase HIV case finding among Haitian migrants and their descendants in the Dominican Republic

BMC Infectious Diseases
Introduction Increasing effectiveness, efficiency, and reach of HIV case-finding strategies among priority populations is essential for epidemic control.
Caterina Casalini, Molly Goggin-Kehm, Jacob Michel, Roudy Joseph, Ruth Diaz, Gianmarco Martinez, Stevenson Saint-Hilaire, Gercy Mateo, Chris Akolo, Navindra Persaud, Natasha Mack, Katherine Hernandez, Mario Reyes, Ceida Martinez, Leidy Tamarez, Mayra Elizardi, Maria Garcia, Algeni Lorenzo, Johana Molil, Elvis Baez, Rebecca Fertziger, Alejandro Soto   +21 more
doaj   +1 more source

Epidemiological characteristics and outbreak management of influenza in Yunnan province, 2010 – 2021

Zhongguo gonggong weisheng, 2023
ObjectiveTo analyze epidemiological characteristics and outbreak management of influenza in Yunnan province and to provide evidence for developing effective prevention and control strategies.
Xiulian SHEN, Erda ZHENG, Tian HUANG, Yuchen JIA, Jibo HE, Xia PENG   +5 more
doaj   +1 more source