Results 151 to 160 of about 2,162,697 (423)

Approaching heterogeneity of human epidermal growth factor receptor 2 in surgical specimens of gastric cancer. [PDF]

open access: yes, 2012
Summary Gastric cancer shows intratumoral heterogeneity for human epidermal growth factor receptor 2 expression. We evaluated whether the number of tissue blocks analyzed or the antibodies used may influence the immunohistochemical results in gastrectomy
Asioli, Sofia   +13 more
core   +1 more source

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

open access: yesFEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran   +3 more
wiley   +1 more source

Epidermal growth factor receptor: Role in human cancer

open access: yesIndian Journal of Dental Research, 2017
Cells are constantly exposed to various external stimuli which regulate the growth and survival of the cells. The signal transduction from the external environment to the interior of the cell is carried out by cell surface or transmembrane receptors ...
Prashanth Rajaram   +5 more
doaj   +1 more source

Screening for epidermal growth factor receptor mutations in lung cancer.

open access: yesNew England Journal of Medicine, 2009
BACKGROUND Activating mutations in the epidermal growth factor receptor gene (EGFR) confer hypersensitivity to the tyrosine kinase inhibitors gefitinib and erlotinib in patients with advanced non-small-cell lung cancer.
R. Rosell   +27 more
semanticscholar   +1 more source

Memory effects in biochemical networks as the natural counterpart of extrinsic noise [PDF]

open access: yesarXiv, 2014
We show that in the generic situation where a biological network, e.g. a protein interaction network, is in fact a subnetwork embedded in a larger "bulk" network, the presence of the bulk causes not just extrinsic noise but also memory effects. This means that the dynamics of the subnetwork will depend not only on its present state, but also its past ...
arxiv  

Keratinocyte stimulation of matrix metalloproteinase-1 production and proliferation in fibroblasts: regulation through mitogen-activated protein kinase signalling events [PDF]

open access: yes
Incubation of human dermal fibroblasts in keratinocyte-conditioned culture medium led to a 5.7-fold increase in the level of matrix metalloproteinase-1.
Bhagavathula, N, Moon, S E, Varani, J
core   +2 more sources

Efficacy of topical recombinant epidermal growth factor as compared to Povidone Iodine on chronic diabeic foot ulcers [PDF]

open access: yes, 2020
Background: Diabetic foot ulcer is a common surgical complication in patient of diabetes mellitus. It is the most frequent reason for hospitalization for patients with diabetes.
Khandelwal, Bhavesh   +2 more
core   +1 more source

Murine Models and Human Cell Line Models to Study Altered Dynamics of Ovarian Follicles in Polycystic Ovary Syndrome

open access: yesAdvanced Biology, EarlyView.
The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua   +5 more
wiley   +1 more source

Effect of Recombinant Human Epidermal Growth Factor Impregnated Chitosan Film on Hemostasis and Healing of Blood Vessels

open access: yesArchives of Plastic Surgery, 2014
Background Bleeding can be a problem in wound debridement. In search for an effective hemostatic agent, we experimented with a chitosan film combined with the recombinant human epidermal growth factor (rh-EGF), hypothesizing that it would achieve ...
Sangshin Lee   +3 more
doaj   +1 more source

Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry.

open access: yesJournal of Clinical Oncology, 2005
PURPOSE To establish evidence of activity, or lack thereof, of cetuximab-based therapy in patients with refractory colorectal cancer with tumors that do not demonstrate epidermal growth factor receptor (EGFR) expression by immunohistochemistry (IHC ...
K. Chung   +13 more
semanticscholar   +1 more source

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