The Antimicrobial Peptide LL-37 Activates Innate Immunity at the Airway Epithelial Surface by Transactivation of the Epidermal Growth Factor Receptor [PDF]
, 2003 G. Sandra Tjabringa +7 more
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Role of Epidermal Growth Factor Receptor (EGFR) and Its Ligands in Kidney Inflammation and Damage [PDF]
, 2018 Chronickidneydisease (CKD)ischaracterized bypersistent inflammationandprogressive fibrosis,ultimatelyleadingto end-stage renal disease. Although many studies have investigated the factors involved in the progressive deterioration of renal function, current
Goldschmeding, Roel +6 more
core +2 more sources
Wearable Haptic Feedback Interfaces for Augmenting Human Touch
Advanced Functional Materials, EarlyView.The wearable haptic feedback interfaces enhance user experience in gaming, social media, biomedical instrumentation, and robotics by generating tactile sensations. This review discusses and categorizes current haptic feedback interfaces into force, thermal, and electrotactile stimulation‐based haptic feedback interfaces, elucidating their current ...
Shubham Patel +3 more
wiley +1 more source
Versatile Cell Penetrating Peptide for Multimodal CRISPR Gene Editing in Primary Stem Cells
Advanced Functional Materials, EarlyView.CRISPR machinery in diverse molecular formats (DNA, RNA, and ribonucleic protein) is complexed into nanoparticles with the cell‐friendly arginine‐alanine‐leucine‐alanine (RALA) cell‐penetrating peptide. Nanoparticles are delivered to primary mesenchymal stem cells ex vivo or locally in vivo to facilitate multimodal CRISPR gene editing. This RALA‐CRISPR
Joshua P. Graham +9 more
wiley +1 more source
International Journal of Women's Health, 2014 Nathan WD Lamond, Tallal YounisDepartment of Medicine, Dalhousie University at the Queen Elizabeth II Health Sciences Centre, Halifax, NS, CanadaAbstract: In the absence of specific therapy, the 15%–20% of breast cancers demonstrating human ...
Lamond NW, Younis T
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The Frequency of Epidermal Growth Factor Receptor (EGFR) Mutation in Patients with Lung Cancer Referred to the Lung Diseases Hospital; A Cross Sectional Study [PDF]
, 2021 Sotoudeh Mohammadi +8 more
openalex +1 more source
Machine Learning‐Enabled Polymer Discovery for Enhanced Pulmonary siRNA Delivery
Advanced Functional Materials, EarlyView.This study provides an efficient approach to train a machine learning model by merging heterogeneous literature data to predict suitable polymers for siRNA delivery. Without the need for extensive laboratory synthesis, the machine learning enabled a virtual screening and successfully predicted a polymer that is validated for effective gene silencing in
Felix Sieber‐Schäfer +10 more
wiley +1 more source
International Journal of Nanomedicine, 2014 Khaled Messaoudi,1 Patrick Saulnier,1 Kim Boesen,1 Jean-Pierre Benoit,1,2 Frederic Lagarce1,21L'Université Nantes Angers Le Mans, INSERM U1066, Micro et nanomédecines biomimétiques, Angers, France; 2Pharmacy Department, Angers ...
Messaoudi K +4 more
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Nanodiamond‐Infused Microgels for pH‐Tunable Rheology, Lubrication, and UV Protection
Advanced Functional Materials, EarlyView.Microgels consisting of swollen polyacrylic acid polymer networks, impregnated with nanodiamonds provide protection from ultraviolet (UV) radiation harmful to human health. Nanodiamonds enable UV blockage and control of the rheology (flow) and lubrication (skin‐feel) of these microgel‐skincare‐mimics.
Pallav K. Jani +10 more
wiley +1 more source
Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
Biologics: Targets & Therapy, 2009 Bryan A Faller, Barbara BurtnessDepartment of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USAAbstract: Pancreatic adenocarcinoma is a common malignancy that remains refractory to available therapies.
Bryan A Faller, Barbara Burtness
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