Advanced Functional Materials, EarlyView.Bio‐based and (semi‐)synthetic zwitterion‐modified novel materials and fully synthetic next‐generation alternatives show the importance of material design for different biomedical applications. The zwitterionic character affects the physiochemical behavior of the material and deepens the understanding of chemical interaction mechanisms within the ...
Theresa M. Lutz +3 more
wiley +1 more source
Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants
Molecules, 2016 The human Epidermal Growth Factor (EGFR) plays an important role in signaling pathways, such as cell proliferation and migration. Mutations like G719S, L858R, T790M, G719S/T790M or T790M/L858R can alter its conformation, and, therefore, drug responses ...
María Jesús García-Godoy +4 more
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Epidermal Growth Factor Receptor-mutated Lung Cancer as the Initial Manifestation of Germline TP53 Mutation Associated Cancer [PDF]
, 2018 Surabhi Pathak +3 more
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Advanced Functional Materials, EarlyView.This review explores functional and responsive materials for triboelectric nanogenerators (TENGs) in sustainable smart agriculture. It examines how particulate contamination and dirt affect charge transfer and efficiency. Environmental challenges and strategies to enhance durability and responsiveness are outlined, including active functional layers ...
Rafael R. A. Silva +9 more
wiley +1 more source
Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
Biologics: Targets & Therapy, 2009 Bryan A Faller, Barbara BurtnessDepartment of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USAAbstract: Pancreatic adenocarcinoma is a common malignancy that remains refractory to available therapies.
Bryan A Faller, Barbara Burtness
doaj
A Membrane Setting for the Sorting Motifs Present in the Adenovirus E3-13.7 Protein Which Down-regulates the Epidermal Growth Factor Receptor [PDF]
, 1998 Olga Vinogradova +3 more
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Advanced Functional Materials, EarlyView.A multifunctional nanodiamond platform enables pH‐triggered Diazoxide (DZX) delivery and quantum sensing of subcellular radical dynamics in triple‐negative breast cancer cells. Diamond relaxometry revealed reduced lysosomal radicals during DZX‐induced mitochondrial radical elevation, providing insights into redox modulation and organelle‐ resolved ...
Kaiqui Wu +8 more
wiley +1 more source
Research progress in targeted therapy for gastric cancer
Zhongguo linchuang yanjiuGastric cancer is a common malignant tumor worldwide, and its incidence rate and mortality have always been in the forefront. Most gastric cancer patients in China are diagnosed in the middle or late stages, with an unsatisfactory 5- year survival rate ...
WU Tengfei*, ZHAO Jinjin, LIN Jianxiu, TIAN Yun
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Immunohistochemical Characterization of Three Monoclonal Antibodies Raised against the Epidermal Growth Factor and Its Receptor in Non-Small-Cell Lung Cancer: Their Potential Use in the Selection of Patients for Immunotherapy [PDF]
, 2012 Charles E. Rengifo +5 more
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Advanced Functional Materials, EarlyView.A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker +16 more
wiley +1 more source