Results 151 to 160 of about 975,813 (425)

Magnetic Field‐Assisted Conductive Nerve Guidance Conduit Enabling Peripheral Nerve Regeneration with Wireless Electrical Stimulation

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces a conductive nerve guidance conduit integrated with wireless electrical stimulation through alternating magnetic fields, which induces currents and creates a supportive microenvironment for nerve regeneration. In vivo studies show that this approach significantly enhanced myelin restoration, gastrocnemius muscle regeneration ...
Shiheng Liu   +7 more
wiley   +1 more source

Pertuzumab in human epidermal growth-factor receptor 2-positive breast cancer: clinical and economic considerations

open access: yesInternational Journal of Women's Health, 2014
Nathan WD Lamond, Tallal YounisDepartment of Medicine, Dalhousie University at the Queen Elizabeth II Health Sciences Centre, Halifax, NS, CanadaAbstract: In the absence of specific therapy, the 15%–20% of breast cancers demonstrating human ...
Lamond NW, Younis T
doaj  

Molecular Docking Optimization in the Context of Multi-Drug Resistant and Sensitive EGFR Mutants

open access: yesMolecules, 2016
The human Epidermal Growth Factor (EGFR) plays an important role in signaling pathways, such as cell proliferation and migration. Mutations like G719S, L858R, T790M, G719S/T790M or T790M/L858R can alter its conformation, and, therefore, drug responses ...
María Jesús García-Godoy   +4 more
doaj   +1 more source

Development of a Three-Dimensional Multiscale Agent-Based Tumor Model: Simulating Gene-Protein Interaction Profiles, Cell Phenotypes & Multicellular Patterns in Brain Cancer [PDF]

open access: yesarXiv, 2006
Experimental evidence suggests that epidermal growth factor receptor (EGFR)-mediated activation of the signaling protein phospholipase C gamma plays a critical role in a cancer cell's phenotypic decision to either proliferate or to migrate at a given point in time. Here, we present a novel three-dimensional multiscale agent-based model to simulate this
arxiv  

Specific radiolabeling of a cell surface receptor for epidermal growth factor. [PDF]

open access: green, 1977
M Das   +5 more
openalex   +1 more source

Epidermal Growth Factor/Transforming Growth Factor Alpha Receptors and Psoriasis

open access: yesJournal of Investigative Dermatology, 1990
The abnormal growth and differentiation in psoriasis is reflected in the abnormal regulation of Epidermal Growth Factor/Transforming Growth Factor Alpha (EGF/TGFalpha) receptor metabolism. In psoriasis and other hyperproliferative skin conditions these receptors are persistently expressed throughout the interfollicular epidermis as long as the growth ...
Ronald E. Gates   +7 more
openaire   +3 more sources

Adjuvant Trastuzumab Therapy for Early HER2-Positive Breast Cancer in Iran: A Cost-Effectiveness and Scenario Analysis for an Optimal Treatment Strategy [PDF]

open access: yes, 2017
Introduction: Clinical guidelines have recommended a 1-year trastuzumab regimen as standard care for early human epidermal growth factor receptor 2 (HER2)-positive breast cancer; however ...
Ansaripour, A. (Amir)   +2 more
core   +4 more sources

Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease.

open access: yesJournal of Clinical Oncology, 2013
PURPOSE EGFR-mutant lung cancer was first described as a new clinical entity in 2004. Here, we present an update on new controversies and conclusions regarding the disease.
K. Ohashi, Y. Maruvka, F. Michor, W. Pao
semanticscholar   +1 more source

Wearable Haptic Feedback Interfaces for Augmenting Human Touch

open access: yesAdvanced Functional Materials, EarlyView.
The wearable haptic feedback interfaces enhance user experience in gaming, social media, biomedical instrumentation, and robotics by generating tactile sensations. This review discusses and categorizes current haptic feedback interfaces into force, thermal, and electrotactile stimulation‐based haptic feedback interfaces, elucidating their current ...
Shubham Patel   +3 more
wiley   +1 more source

Anti-epidermal growth factor receptor siRNA carried by chitosan-transacylated lipid nanocapsules increases sensitivity of glioblastoma cells to temozolomide

open access: yesInternational Journal of Nanomedicine, 2014
Khaled Messaoudi,1 Patrick Saulnier,1 Kim Boesen,1 Jean-Pierre Benoit,1,2 Frederic Lagarce1,21L'Université Nantes Angers Le Mans, INSERM U1066, Micro et nanomédecines biomimétiques, Angers, France; 2Pharmacy Department, Angers ...
Messaoudi K   +4 more
doaj  

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