Results 161 to 170 of about 975,813 (425)
Research progress in targeted therapy for gastric cancer
Zhongguo linchuang yanjiuGastric cancer is a common malignant tumor worldwide, and its incidence rate and mortality have always been in the forefront. Most gastric cancer patients in China are diagnosed in the middle or late stages, with an unsatisfactory 5- year survival rate ...
WU Tengfei*, ZHAO Jinjin, LIN Jianxiu, TIAN Yun
doaj +1 more source
Chiral Engineered Biomaterials: New Frontiers in Cellular Fate Regulation for Regenerative Medicine
Advanced Functional Materials, EarlyView.Chiral engineered biomaterials can selectively influence cell behaviors in regenerative medicine. This review covers chiral engineered biomaterials in terms of their fabrication methods, cellular response mechanisms, and applications in directing stem cell differentiation and tissue function.
Yuwen Wang +5 more
wiley +1 more source
Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
Biologics: Targets & Therapy, 2009 Bryan A Faller, Barbara BurtnessDepartment of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USAAbstract: Pancreatic adenocarcinoma is a common malignancy that remains refractory to available therapies.
Bryan A Faller, Barbara Burtness
doaj
Mitosis, Cytoskeleton Regulation, and Drug Resistance in Receptor Triple Negative Breast Cancer [PDF]
arXivDuring cell division, the receptor triple-negative MDA-MB-231 mitotic spindles are the largest in comparison to other BC cell lines. Many of the MDA-MB-231 spindles exhibit rapid lateral twisting during metaphase, which remains unaffected by knockdown of the oncogene Myc and treatment with inhibitors of the serine/threonine-protein kinase B-Raf and the
arxiv
Memory effects in biochemical networks as the natural counterpart of extrinsic noise [PDF]
arXiv, 2014 We show that in the generic situation where a biological network, e.g. a protein interaction network, is in fact a subnetwork embedded in a larger "bulk" network, the presence of the bulk causes not just extrinsic noise but also memory effects. This means that the dynamics of the subnetwork will depend not only on its present state, but also its past ...
arxiv
Advanced Functional Materials, EarlyView.Emulating nature's unparalleled engineering, this work introduces butterfly‐inspired hybrid composites for high‐performance transportation and defense sectors. Leveraging biomimicry, these lightweight composites feature butterfly leg‐inspired hierarchical fibrous assemblies and butterfly wing‐inspired sandwich‐structured architecture, to achieve ...
Nello D. Sansone +7 more
wiley +1 more source
Journal of Radiation and Cancer Research, 2017 Introduction: Head and neck cancer (HNC) has large worldwide prevalence and accounts for almost 5% among all types of cancers. Nimotuzumab is a humanized anti-epidermal growth factor receptor monoclonal antibody that has shown promising results in ...
Nagraj Gururaj Huilgol +3 more
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Molecular mechanism of mitogen action: Processing of receptor induced by epidermal growth factor [PDF]
, 1979 openalex +1 more source
Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line [PDF]
Over-expression of the adhesion molecule CD44 and its splice variants, especially CD44v6, is associated with poor prognosis and metastasis. We aimed at regulating the expression of CD44 in the highly metastatic human colon cancer cell line HM7 and ...
A Herrera-Gayol +30 more
core +2 more sources
Advanced Functional Materials, EarlyView.A hybrid‐nested microneedle/cryogel scaffold (MQW‐CMg‐MOF) is designed for efficient biofilm removal and accelerated healing of diabetic wounds. The scaffold shows substantial biofilm removal in vitro and in a preclinical diabetic swine biofilm‐infected wound model compared to the control.
Syed Muntazir Andrabi +11 more
wiley +1 more source