Results 341 to 350 of about 822,308 (398)

Increased Epidermal Growth Factor Receptor (EGFR) Associated with Hepatocyte Growth Factor (HGF) and Symptom Severity in Children with Autism Spectrum Disorders (ASDs)

Journal of Central Nervous System Disease, 2014
Anthony J. Russo
doaj  

The activity of pyrazoline B compound in inhibiting proliferation of breast cancer cells with human epidermal growth factor receptor 2 overexpression. [PDF]

Contemp Oncol (Pozn)
Satria D, Waruwu SB, Sholikhah EN, Mustofa M, Satriyo PB, Wahyuningsih TD, Wiraswati HL, Bashari MH, Damayanti E.   +8 more
europepmc   +1 more source

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Epidermal growth factor receptor: mechanisms of activation and signalling.

Experimental Cell Research, 2003
R. Jorissen, F. Walker, N. Pouliot, T. Garrett, C. Ward, A. Burgess   +5 more
semanticscholar   +2 more sources

Epidermal Growth Factor Receptor Mutations

Thoracic Surgery Clinics, 2020
Up to 20% of lung adenocarcinomas in the United States and Europe and 50% in Asia have activating mutations of the tyrosine kinase domain of the epidermal growth factor receptor (EGFR). The identification and subsequent targeting of mutations with EGFR-tyrosine kinase inhibitors (TKIs) led to significant advances in treatment of EGFR-mutant lung cancer.
Erin M, McLoughlin, Ryan D, Gentzler
openaire   +2 more sources

Review on Epidermal Growth Factor Receptor (EGFR) Structure, Signaling Pathways, Interactions, and Recent Updates of EGFR Inhibitors.

Current Topics in Medicinal Chemistry, 2020
The epidermal growth factor receptor (EGFR) belongs to ERBB family of tyrosine kinase receptor. EGFR signaling cascade is a key regulator in cell proliferation, differentiation, division, survival, and cancer development.
D. Sabbah, Rima Hajjo, K. Sweidan
semanticscholar   +1 more source

Epidermal growth factor receptors

Molecular and Cellular Biochemistry, 1981
EGF-Rs are cell membrane glycoproteins of wide distribution. They have not yet been fully characterized or purified but are probably molecules of 170-190,000 mol. wt. in most cells. The growth factor EGF binds and will saturate cell surface receptors with a KA of about 5 X 10(9) M-1 although a receptor class with an affinity in excess of 10(10) M-1 has
E D, Adamson, A R, Rees
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Phase III Randomized Study of Ribociclib and Fulvestrant in Hormone Receptor-Positive, Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: MONALEESA-3.

Journal of Clinical Oncology, 2018
Purpose This phase III study evaluated ribociclib plus fulvestrant in patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer who were treatment naïve or had received up to one line of prior ...
D. Slamon, P. Neven, S. Chia, P. Fasching, M. De Laurentiis, S. Im, K. Petráková, G. Bianchi, Francisco J. Esteva, Miguel Martín, A. Nusch, Gabe S Sonke, L. de la Cruz-Merino, J. Beck, X. Pivot, G. Vidam, Yingbo Wang, K. Rodriguez Lorenc, Michelle Miller, T. Taran, G. Jerusalem   +20 more
semanticscholar   +1 more source

Epidermal Growth Factor, Epidermal Growth Factor Receptors, Intestinal Growth, and Adaptation

Journal of Parenteral and Enteral Nutrition, 1999
Epidermal growth factor (EGF) is an important constituent of several gastrointestinal secretions. Many studies in both animals and humans have shown EGF to have multiple effects upon gut epithelial cells. These include cytoprotection, stimulatory effects on cell proliferation and migration, induction of gene expression such as mucosal enzymes and ...
W M, Wong, N A, Wright
openaire   +2 more sources