Results 41 to 50 of about 9,744,428 (293)

Molecular Targeting of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Receptor (VEGFR)

Molecules, 2021
Epidermal growth factor receptor (EGFR) and vascular endothelial growth factor receptor (VEGFR) are two extensively studied membrane-bound receptor tyrosine kinase proteins that are frequently overexpressed in many cancers.
Nichole E. M. Kaufman, Simran Dhingra, Seetharama D. Jois, Maria da Graça H. Vicente   +3 more
doaj   +1 more source

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients

Clinics, 2012
OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics.
Carlos E. Bacchi, Heloísa Ciol, Eduardo M. Queiroga, Lucimara C. Benine, Luciana H. Silva, Elida B. Ojopi   +5 more
doaj   +1 more source

miRNA-9 Inhibits Proliferation and Migration of Lung Squamous Cell Carcinoma Cells by Regulating NRSF/EGFR

Technology in Cancer Research & Treatment, 2020
Background: To investigate the mechanism of microRNA9 in inhibiting proliferation and migration of lung squamous cell carcinoma cells via neuron-restricted silencing factor/epidermal growth factor receptor.
Kangning Wang MD, Kai Xu MM, Xuefeng Leng MD, Yongtao Han BM, Qiang Fang MD   +4 more
doaj   +1 more source

Frequent Epidermal Growth Factor Receptor Gene Mutations in Malignant Pleural Effusion of Lung Adenocarcinoma

, 2011
Malignant pleural effusions (MPEs) are often observed in lung cancer, especially adenocarcinoma. Epidermal growth factor receptor (EGFR) gene mutations are usually detected in lung adenocarcinoma.
吳尚俊;高劍虹;余忠仁;張逸良;楊志新;施金元;李元麒;楊泮池, WU, SHANG-GIN;GOW, CHIEN-HUNG;YU, CHONG-JEN;CHANG, YIH-LEONG;YANG, CHIH-HSIN;SHIH, JIN-YUAN;LEE, YUNG-CHIE;YANG, PAN-CHYR   +1 more
core   +1 more source

The effect of distant metastases sites on survival in de novo stage-IV breast cancer: A SEER database analysis

Tumor Biology, 2017
To investigate the effect of distant metastases sites on survival in patients with de novo stage-IV breast cancer. From 2010 to 2013, patients with a diagnosis of de novo stage-IV breast cancer were identified using the Surveillance, Epidemiology, and ...
San-Gang Wu, Hui Li, Li-Ying Tang, Jia-Yuan Sun, Wen-Wen Zhang, Feng-Yan Li, Yong-Xiong Chen, Zhen-Yu He   +7 more
doaj   +1 more source

Analysis of Epithelial Growth Factor-Receptor (EGFR) Phosphorylation in Uterine Smooth Muscle Tumors [PDF]

, 2013
Uterine fibroids are the commonest uterine benign tumors. A potential mechanism of malignant transformation from leiomyomas to leiomyosarcomas has beendescribed.
Darius Dian, Antonis Makrigiannakis, Jeschke, Udo, Klaus Friese, Weissenbacher, Tobias, Mayr, Doris, David Roeder, Udo Jeschke, Nina Ditsch, Thomas Vrekoussis, Tobias Weissenbacher, Vrekoussis, Thomas, Dian, Darius, Ditsch, Nina, Friese, Klaus, Doris Mayr, Makrigiannakis, Antonis, Roeder, David   +17 more
core   +1 more source

Dynamic tracing for epidermal growth factor receptor mutations in urinary circulating DNA in gastric cancer patients

Tumor Biology, 2017
The mutations of epidermal growth factor receptor are detected in gastric cancer, indicating its suitability as a target for receptor tyrosine kinase inhibitors, as well as a marker for clinical outcome of chemotherapeutic treatments. However, extraction
Xiu-Qin Shi, Wen-Hua Xue, Song-Feng Zhao, Xiao-Jian Zhang, Wukong Sun   +4 more
doaj   +1 more source

A case of epidermal growth factor receptor tyrosine kinase inhibitor effectiveness in epidermal growth factor receptor mutation-positive squamous cell carcinoma

SAGE Open Medical Case Reports, 2023
A 71-year-old non-smoker woman was admitted to our hospital because of left front chest pain. A computed tomography scan showed a large mass of >7.0 cm in the lower left part of the lung and multiple organ metastases in the liver, brain, bone, and left ...
Sosuke Matsumura, Satoshi Ano, Norihiro Kikuchi, Michiko Masuda, Hajime Osawa, Yuzuru Kondo, Yukio Ishii, Nobuyuki Hizawa   +7 more
doaj   +1 more source

Clinicopathological Features and 10-Year Overall Survival Rate in Human Epidermal Growth Factor Receptor 2-Low Breast Cancer

Advanced Medical Journal
Background and Objectives: Human epidermal growth factor receptor 2-low breast cancers have garnered significant attention in oncology, particularly triple-negative breast cancer.
Didar Hamid, Hazha Mohammed
doaj   +1 more source

Epidermal Growth Factor Receptor Pathway [PDF]

Journal of Thoracic Oncology, 2010
The epidermal growth factor receptor (EGFR) pathway has provided a new therapeutic target in non-small cell lung cancer (NSCLC). Two EGFR tyrosine kinase inhibitors (TKIs) are being used globally as systemic treatment in advanced NSCLC. In addition, clinical observations with EGFR TKIS led to the discovery of EGFR activating mutations, which has ...
openaire   +2 more sources