Results 31 to 40 of about 334,289 (309)

THE PROGNOSTIC ROLE OF EPIDERMAL GROWTH FACTOR RECEPTOR MUTATION IN COMPLETELY RESECTED AMPULLARY ADENOCARCINOMA

, 2023
The aim of this study is to make a differential diagnosis and prognosis of the amp-ullary adenocarcinoma subtypes. We also investigated the role of prognostic mark-ers PD-1 and PD-L1, and epidermal growth factor receptor (EGFR). Local or locally advanced
Safiye Aktas, Somall, Isil, Salman, Tarik, Tarık Salman, Fatma Husniye Dilek, Cakir, Ebru, Aiacaciogiu, Ahmet, Varol, Umut, Ahmet Alacacioglu, Unlu, Ause Gulden Diniz, ALTUN, ZEKİYE SULTAN, Butun, Osman, Osman Butun, Ebru Cakır, Zekiye Sultan Altun, AKTAŞ, SAFİYE, Dilek, Fatma Husniye, Umut Varol, Ayse Gulden Diniz Unlu, Isil Somali   +19 more
core   +1 more source

Efficacy of Next-Generation EGFR-TKIs in Patients With Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials

Technology in Cancer Research & Treatment, 2020
Background: The efficacy of next-generation epidermal growth factor receptor-tyrosine kinase inhibitors in patients with advanced non-small cell lung cancer who have failed first-generation epidermal growth factor receptor-tyrosine kinase inhibitors ...
Yi-Tian Qi MM, Yi Hou PhD, Liang-Chen Qi MD   +2 more
doaj   +1 more source

Dynamic tracing for epidermal growth factor receptor mutations in urinary circulating DNA in gastric cancer patients

Tumor Biology, 2017
The mutations of epidermal growth factor receptor are detected in gastric cancer, indicating its suitability as a target for receptor tyrosine kinase inhibitors, as well as a marker for clinical outcome of chemotherapeutic treatments. However, extraction
Xiu-Qin Shi, Wen-Hua Xue, Song-Feng Zhao, Xiao-Jian Zhang, Wukong Sun   +4 more
doaj   +1 more source

miRNA-9 Inhibits Proliferation and Migration of Lung Squamous Cell Carcinoma Cells by Regulating NRSF/EGFR

Technology in Cancer Research & Treatment, 2020
Background: To investigate the mechanism of microRNA9 in inhibiting proliferation and migration of lung squamous cell carcinoma cells via neuron-restricted silencing factor/epidermal growth factor receptor.
Kangning Wang MD, Kai Xu MM, Xuefeng Leng MD, Yongtao Han BM, Qiang Fang MD   +4 more
doaj   +1 more source

EFEMP1 binds the EGF receptor and activates MAPK and Akt pathways in pancreatic carcinoma cells [PDF]

, 2009
The EGF-related protein EFEMP1 (EGF-containing fibulin-like extracellular matrix protein 1) has been shown to promote tumor growth in human adenocarcinoma.
Jauch, Karl-Walter, Krebs, Stefan, Blum, Helmut, Bruns, Christiane J., De Toni, Enrico N., Ischenko, Ivan, Camaj, Peter, Seeliger, Hendrik, Faktorova, Dagmar   +8 more
core   +1 more source

Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients

Clinics, 2012
OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics.
Carlos E. Bacchi, Heloísa Ciol, Eduardo M. Queiroga, Lucimara C. Benine, Luciana H. Silva, Elida B. Ojopi   +5 more
doaj   +1 more source

A case of epidermal growth factor receptor tyrosine kinase inhibitor effectiveness in epidermal growth factor receptor mutation-positive squamous cell carcinoma

SAGE Open Medical Case Reports, 2023
A 71-year-old non-smoker woman was admitted to our hospital because of left front chest pain. A computed tomography scan showed a large mass of >7.0 cm in the lower left part of the lung and multiple organ metastases in the liver, brain, bone, and left ...
Sosuke Matsumura, Satoshi Ano, Norihiro Kikuchi, Michiko Masuda, Hajime Osawa, Yuzuru Kondo, Yukio Ishii, Nobuyuki Hizawa   +7 more
doaj   +1 more source

Frequent Epidermal Growth Factor Receptor Gene Mutations in Malignant Pleural Effusion of Lung Adenocarcinoma

, 2011
Malignant pleural effusions (MPEs) are often observed in lung cancer, especially adenocarcinoma. Epidermal growth factor receptor (EGFR) gene mutations are usually detected in lung adenocarcinoma.
吳尚俊;高劍虹;余忠仁;張逸良;楊志新;施金元;李元麒;楊泮池, WU, SHANG-GIN;GOW, CHIEN-HUNG;YU, CHONG-JEN;CHANG, YIH-LEONG;YANG, CHIH-HSIN;SHIH, JIN-YUAN;LEE, YUNG-CHIE;YANG, PAN-CHYR   +1 more
core   +1 more source

The effect of distant metastases sites on survival in de novo stage-IV breast cancer: A SEER database analysis

Tumor Biology, 2017
To investigate the effect of distant metastases sites on survival in patients with de novo stage-IV breast cancer. From 2010 to 2013, patients with a diagnosis of de novo stage-IV breast cancer were identified using the Surveillance, Epidemiology, and ...
San-Gang Wu, Hui Li, Li-Ying Tang, Jia-Yuan Sun, Wen-Wen Zhang, Feng-Yan Li, Yong-Xiong Chen, Zhen-Yu He   +7 more
doaj   +1 more source

Single-domain antibodies for radio nuclear imaging and therapy of esophageal squamous cell carcinoma: a narrative review

Journal of Bio-X Research, 2020
. Single-domain antibodies have the characteristics of small molecular weight, strong tissue penetration, and high affinity, and are widely used to construct molecular probes for disease diagnosis and treatment.
Huifang Liu, Xu Nie, Zhenchao Tian, Dan Chen, Xueli Chen, Qi Zeng, Xinyi Xu   +6 more
doaj   +1 more source