Results 141 to 150 of about 29,755 (230)

E3 Ubiquitin Ligases in MASH‐Associated Liver Fibrosis: Mechanisms and Therapeutic Opportunities

open access: yesLiver International, Volume 46, Issue 10, October 2026.
ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a major cause of progressive liver fibrosis and can ultimately lead to cirrhosis and hepatocellular carcinoma (HCC). MASH‐associated liver fibrosis develops through a complex interplay among lipotoxic hepatocyte injury, oxidative and endoplasmic reticulum stress, inflammatory ...
Ah‐Reum Oh   +8 more
wiley   +1 more source

A novel CsRNF‐CsHSF24‐CsF3′5′H2 module regulates epigallocatechin gallate biosynthesis in Camellia sinensis

open access: yesThe Plant Journal, Volume 128, Issue 1, October 2026.
Significance Statement While the biosynthetic pathway of tea catechins is well established, how post‐translational modifications govern this process has remained elusive. This study uncovers a regulatory module in which the E3 ubiquitin ligase CsRNF targets the transcription factor CsHSF24 for degradation, thereby controlling expression of the key ...
Xinzhuan Yao   +9 more
wiley   +1 more source

Safety of frozen paste from blanched, whole migratory locust (Locusta migratoria) as a novel food pursuant to Regulation (EU) 2015/2283

open access: yesEFSA Journal, Volume 24, Issue 10, October 2026.
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen paste from blanched, whole migratory locusts (Locusta migratoria) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is produced from farmed sub‐adult L. migratoria, which
EFSA Panel on Nutrition   +23 more
wiley   +1 more source

Multimodal Transformer Fusion of PTR‐ToF‐MS Volatiles and Targeted Non‐Volatile Metabolites Enables Data‐Driven Grading of Baimudan White Tea

open access: yesRapid Communications in Mass Spectrometry, Volume 40, Issue 18, 30 September 2026.
ABSTRACT Rationale Commercial grading of Baimudan white tea still relies largely on sensory evaluation and would benefit from a rapid, objective analytical approach. This study investigated whether PTR‐ToF‐MS volatile fingerprints combined with targeted non‐volatile metabolite measurements could support data‐driven grading of four official Baimudan ...
Dandan Zhang   +2 more
wiley   +1 more source

Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin. [PDF]

open access: yesJ Biol Chem
Amin ARMR   +9 more
europepmc   +1 more source

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