E3 Ubiquitin Ligases in MASH‐Associated Liver Fibrosis: Mechanisms and Therapeutic Opportunities
ABSTRACT Metabolic dysfunction‐associated steatohepatitis (MASH) is a major cause of progressive liver fibrosis and can ultimately lead to cirrhosis and hepatocellular carcinoma (HCC). MASH‐associated liver fibrosis develops through a complex interplay among lipotoxic hepatocyte injury, oxidative and endoplasmic reticulum stress, inflammatory ...
Ah‐Reum Oh +8 more
wiley +1 more source
Effect of Epigallocatechin-3-Gallate on Depression-Related Cytokines in Thalassemia Patients: Molecular and Cellular Evaluation. [PDF]
Salman MN +5 more
europepmc +1 more source
Significance Statement While the biosynthetic pathway of tea catechins is well established, how post‐translational modifications govern this process has remained elusive. This study uncovers a regulatory module in which the E3 ubiquitin ligase CsRNF targets the transcription factor CsHSF24 for degradation, thereby controlling expression of the key ...
Xinzhuan Yao +9 more
wiley +1 more source
Study on the Role of FGF9/ERK/MMP9 Pathway in Age-Related Cataract and in (-)-Epigallocatechin-3-gallate Protecting Lens Epithelial Cells From Apoptosis. [PDF]
Yu J +12 more
europepmc +1 more source
Abstract Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on frozen paste from blanched, whole migratory locusts (Locusta migratoria) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is produced from farmed sub‐adult L. migratoria, which
EFSA Panel on Nutrition +23 more
wiley +1 more source
Effect of Melatonin and Epigallocatechin-3-Gallate Combination on In Vitro Maturation of Mouse Oocytes. [PDF]
Li S, Chen L, Li Y, Xu L, Chen Y, Ma Y.
europepmc +1 more source
ABSTRACT Rationale Commercial grading of Baimudan white tea still relies largely on sensory evaluation and would benefit from a rapid, objective analytical approach. This study investigated whether PTR‐ToF‐MS volatile fingerprints combined with targeted non‐volatile metabolite measurements could support data‐driven grading of four official Baimudan ...
Dandan Zhang +2 more
wiley +1 more source
Epigallocatechin-3-gallate suppressed breast oncogenesis via the miR-27a/Wnt/β-catenin pathway axis. [PDF]
Banerjee S, Mandal AKA.
europepmc +1 more source
Epigallocatechin-3-Gallate Suppresses Glioma by Targeting Integrin αvβ3/FAK/ERK Signaling Axis and Matrix Metalloproteinases. [PDF]
Sun R +7 more
europepmc +1 more source
Enhanced anti-tumor activity by the combination of the natural compounds (-)-epigallocatechin-3-gallate and luteolin. [PDF]
Amin ARMR +9 more
europepmc +1 more source

