Results 131 to 140 of about 13,289,951 (302)

Epigallocatechin Gallate (Egcg) Suppresses Beta-Amyloid-Induced Neurotoxicity through Inhibiting C-Abl/Fe65 Nuclear Translocation and Gsk3 Beta Activation

open access: yes, 2011
Alzheimer's disease (AD) is the most common neurodegenerative disease and is caused by an accumulation of A beta plaque deposits in the brains. Evidence is increasing that green can flavonoids can protect cells from A beta-mediated neurotoxicity. However,
林志立;陳達夫;邱銘章;魏宗德;林仁混   +1 more
core  

Natural Products as Modulators of ABC Transporters in Breast Cancer

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan   +2 more
wiley   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang   +7 more
wiley   +1 more source

Flavonoids in Nasal Therapeutics: Biological Activities, Delivery Challenges, and Formulation Strategies–A Systematic Review

open access: yesPhytotherapy Research, EarlyView.
Overview of the therapeutic potential of flavonoids in nasal delivery systems, highlighting their benefits to the human nasal cavity, and applications in the treatment of respiratory and brain‐related diseases. ABSTRACT Flavonoids represent a significant group of secondary metabolites.
Jeniffer Viviana Ramirez Hernández   +5 more
wiley   +1 more source

Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT Cancer remains a leading cause of global mortality, with the therapeutic efficacy of anticancer drugs often hampered by late diagnosis and the development of chemotherapy resistance. Ferroptosis is an iron‐dependent form of regulated non‐apoptotic cell death driven by lipid peroxidation.
Valentina Citi   +6 more
wiley   +1 more source

Epigallocatechin-3-gallate location and interaction with late endosomal and plasma membrane model membranes by molecular dynamics

open access: yes, 2018
Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea and it has been reported to have many beneficial properties against many different types of illnesses and infections.
José Villalaín (374758)
core   +1 more source

A general and green approach of pH‐sensitive ZIF‐67 for encapsulating active substances

open access: yesSmart Molecules, EarlyView.
Zeolitic imidazolate framework‐67 (ZIF‐67) was successfully synthesized in deionized water for 2 h in this work; meanwhile, various active substances could be encapsulated in one‐pot with the same process, resulting in high loading rates. The study delved into the growth mechanism, morphological difference and loading capacity.
Xinyi Sun   +6 more
wiley   +1 more source

Epigallocatechin-3-gallate enhances the osteoblastogenic differentiation of human adipose-derived stem cells

open access: yes, 2019
Jing Zhang,1 Kai Wu,2 Ting Xu,3 Jiajun Wu,1 Pengfei Li,1 Hong Wang,4 Huiling Wu,1 Gang Wu5 1Department of Plastic and Aesthetic Center, The First Affiliated Hospital of Zhejiang University, Hangzhou, Zhejiang, China; 2Spine Lab, Department of Orthopedic
Wu K   +7 more
core  

(-)-Epigallocatechin-3-gallate encapsulated realgar nanoparticles exhibit enhanced anticancer therapeutic efficacy against acute promyelocytic leukemia

open access: yes, 2019
Realgar and (-)-Epigallocatechin-3-gallate (EGCG) are natural medicines that inhibit cancer cell growth, resulting in inhibition of formation and development of tumors.
Wei Fang (116739)   +5 more
core   +1 more source

Cuproptosis Inducers in Cancer Therapy: State of the Art and Challenges

open access: yesThe Chemical Record, EarlyView.
Cuproptosis is emerging as a distinct copper‐dependent cell death pathway, highlighting copper as a potential metabolic vulnerability in cancer. This review examines how coordination chemistry, redox regulation, and nanomaterial design shape Cu reactivity and therapeutic outcomes.
Chiara Ragusa, Valentina Oliveri
wiley   +1 more source

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