Results 191 to 200 of about 29,755 (230)

Epigallocatechin-3-Gallate, a Promising Molecule for Parkinson's Disease?

Rejuvenation Research, 2015
Parkinson's disease (PD) is the second most common neurodegenerative disease, and it is characterized by the loss of the neurotransmitter dopamine and neuronal degeneration in the substantia nigra pars compacta. Thus far, current therapeutic strategies have failed to address neuronal degeneration.
Renaud Justine, Nabavi Seyed Fazel, Daglia Maria, Nabavi Seyed Mohammad, Martinoli Maria-Grazia   +4 more
openaire   +4 more sources

Chemoprevention of fibroid tumors by [−]-epigallocatechin-3-gallate in quail

Nutrition Research, 2008
Spontaneous leiomyomas of the oviduct are common tumors of the Japanese quail (Coturnix coturnix japonica), and fibroid tumors in the laying hen are similar to human fibroid tumors with respect to estrogen and progesterone receptors. This makes the quail a good animal model for screening potential agents for that aid in the prevention and treatment of ...
Ibrahim H, Ozercan, Nurhan, Sahin, Fatih, Akdemir, Muhittin, Onderci, Soley, Seren, Kazim, Sahin, Omer, Kucuk   +6 more
openaire   +2 more sources

The effects of epigallocatechin-3-gallate on extracellular matrix metabolism

Journal of Dermatological Science, 2005
Anti-oxidants have attracted a lot of interest on account of their function to protect the skin from oxidative stress by ultraviolet (UV) radiation.This study examined the effects of epigallocatechin-3-gallate (EGCG), which is a green tea extract, on the extracellular matrix (ECM) changes induced by UV radiation and showed the comparative results with ...
Jong Hee, Lee, Jin Ho, Chung, Kwang Hyun, Cho   +2 more
openaire   +2 more sources

Inhibition of influenza virus internalization by (−)-epigallocatechin-3-gallate

Antiviral Research, 2013
(-)-Epigallocatechin-3-gallate (EGCG), one of the major flavonoid components of green tea, is known to have a broad antiviral activity against several enveloped viruses, including the influenza virus. However, its mode of action and the mechanism that allows it to target influenza virus molecules have not been fully elucidated.
Meehyein, Kim, So-Yeon, Kim, Hye Won, Lee, Jin Soo, Shin, Pilho, Kim, Young-Sik, Jung, Hyeong-Seop, Jeong, Jae-Kyung, Hyun, Chong-Kyo, Lee   +8 more
openaire   +2 more sources

Effect Of epigallocatechin-3-gallate on the pharmacokinetics of amlodipine in rats

Xenobiotica, 2018
This study investigates the effect of epigallocatechin-3-gallate (EGCG), a major ingredient of green tea, on the pharmacokinetics of amlodipine in rats. The pharmacokinetics of orally administered amlodipine (1 mg/kg) with or without EGCG pretreatment (30 mg/kg/day for 10 days) were investigated.
Xiuyuan, Han, Haixia, Zhang, Huihui, Hao, Hangao, Li, Xichun, Guo, Dong, Zhang   +5 more
openaire   +2 more sources

Epigallocatechin-3-gallate(EGCG): Mechanisms and the Combined Applications

Combinatorial Chemistry & High Throughput Screening, 2018
EGCG is the most important pharmacological component in tea. Researches have confirmed its effects, including anti-tumor, anti-inflammation, anti-aging, anti-obesity, anti-diabetic, cardiovascular disease prevention and protection, immunoregulation and neuroprotection. Paradoxically, the clinical application of EGCG is very rare.
Xuekun, Song, Juan, Du, Wenyuan, Zhao, Zheng, Guo   +3 more
openaire   +2 more sources

(−)-Epigallocatechin-3-gallate Inhibits Fibrillogenesis of Chicken Cystatin

Journal of Agricultural and Food Chemistry, 2015
Previous studies have reported that (-)-epigallocatechin-3-gallate (EGCG), the most abundant flavonoid in green tea, can bind to unfolded native polypeptides and prevent conversion to amyloid fibrils. To elucidate whether this antifibril activity is specific to disease-related target proteins or is more generic, we investigated the ability of EGCG to ...
Na, Wang, Jianwei, He, Alan K, Chang, Yu, Wang, Linan, Xu, Xiaoying, Chong, Xian, Lu, Yonghui, Sun, Xichun, Xia, Hui, Li, Bing, Zhang, Youtao, Song, Akio, Kato, Gary W, Jones   +13 more
openaire   +2 more sources

Microneedle‐mediated intradermal delivery of epigallocatechin‐3‐gallate

International Journal of Cosmetic Science, 2016
AbstractObjectiveEpigallocatechin‐3‐gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50–80% of green tea catechins. It is an anti‐inflammatory, antioxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular ...
A, Puri, H X, Nguyen, A K, Banga
openaire   +2 more sources

Chemoprevention by Epigallocatechin-3-Gallate (EGCG)

2017
Tea that is obtained from leaves of the plant Camellia sinensis is subsequent to water and is the most extensively consumed drink in the world. Black, green, and oolong tea are the forms which are produced by the different processing and manufacturing techniques making them chemically different from each other resulting for around 75 %, 23 %, and 2 ...
openaire   +1 more source

Analysis of the Antimicrobial Activity of Epigallocatechin-3-Gallate (EGCG)

Bulletin of Experimental Biology and Medicine
We studied antimicrobial activity of epigallocatechin-3-gallate (EGCG), a green tea polyphenolic catechin, and its combined use with ceftazidime (CAZ) against bacterial strains of Klebsiella pneumoniae. EGCG exhibited no activity against strains of K. pneumoniae with a different sensitivity to CAZ.
V V, Muravieva, B O, Bembeeva, T V, Priputnevich, V I, Kiselev   +3 more
openaire   +2 more sources