Results 201 to 210 of about 13,289,951 (302)

The Radioprotective Effects of (-)-Epigallocatechin-3-gallate (EGCG): Restoring the Gut Microbiota-Immune Axis to Ameliorate Radiation-Induced Intestinal Injury. [PDF]

Dose Response
Gu J, Guo Q, Hua Q, Tang Z, Yang Y, Ji C, Yu J, Zhu D, Feng Q, Xu J, Zhao L.   +10 more
europepmc   +1 more source

Edible Fungus Compound Cordycepin Protects Against Acetaminophen‐Induced Liver Injury

Journal of Clinical Laboratory Analysis, Volume 40, Issue 11, June 2026.
This study demonstrates that pretreatment with cordycepin (COR) effectively protects against acetaminophen (APAP)‐induced acute liver injury in mice. COR mitigates liver damage by exerting strong antioxidant, anti‐inflammatory, and anti‐apoptotic effects through the modulation of ER proteostasis, HIF‐1, and PPAR signaling networks.
Chunjin Fu, Shuyu Li, Shengnan Shen, Chengchao Xu, Jingjing Liao, Na Lin   +5 more
wiley   +1 more source

Dual‐Responsive Chitosan‐Grafted PNIPAAm Hydrogel Eye Drop Incorporating Insulin‐Imprinted Microgels for Dry Eye Syndrome Treatment

Macromolecular Bioscience, Volume 26, Issue 6, June 2026.
ABSTRACT Dry eye syndrome (DES) happens as a result of inadequate tear secretion or excessive evaporation, which leads to ocular surface irritation and damage. A major therapeutic challenge is maintaining effective drug concentrations, as topical formulations are rapidly cleared by blinking and tear turnover.
Masoumeh Alsadat Hosseini, Reihaneh Khademi, Mahshid Shokri, Reza Ghiasi, Ali Doostmohammadi, Mahshid Kharaziha, Sahar Salehi   +6 more
wiley   +1 more source

Epigallocatechin-3-gallate ameliorates lipopolysaccharide-induced inflammation via the 67LR/JAK2/STAT3 signaling pathway. [PDF]

Sci Rep
Fan S, Fan X, Ma N, Yin G, Zhang C, Liang Y, Luo Y, Deng Y, Zuo J, Tang J, Luo D, Fan X.   +11 more
europepmc   +1 more source

Exploring and Targeting the Connection of Iron and Copper Homeostasis to Neurodegenerative Diseases

MedComm, Volume 7, Issue 6, June 2026.
Iron and copper dyshomeostasis, along with their interactions with key intrinsically disordered proteins (e.g., Aβ, tau, α‐synuclein) have a strong implication in the onset and progression of neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), Prion diseases (PrDs), Huntington's disease (HD), Wilson's disease (WD),
Xin Liu, Lin Jia, Kerong Wu, Mo Chen, Jichao Sun, Chuanbin Yang, Chengchao Xu, Jie Sun, Jigang Wang, Lingyun Dai   +9 more
wiley   +1 more source

Therapeutic potential of green tea's epigallocatechin-3-gallate in oral cancer: a comprehensive systematic review of cellular and molecular pathways. [PDF]

Discov Oncol
Ramsridhar S, Veeraraghavan VP, Adtani PN, Francis AP, Rajkumar C, Balasubramanian M, Kalaivanan D.   +6 more
europepmc   +1 more source

Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 6, June 2026.
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang, Chenyang Mu, Rui Zhao, Runwei Ma, Xuehai Liu, Haoling Zhang, Zengwu Wang, Jing‐jing Zhang   +7 more
wiley   +1 more source

Multitarget Mechanisms of (‒)‒Epigallocatechin-3-Gallate Against MRSA: From SraP L-Lectin Targeting to Synergistic Antibiotic Effects. [PDF]

Pathogens
Zheng P, Zhang P, Li Y, Long J, Liu F, Yang H.   +5 more
europepmc   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

Epigallocatechin-3-gallate conjugated with selenium nanoparticles prevents neurological complications in rats exhibiting schizophrenia-like behaviors. [PDF]

Front Pharmacol
Gamal El-Deen HM, Essawy AE, Mohammed NA, Abdelfattah MS, Fathalla AS, El-Khadragy MF, Abdel Moniem AE.   +6 more
europepmc   +1 more source