Results 41 to 50 of about 45,935 (222)

Versatile Microgel Platform for Intervertebral Disc Degeneration Therapy: Targeting Pericyte‐Mediated Fibrosis and Protecting Nucleus Pulposus Cells

Advanced Science, EarlyView.
The engineered MMS@TRP microgel enables targeted, acid‐responsive delivery of a miR‐21 inhibitor to pericytes. It effectively suppresses disc fibrosis by inhibiting TGF‐β signaling while protecting nucleus pulposus cells via sustained, antioxidant tannic acid release.
Fei Ma, Zhen Zhao, Chuan Guo, Yuheng Liu, Yu Wang, Dengbo Yao, Weiqiang Lan, Dejun Zhong, Chen Fan, Yao He, Mei Zhang, Qingquan Kong, Yunfeng Lin   +12 more
wiley   +1 more source

Impact of Acute Phase Epigallocatechin-3-gallate Supplementation on Consciousness and S100B Serum Levels in TBI Patients: A Double Blind Randomized Clinical Trial

Iranian Journal of Neurosurgery, 2017
Background and Aim: Traumatic brain injury is one of the leading causes of mortality and disability in young adults. Epigallocatechin-3-gallate, the antioxidant compound of green tea, has been proposed to have antioxidant and anti-inflammatory properties.
Leila Zareian, Amir Azarhomayoun, Maysam Alimohamadi, Mohammadreza Khajavi, Soodeh Razeghi-Jahromi   +4 more
doaj  

Evaluation of In Vitro Antimicrobial Activity of Epigallocatechin Gallate (EGCG) and Green Tea (Camellia Sinensis) Oil on Various Pathogens

Genel Tıp Dergisi
Aim: EGCG, the polyphenolic component of Camellia sinesis catechins, and Camellia sinesis extract have broad antimicrobial activity. To investigate the invitro antibacterial and antifungal activity of the Epigallocatechin gallate and Camellia sinesis ...
Hale Köksoy, Cennet Ragbetli
doaj   +1 more source

FORMULATION AND CHARACTERIZATION OF EPIGALLOCATECHIN GALLATE NANOPARTICLES

, 2015
FORMULATION AND CHARACTERIZATION OF EPIGALLOCATECHIN GALLATE NANOPARTICLES   EGCG have variety of therapeutic advantages including HIV. Check wikipedia "https://en.wikipedia.org/wiki/Epigallocatechin_gallate"   Cite: Ramkumar Ponnuraj et al.
Ramkumar Ponnuraj (687401)
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

Animal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu, Aosi Qi, Shuyu Zhong, Haozhen Du, Shimeng Guo, Hongsheng Ouyang, Hongming Yuan, Daxin Pang, Zicong Xie   +8 more
wiley   +1 more source

Synthesis and Biological Testing of Novel Glucosylated Epigallocatechin Gallate (EGCG) Derivatives

Molecules, 2016
Epigallocatechin gallate (EGCG) is the most abundant component of green tea catechins and has strong physiological activities. In this study, two novel EGCG glycosides (EGCG-G1 and EGCG-G2) were chemoselectively synthesized by a chemical modification ...
Xin Zhang, Jing Wang, Jiang-Miao Hu, Ye-Wei Huang, Xiao-Yun Wu, Cheng-Ting Zi, Xuan-Jun Wang, Jun Sheng   +7 more
doaj   +1 more source

Epigallocatechin-3-gallate (EGCG) inhibits the migratory behavior of tumor bronchial epithelial cells-0

, 2011
Orescent probe propidium iodide was used to visualize dead cells. Compared to control (A) or to 5 μg/ml (B) and 10 μg/ml (C) of EGCG, we observed that 20 μg/ml (D) of EGCG induced a significant (p < 0.01) increase in the dead cell number (E).Copyright ...
Myriam Polette (58028), Magali Milliot (58025), Christine Terryn (58026), Philippe Birembaut (58029), Jérôme Cutrona (58027), Salma Hazgui (58022), Jean-Marie Zahm (27105), Arnaud Bonnomet (58023), Béatrice Nawrocki-Raby (58024)   +8 more
core   +1 more source

l‑Theanine Inhibits (−)-Epigallocatechin-3-gallate Oxidation via Chelating Copper

, 2022
Our recent study showed that glutamate can inhibit dopamine oxidation via chelating copper. l-Theanine is an amino acid analogue of glutamate, whereas tea (−)-epigallocatechin-3-gallate (EGCG) is similar to dopamine in avidly undergoing oxidation.
Xiaoxiao Wang (337498), Xiuli Li (133764), Lijie Jia (12867862), Fuming Wang (563976), Jinsong Zhang (42064), Dongxu Wang (2562808), Ke Zhang (115386)   +6 more
core   +1 more source

Valorization of bark extracts from Cerrado and Amazon species: phenolic characterization, antioxidant capacity, and photoprotective potential for circular bioeconomy applications

Biofuels, Bioproducts and Biorefining, EarlyView.
Abstract Tree bark remains an underexploited source of high‐value‐added phenolic compounds with potential circular bioeconomy applications. This work characterized bark extracts from two species of distinct Brazilian biomes, Stryphnodendron adstringens (Cerrado) and Myrcia eximia (Amazon), obtained with three solvents (ethanol, methanol and acetone ...
Mário Sérgio Lorenço, Danilo José Machado de Abreu, Elesandra da Silva Araujo, Uasmim Lira Zidanes, Laise de Jesus dos Santos, Denisse Concepción Vega Villarruel, Elisângela Elena Nunes Carvalho, Fábio Akira Mori   +7 more
wiley   +1 more source

Comparative study of anti-inflammatory, antioxidant and antibacterial activities of epigallocatechin gallate, epigallocatechin, epicatechin gallate and epicatechin in vitro

Pharmacological Research - Modern Chinese Medicine
Introduction: catechin compounds are flavanols substance from various natural plants, and play a significant part in anti-inflammatory, anti-tumor, anti-oxidation, anti-bacteria and protecting the heart and brain organs and other pharmacological effects,
Shuqi Wang, Yu Chang, Jingji Xu, Chenru Zhao, Yang Song, Mingchun Liu, Chunlian Tian   +6 more
doaj   +1 more source