Results 21 to 30 of about 20,159 (200)

Theanine Improves High-Dose Epigallocatechin-3-Gallate-Induced Lifespan Reduction in Caenorhabditis elegans

Foods, 2021
Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea. Our previous report showed that induced hormesis was a critical determinant for the promotion of a healthy lifespan in Caenorhabditis elegans.
Yuxuan Peng, Shen Dai, Yan Lu, Ligui Xiong, Jianan Huang, Zhonghua Liu, Yushun Gong   +6 more
doaj   +1 more source

Protective Effects of Epigallocatechin Gallate (EGCG) on Endometrial, Breast, and Ovarian Cancers. [PDF]

Biomolecules, 2020
Green tea and its major bioactive component, (−)-epigallocatechin gallate (EGCG), possess diverse biological properties, particularly antiproliferation, antimetastasis, and apoptosis induction. Many studies have widely investigated the anticancer and synergistic effects of EGCG due to the side effects of conventional cytotoxic agents.
Huang YJ, Wang KL, Chen HY, Chiang YF, Hsia SM.   +4 more
europepmc   +5 more sources

Epigallocatechin 3-gallate inhibits the plasma membrane Ca2+-ATPase: effects on calcium homeostasis

Heliyon, 2021
Flavonoids are natural compounds responsible for the health benefits of green tea. Some of the flavonoids present in green tea are catechins, among which are: epigallocatechin, epicatechin-3-gallate, epicatechin, catechin and epigallocatechin-3-gallate ...
Débora E. Rinaldi, Mallku Q. Ontiveros, Nicolas A. Saffioti, Maximiliano A. Vigil, Irene C. Mangialavori, Rolando C. Rossi, Juan P. Rossi, María V. Espelt, Mariela S. Ferreira-Gomes   +8 more
doaj   +1 more source

The epigallocatechin gallate derivative Y6 reverses drug resistance mediated by the ABCB1 transporter both in vitro and in vivo

Acta Pharmaceutica Sinica B, 2019
Previously, we reported that Y6, a new epigallocatechin gallate derivative, is efficacious in reversing doxorubicin (DOX)--mediated resistance in hepatocellular carcinoma BEL-7404/DOX cells.
Yan Wen, Ruiqiang Zhao, Pranav Gupta, Yingfang Fan, Yunkai Zhang, Zhenguang Huang, Xiaohui Li, Yuangang Su, Lijuan Liao, Yu-An Xie, Donghua Yang, Zhe-Sheng Chen, Gang Liang   +12 more
doaj   +1 more source

Neuroprotective Effects of Quercetin and Rutin on Spatial Memory Impairment in an 8-Arm Radial Maze Task and Neuronal Death Induced by Repeated Cerebral Ischemia in Rats

Journal of Pharmacological Sciences, 2007
In order to determine the differential effects of flavonoids on cerebral ischemia, we investigated the effects of (−)-epigallocatechin gallate (EGCG), catechin, rutin, and quercetin on spatial memory impairment and neuronal death induced by repeated ...
Fengling Pu, Kenichi Mishima, Keiichi Irie, Kyouko Motohashi, Yurika Tanaka, Kensuke Orito, Takashi Egawa, Yoshihisa Kitamura, Nobuaki Egashira, Katsunori Iwasaki, Michihiro Fujiwara   +10 more
doaj   +1 more source

Epigallocatechin gallate, the primary bioactive component from Camellia sinensis: A review on immunomodulatory effects in autoimmune diseases by balancing the differentiation of Th and Treg cells [PDF]

Journal of HerbMed Pharmacology
Autoimmune disease is a chronic condition that requires treatment with prolonged use of drugs. Consequently, there is a significant occurrence of adverse effects and toxicity associated with the medicine. On the other hand, epigallocatechin gallate (EGCG)
Vigha Ilmanafi Arifka, Andayana Puspitasari Gani, Retno Murwanti   +2 more
doaj   +1 more source

Protective Effect of Liposomal Epigallocatechin-Gallate in Experimental Gentamicin-Induced Hepatotoxicity

Antioxidants, 2022
Our study aimed to assess the effect of liposomal epigallocatechin-gallate (LEGCG) compared with epigallocatechin-gallate (EGCG) solution on hepatic toxicity induced by gentamicin (G) administration in rats.
Adriana Elena Bulboacă, Alina Silvia Porfire, Vasile Rus, Cristina Ariadna Nicula, Corneliu Angelo Bulboacă, Sorana D. Bolboacă   +5 more
doaj   +1 more source

Inhibition of FLT3 expression by green tea catechins in FLT3 mutated-AML cells. [PDF]

PLoS ONE, 2013
Acute myeloid leukemia (AML) is a heterogeneous disease characterized by a block in differentiation and uncontrolled proliferation. FLT3 is a commonly mutated gene found in AML patients.
Bui Thi Kim Ly, Hoang Thanh Chi, Makoto Yamagishi, Yasuhiko Kano, Yukihiko Hara, Kazumi Nakano, Yuko Sato, Toshiki Watanabe   +7 more
doaj   +1 more source

Enhancement of Annexin V in response to combination of epigallocatechin gallate and quercetin as a potent arrest the cell cycle of colorectal cancer

Brazilian Journal of Biology, 2021
Colorectal cancer (CRC) is one of the most common cancers leading to comorbidities and mortalities globally. The rational of current study was to evaluate the combined epigallocatechin gallate and quercetin as a potent antitumor agent as commentary agent
Maryam A. Al-Ghamdi, A. AL-Enazy, E.A Huwait, A. Albukhari, S. Harakeh, Said S. Moselhy   +5 more
doaj   +1 more source

(-)-Epigallocatechin-3-gallate Reduces Cigarette Smoke-Induced Airway Neutrophilic Inflammation and Mucin Hypersecretion in Rats

Frontiers in Pharmacology, 2017
Background: Cigarette smoking is the leading cause of chronic obstructive pulmonary disease. (-)-Epigallocatechin-3-gallate (EGCG), the major catechins in Chinese green tea, has been studied for its anti-oxidative and anti-inflammatory properties in cell
Yingmin Liang, Yingmin Liang, Yingmin Liang, Kenneth W. K. Liu, Kenneth W. K. Liu, Sze C. Yeung, Sze C. Yeung, Xiang Li, Xiang Li, Mary S. M. Ip, Mary S. M. Ip, Mary S. M. Ip, Judith C. W. Mak, Judith C. W. Mak, Judith C. W. Mak, Judith C. W. Mak   +15 more
doaj   +1 more source