Results 51 to 60 of about 2,699,284 (182)
Recent Developments and Evolving Therapeutic Strategies in KMT2A‐Rearranged Acute Leukemia
ABSTRACT Background Rearrangements of the histone‐lysine‐N‐methyltransferase (KMT2A), previously referred to as mixed‐lineage leukemia (MLL), are among the most common chromosomal abnormalities in patients with acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL), involving numerous different fusion partners.
Lei Yin +4 more
wiley +1 more source
Reminiscences on the honeybee genome project and the rise of epigenetic concepts in insect science
The honeybee genome project was an important milestone in social insect research that opened new possibilities for the community's quest to study social evolution at molecular and cellular levels. Among new lines of research, the epigenomic modifications to DNA, histones and RNAs gained special prominence as potential drivers of phenotypic and ...
Ryszard Maleszka
wiley +1 more source
Epigenesis of Pure Reason and the Source of Pure Cognitions [PDF]
Kant describes logic as “the science that exhaustively presents and strictly proves nothing but the formal rules of all thinking”. (Bviii-ix) But what is the source of our cognition of such rules (“logical cognition” for short)?
Lu-Adler, Huaping
core
Introduction to the Special Issue on Complex Networks, Artificial Life journal.Comment: 7 pages, in ...
Gershenson, Carlos, Prokopenko, Mikhail
core +1 more source
Boolean network model predicts cell cycle sequence of fission yeast [PDF]
A Boolean network model of the cell-cycle regulatory network of fission yeast (Schizosaccharomyces Pombe) is constructed solely on the basis of the known biochemical interaction topology.
A Faure +40 more
core +5 more sources
Epigenetic associations of GPNMB rs199347 variant with alcohol consumption in Parkinson’s disease
IntroductionAlcohol consumption can induce a neuroinflammatory response and contribute to the progression of neurodegeneration. However, its association with Parkinson’s disease (PD), the second most common neurodegenerative disorder, remains ...
Yen-Chung Chen +10 more
doaj +1 more source
Genetic, epigenetic and exogenetic information [PDF]
We describe an approach to measuring biological information where ‘information’ is understood in the sense found in Francis Crick’s foundational contributions to molecular biology.
Griffiths, Paul Edmund, Stotz, Karola
core
Man and embryo: Historicizing ideas about humanity in the study of reproduction, 18th–19th centuries
Abstract This article is concerned with historicizing the idea that all people belong to a single collective of biological human beings. It analyzes implications and changes in the concept of “Man” over the 18th and 19th centuries, particularly in the study of reproduction and embryos.
Chiara Lacroix
wiley +1 more source
Tastes of the Parents: epigenetics and its role in evolutionary aesthetics [PDF]
Evolutionary Aesthetics is a bourgeoning and thriving sub-field of Aesthetics, the main aim of which is “the importation of aesthetics into natural sciences, and especially its integration into the heuristic of Darwin’s evolutionary theory.” Scholars ...
MANDRIOLI, Mauro, Portera, M.
core
Inferring Biologically Relevant Models: Nested Canalyzing Functions [PDF]
Inferring dynamic biochemical networks is one of the main challenges in systems biology. Given experimental data, the objective is to identify the rules of interaction among the different entities of the network.
Hinkelmann, Franziska +1 more
core +3 more sources

