Results 31 to 40 of about 31,778 (128)

Relationship between the expression level of microRNA and the features of clinical course of the gallbladder and Оddi's sphincter functional disorders in children

Zaporožskij Medicinskij Žurnal, 2019
The aim of the work is to establish the relationship between the expression levels of microRNA-378f, microRNA-4311, microRNA-4714-3p and anamnestic, clinical and paraclinical parameters of functional disorders of the gallbladder and Oddi's sphincter (FD ...
O. Ye. Abaturov, V. L. Babуch
doaj   +1 more source

Factors and mechanisms of productive secondary reservoirs formation in deep-lying oil and gas complexes. Article 1. Tectonophysical mechanisms of Lower Carboniferous quartzite-sandstones decompaction in the central part of the Dniprovsko-Donetska depression at the depths of more than 4.5 km

Мінеральні ресурси України
In the world, the scale of development of secondary reservoirs in decompaction rock bodies in a wide formation range is steadily increasing: from the crystalline basement of different ages of various oil and gas-bearing basins to terrigenous deposits ...
O. Yu. Lukin, I. P. Gafych, Ya. V. Lukin
doaj   +1 more source

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 270-290, June 2026.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green, Laura Horsfall, Azam Saied   +2 more
wiley   +1 more source

Interplay between the HPA axis and inflammation as mechanisms therapeutic targets of Cannabis sativa in depression

Frontiers in Pharmacology
Major Depressive Disorder (MDD) is a highly prevalent and disabling psychiatric disorder, representing a major global health burden across all age groups. Increasing evidence indicates that its pathophysiology involves a complex interplay between chronic
Fernanda Pilatti, Marieli Philippsen, Amanda Gollo Bertollo, Cleneide Picinin Webler, Alessandra Kozelinski Bordignon, Zuleide Maria Ignácio   +5 more
doaj   +1 more source

Epigenetics—Innovations and Misconceptions

Natural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley   +1 more source

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20–93: The INSPIRE‐T Project

Aging Cell, Volume 24, Issue 10, October 2025.
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Wan‐Hsuan Lu, Sophie Guyonnet, Jérémy Raffin, Sandrine Bessou‐Touya, Katia Ravard Helffer, Pascale Bianchi, Jimmy Le Digabel, Paul Bensadoun, Jean‐Marc Lemaitre, Philipe de Souto Barreto, Bruno Vellas, the IHU HealthAge INSPIRE/Open Science study group, Sophie Guyonnet, Bruno Vellas, Lauréane Brigitte, Agathe Milhet, Elodie Paez, Emeline Muller, Sabine Le Floch, Catherine Takeda, Catherine Faisant, Françoise Lala, Gabor Abellan Van Kan, Zara Steinmeyer, Antoine Piau, Tony Macaron, Davide Angioni, Pierre‐Jean Ousset, Mélanie Comté, Nathalie Daniaud, Fanny Boissou‐Parachaud, Sandrine Andrieu, Christelle Cantet, Yves Rolland, Philipe de Souto Barreto, Fabien Pillard, Bernard Teysseyre, Marie Faruch, Pierre Payoux, Catherine Takeda, Neda Tavassoli, Marie Dorard, Bénédicte Razat, Camille Champigny, Sophie Guyonnet, Cédric Dray, Jean‐Philippe Pradère, Angelo Parini, Yohan Santin, Dominique Langin, Pierre Gourdy, Laurent O. Martinez, Anne Bouloumié, Angelo Parini, Nicolas Fazilleau, Roland Liblau, Jean‐Charles Guéry, Michel Simon, Nicolas Gaudenzio, Luciana Bostan, Hicham El Costa, Nabila Jabrane Ferrat, Philippe Valet, Cedric Dray, Isabelle Ader, Valérie Planat, Louis Casteilla, Pierre Payoux, Patrice Peran, Cyrille Delpierre, Sandrine Andrieu, Claire Rampon, Noelie Davezac, Bruno Guiard, Nathalie Vergnolle, Jean‐Paul Motta, Sara Djebali, Pauline Floch, Céline Deraison, Chrystelle Bonnart, Jean‐Emmanuel Sarry, Nicola Coley, Sophie Guyonnet, Christelle Cantet, Jessica Pontary, Sandrine Andrieu   +85 more
wiley   +1 more source

A Scoping Review of Neighborhood Effects and Health Among Children and Adolescents: Measurement and Design Characteristics

Journal of Community Psychology, Volume 53, Issue 4, May 2025.
ABSTRACT Decades of research have explored how neighborhood conditions relate to child and adolescent health, spawning numerous reviews focused on specific predictors, outcomes, or populations. Less is known about the design and characteristics underpinning this work.
Bria Gresham, Canan Karatekin
wiley   +1 more source

Diagnostic yield of long-read sequencing for rare diseases: a systematic review

Frontiers in Genetics
BackgroundNearly half of patients with rare genetic disorders remain undiagnosed, which may in part be due to limitations of current short-read sequencing (SRS) approaches in detecting complex genomic alterations. Long-read whole genome sequencing (lrWGS)
Amal Abdulsalam Ibrahim, Khalid A. Fakhro, Khalid A. Fakhro, Khalid A. Fakhro, Atiyeh M. Abdallah   +4 more
doaj   +1 more source

Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development

Molecular Reproduction and Development, Volume 92, Issue 5, May 2025.
ABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Indrashis Bhattacharya, Lakshmi K. Nalinan, K. V. Anusree, Ahmed Saleel, Aditi Khamamkar, Souvik Dey   +5 more
wiley   +1 more source

Effects of valproic acid on wound healing of the abdominal wall musculoaponeurotic layer: an experimental study in rats

Revista do Colégio Brasileiro de Cirurgiões
Introduction: valproic acid (VPA), an epigenetic drug, has potential for the treatment of neoplasms. Its effects on the healing of the peritoneal-musculo-aponeurotic plane (PMA) of the abdominal wall are studied.
RACHEL BIONDO SIMÕES, MARIA DE LOURDES PESSOLE BIONDO SIMÕES, SÉRGIO OSSAMU IOSHII, ROGÉRIO RIBEIRO ROBES, MOACIR OLIVEIRA DALL’ANTONIA, MATHEUS PRINCE GOEHR, PEDRO JUAN FURTADO NEVES   +6 more
doaj   +2 more sources