Results 31 to 40 of about 35,955 (167)

Factors and mechanisms of productive secondary reservoirs formation in deep-lying oil and gas complexes. Article 1. Tectonophysical mechanisms of Lower Carboniferous quartzite-sandstones decompaction in the central part of the Dniprovsko-Donetska depression at the depths of more than 4.5 km

open access: yesМінеральні ресурси України
In the world, the scale of development of secondary reservoirs in decompaction rock bodies in a wide formation range is steadily increasing: from the crystalline basement of different ages of various oil and gas-bearing basins to terrigenous deposits ...
O. Yu. Lukin, I. P. Gafych, Ya. V. Lukin
doaj   +1 more source

Crossovers between epigenesis and epigenetics. A multicenter approach to the history of epigenetics (1901-1975) [PDF]

open access: yes, 2014
The origin of epigenetics has been traditionally traced back to Conrad Hal Waddington's foundational work in 1940s. The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach.
Costa, R., Frezza, G.
core  

A Systematic Review of Adverse Childhood Experiences and Epigenetic Age Acceleration in Later Adult Life Measured With Second and Third‐Generation Epigenetic Clocks

open access: yesAmerican Journal of Medical Genetics Part B: Neuropsychiatric Genetics, Volume 201, Issue 4, Page 270-290, June 2026.
ABSTRACT We examined the relationship between adverse childhood experiences (ACEs) and epigenetic age acceleration (EAA) in adulthood as measured by second and third generation epigenetic clocks by performing a systematic review of the literature. The electronic databases MEDLINE and EMBASE were searched on 17 July 2023.
Matthew Green   +2 more
wiley   +1 more source

Developmental Systems Theory as a Process Theory [PDF]

open access: yes, 2018
Griffiths and Russell D. Gray (1994, 1997, 2001) have argued that the fundamental unit of analysis in developmental systems theory should be a process – the life cycle – and not a set of developmental resources and interactions between those resources ...
Griffiths, Paul Edmund, Stotz, Karola
core  

Social epigenetics: a science of social science? [PDF]

open access: yes, 2016
Epigenetics has considerable potential to transform social science by embedding mutually regulative reciprocal connections between biological and social processes within the human activities it studies. This paper highlights common epigenetic methods and
Bagot   +40 more
core   +3 more sources

Epigenetics—Innovations and Misconceptions

open access: yesNatural Sciences, Volume 6, Issue 2, April 2026.
ABSTRACT Epigenetics is a scientific field whose definition has changed over time. Established in the 1940s by C.H. Waddington by synthesis from embryology and genetics, the term “epigenetics” is now mainly used to describe the role of chromatin modifications in the regulation and perpetuation of gene activity states.
Bernhard Horsthemke
wiley   +1 more source

A Conceptual Approach to Complex Model Management with Generalized Modelling Patterns and Evolutionary Identification

open access: yes, 2018
Complex systems' modeling and simulation are powerful ways to investigate a multitude of natural phenomena providing extended knowledge on their structure and behavior.
Bochenina, Klavdiya O.   +7 more
core   +1 more source

Associations of Skin Biomechanical Properties With Biological Aging Clocks and Longitudinal Changes in Intrinsic Capacity in Adults Aged 20–93: The INSPIRE‐T Project

open access: yesAging Cell, Volume 24, Issue 10, October 2025.
This study assessed skin biomechanics using the Cutometer in 441 community‐dwelling adults aged 20–93 from the INSPIRE‐T cohort. We demonstrated that skin elasticity and viscoelasticity parameters were associated with the intrinsic capacity (IC) score, a functional marker of healthy aging encompassing cognition, locomotion, psychology, vitality, and ...
Wan‐Hsuan Lu   +85 more
wiley   +1 more source

Effects of valproic acid on wound healing of the abdominal wall musculoaponeurotic layer: an experimental study in rats

open access: yesRevista do Colégio Brasileiro de Cirurgiões
Introduction: valproic acid (VPA), an epigenetic drug, has potential for the treatment of neoplasms. Its effects on the healing of the peritoneal-musculo-aponeurotic plane (PMA) of the abdominal wall are studied.
RACHEL BIONDO SIMÕES   +6 more
doaj   +2 more sources

Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan

open access: yesFrontiers in Genetics, 2016
Caloric restriction (CR), defined as decreased nutrient intake without causing malnutrition, has been documented to increase both health and lifespan across numerous organisms, including humans.
Zoe E. Gillespie   +3 more
doaj   +1 more source

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