Results 21 to 30 of about 35,955 (167)

The modern versus extended evolutionary synthesis : sketch of an intra-genomic gene's eye view for the evolutionary-genetic underpinning of epigenetic and developmental evolution [PDF]

, 2018
Studying the phenotypic evolution of organisms in terms of populations of genes and genotypes, the Modern Synthesis (MS) conceptualizes biological evolution in terms of 'inter-organismal' interactions among genes sitting in the different individual ...
Blancke, Stefaan, Braeckman, Johan, De Tiège, Alexis   +2 more
core   +3 more sources

Quercetin as an Emerging Anti-Melanoma Agent: A four-focus area therapeutic development strategy

Frontiers in Nutrition, 2016
Replacing current refractory treatments for melanoma with new prevention and therapeutic approaches is crucial in order to successfully treat this aggressive cancer form. Melanoma develops from neural crest cells, which express tyrosinase -- a key enzyme
Zoey Harris, Micah G. Donovan, Gisele Morais Branco, Kirsten Limesand, Randy Burd   +4 more
doaj   +1 more source

Juvenile methylphenidate reduces prefrontal cortex plasticity via D3 receptor and BDNF in adulthood

Frontiers in Synaptic Neuroscience, 2014
Background: Early drug intervention in childhood disorders aims to maximize individual potential in the short- and long-term. Consistently, juvenile exposure to psychostimulants, such as methylphenidate (MPH), reduces risk for substance use in animals ...
Susan L Andersen, Kai Christian Sonntag
doaj   +1 more source

Genes in the postgenomic era [PDF]

, 2006
We outline three very different concepts of the gene - 'instrumental', 'nominal', and 'postgenomic'. The instrumental gene has a critical role in the construction and interpretation of experiments in which the relationship between genotype and phenotype ...
B. Alberts, B. Alberts, C. Finta, C. Kenneth Waters, C. Kenneth Waters, C. Kenneth Waters, D. Communi, D. Kampa, E.M. Neumann-Held, Frederic L. Holmes, G. Stent, George C Williams, Karola Stotz, Karola Stotz, Karola Stotz, Kim Sterelny, Lenny Moss, M Burian Richard, M.W Gray, Marcel Weber, Michael Morange, Michael R Dietrich, Michael R Dietrich, Niall Dillon, P. Kapranov, P.S.R. Coelho, Paul E. Griffiths, Pavel V. Baranov, Petter Portin, Raphael Falk, Raphael Falk, Richard Dawkins, Richard Dawkins, Robert C Olby, T. Blumenthal, Thomas Hunt Morgan, Thomas Kuhn, Thomas. Fogle, Y. Chapdelaine   +38 more
core   +2 more sources

Extending Epigenesis: From Phenotypic Plasticity to the Bio-Cultural Feedback [PDF]

, 2017
The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms.
A Bouaïchi, A Pascual-Leone, A Petronis, A Probst, A Wagner, AD Goldberg, AP Moczek, B Draganski, B Draganski, B Draganski, B Hrvoj-Mihic, C Dupont, CD Allis, CD Schlichting, CH Darwin, CH Darwin, CH Waddington, CH Waddington, CH Waddington, D Amati, D Bickerton, D Stout, D Stout, D Vazquez-Sanroman, DH Ho, DJ Bolger, DJ Cove, E Jablonka, E Jablonka, E Jablonka, E Saló, EE Hecht, EJ Richards, F Calabrese, F Lui, F Lyco, F Vinckier, G Auletta, G Auletta, G Auletta, G Fusco, G Jobard, G Manzi, G Schlosser, G Tononi, GB Müller, GH Tang, GM Edelman, H Gintis, H Ishibashi, H Vries de, I Colagè, I Colagè, I Colagè, I Colagè, I Colagè, ICG Weaver, ICG Weaver, II Schmalhausen, Ivan Colagè, J Caspers, J Masel, J Sapp, J Sapp, J Varrela, J Varrela, J-P Changeux, JD Yeatman, JK Rilling, JM Whitacre, JP Collins, JW Lewis, K Schick, K Woollett, KD Walton, KN Laland, L Caspers, L Cohen, L Daxinger, L Reich, LV Hooper, LV Hooper, M Heiser, M Iacoboni, M Iacoboni, M Kirschner, M Pigliucci, M Ptashne, M Sato, M Somel, M Szwed, M Thiebaut de Schotten, M Vigneau, MH Johnson, MH Johnson, MJ West-Eberhard, ML Anderson, ML Anderson, ML Anderson, ML Anderson, P D’Ambrosio, P Hammerstein, Paolo D’Ambrosio, PF Ferrari, PH Mason, PS Murray, R Amundson, R Gaillard, R Liebers, RA Waterland, RM Burian, RS Corruccini, S Crawford-Young, S Dehaene, S Dehaene, S Dehaene, S Hihara, S Oyama, SE Sultan, SF Gilbert, SF Gilbert, SF Gilbert, SF Gilbert, SJ Gould, SJ Gould, SJ Gould, SK Mazmanian, SM Rogers, T Adell, TJH Morgan, W Arthur, WC Wimsatt, WW Burggren, Z Petanjek, ZM Saygin   +134 more
core   +1 more source

Genome-wide DNA methylation and long-term ambient air pollution exposure in Korean adults

Clinical Epigenetics, 2019
Background Ambient air pollution is associated with numerous adverse health outcomes, but the underlying mechanisms are not well understood; epigenetic effects including altered DNA methylation could play a role. To evaluate associations of long-term air
Mi Kyeong Lee, Cheng-Jian Xu, Megan U. Carnes, Cody E. Nichols, James M. Ward, The BIOS consortium, Sung Ok Kwon, Sun-Young Kim, Woo Jin Kim, Stephanie J. London   +9 more
doaj   +1 more source

A network analysis of crab metamorphosis and the hypothesis of development as a process of unfolding of an intensive complexity

Scientific Reports, 2021
Development has intrigued humanity since ancient times. Today, the main paradigm in developmental biology and evolutionary developmental biology (evo-devo) is the genetic program, in which development is explained by the interplay and interaction of ...
Agustín Ostachuk
doaj   +1 more source

Relationship between the expression level of microRNA and the features of clinical course of the gallbladder and Оddi's sphincter functional disorders in children

Zaporožskij Medicinskij Žurnal, 2019
The aim of the work is to establish the relationship between the expression levels of microRNA-378f, microRNA-4311, microRNA-4714-3p and anamnestic, clinical and paraclinical parameters of functional disorders of the gallbladder and Oddi's sphincter (FD ...
O. Ye. Abaturov, V. L. Babуch
doaj   +1 more source

Stephane Leduc and the vital exception in the Life Sciences

, 2016
Embryogenesis, the process by which an organism forms and develops, has long been and still is a major field of investigation in the natural sciences.
Clement, Raphael
core   +2 more sources

Biological Information, Causality and Specificity - an Intimate Relationship [PDF]

, 2017
In this chapter we examine the relationship between biological information, the key biological concept of specificity, and recent philosophical work on causation.
Griffiths, Paul E., Stotz, Karola
core   +2 more sources