Results 11 to 20 of about 35,955 (167)
NeuroprotectionParkinson's disease (PD) is a chronic, progressive neurodegenerative disorder. No disease‐modifying therapies exist. This review proposes that PD susceptibility begins with epigenetic changes and neuroimmune activity—factors that alter gene expression ...
Ayodeji Johnson Ajibare +2 more
doaj +2 more sources
Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics. [PDF]
J Immunol ResBackground Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregulation in severe disease. Methods This study analyzed interleukin‐7 (IL‐7), IL‐8, and IL‐10 promoter methylation in 145 COVID‐19 ...
Yulugkural Z +4 more
europepmc +2 more sources
Patterns of Reliability: Assessing the Reproducibility and Integrity of DNA Methylation Measurement
Patterns, 2020 Summary: DNA methylation plays an important role in both normal human development and risk of disease. The most utilized method of assessing DNA methylation uses BeadChips, generating an epigenome-wide “snapshot” of >450,000 observations (probe ...
Karen Sugden +15 more
doaj +1 more source
Epigenetic regulation in lung cancer
MedComm, Volume 4, Issue 6, December 2023., 2023 Role of epigenetics in lung cancer. Epigenetics is considered the main cause of lung cancer. Epigenetics is categorized into three phenomena: histone modification, DNA methylation, and noncoding RNAs. One of the main approaches to controlling lung cancer is early diagnosis.
Shahin Ramazi +3 more
wiley +1 more source
Evolutionary ecology of the North Atlantic Talitridae (Crustacea, Amphipoda): A review [PDF]
Zoosystematics and EvolutionFour primary estuarine/marine ecotopes recognized in the North Atlantic continental littoral and continental terrestrial margins give rise to the following ecotypes: wrack generalists (=beach-hoppers), psammophilic talitrids (=sandburrowing-hoppers ...
David J. Wildish
doaj +3 more sources
Ageing And Cancer As Diseases Of Epigenesis [PDF]
, 2009 Cancer and ageing are often said to be diseases of development. During the past fifty years, the genetic components of cancer and ageing have been intensely investigated since development, itself, was seen to be an epiphenomenon of the genome.
Gilbert, Scott F.
core +2 more sources
Ethology, Volume 129, Issue 10, Page 515-526, October 2023., 2023 Our study in Tenebrio molitor employed behavioral and proteomic analyses to establish a correlation between female mate choice and molecular changes in the female brain. We found that females preferred mating with more attractive males, who in turn had a greater likelihood of successfully mating and producing more larvae with attractive males than with
Miguel Hernández‐Villanueva +3 more
wiley +1 more source
Oman Medical Journal, 2020 Objectives: Chronic lymphocytic leukemia (CLL) is characterized by the accumulation of apparently mature B-type lymphocytes in the lymphohematopoietic organs.
Morteza Hashemi +3 more
doaj +1 more source
Epigenetics: What it is about? [PDF]
, 2014 Epigenetics has captured the attention of scientists in the past decades, yet its scope has been continuously changing. In this paper, we give an overview on how and why its definition has evolved and suggest several clarification on the concepts used in
Ogryzko, Vasily, Saade, Evelyne
core +3 more sources
Epigenetic DNA changes and stem cells therapy [PDF]
Archive of Oncology, 2013 We are starting to understand the fundamental biological processes which underlie the DNA physical properties. Of particular importance is the field of epigenetics, which literally means 'outside conventional genetics', now used to describe the study ...
Stupar Milanko +4 more
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