Results 11 to 20 of about 40,544 (241)
NeuroprotectionParkinson's disease (PD) is a chronic, progressive neurodegenerative disorder. No disease‐modifying therapies exist. This review proposes that PD susceptibility begins with epigenetic changes and neuroimmune activity—factors that alter gene expression ...
Ayodeji Johnson Ajibare +2 more
doaj +2 more sources
Epigenetic Modulation of IL-7 and IL-10: Toward Personalized Immune Therapies in Viral Epidemics. [PDF]
J Immunol ResBackground Host immune responses, including cytokine production, shape the severity of viral epidemics. Epigenetic mechanisms such as DNA methylation regulate cytokine gene expression and may contribute to immune dysregulation in severe disease. Methods This study analyzed interleukin‐7 (IL‐7), IL‐8, and IL‐10 promoter methylation in 145 COVID‐19 ...
Yulugkural Z +4 more
europepmc +2 more sources
Evolving Lessons on Metazoan Primordial Germ Cells in Diversity and Development. [PDF]
Mol Reprod DevABSTRACT Germ cells are pivotal for the continuation of biological species. The metazoan germline develops from primordial germ cells (PGCs) that undergo multiple rounds of mitotic divisions. The PGCs are specified by either maternal inheritance of asymmetrically polarized cytoplasmic mRNAs/proteins (found in roundworms, flies, fishes, frogs, and fowl)
Bhattacharya I +5 more
europepmc +2 more sources
Extending epigenesis: from phenotypic plasticity to the bio-cultural feedback [PDF]
, 2017 The paper aims at proposing an extended notion of epigenesis acknowledging an actual causal import to the phenotypic dimension for the evolutionary diversification of life forms.
P. D'Ambrosio, I. Colagè
semanticscholar +3 more sources
Sats: northern european journal of philosophy, 2023 In the 1787 Transcendental Deduction of the Categories Kant indicates the only possible ways by which one can account for a necessary agreement of experience with the concepts of its objects (B166), using analogies between modes of explanation and ...
C. Ferrini
semanticscholar +1 more source
Kant’s views on preformation and epigenesis
Kant e-Prints, 2023 How does Kant repsond to the early modern preformation-epigenesis controversy? In part 1 of the paper, I will introduce the historical context: I provide an overview of important systematic characteristics of ovistic and animalculist preformationist (1.1)
Ina Goy
semanticscholar +1 more source
International Journal of Molecular Sciences, 2022 Medically assisted reproduction, now considered a routine, successful treatment for infertility worldwide, has produced at least 8 million live births. However, a growing body of evidence is pointing toward an increased incidence of epigenetic/imprinting
Y. Menezo +4 more
semanticscholar +1 more source
Perspectivas em medicina legal e pericias medicas, 2022 Introduction: This article aims to address the topic of doctrinal expert medicine in a biopsychosocial epistemological study of the concepts of epigenesis and epigenetics from a perspective that contemplates the biological, psychic and social approaches,
Jose Jozefran Berto Freire
semanticscholar +1 more source
Contradiction That Never Was: Epigenesis versus Modularity in Evolutionary Aesthetics
Aisthesis. Pratiche, linguaggi e saperi dell’estetico, 2022 Coevolutionary aesthetics has been forming since the early 2010s. Its contribution of great value has been the inclusion of cultural evolution into Darwinian theories on the origins of art and aesthetic judgement.
Onerva Kiianlinna
semanticscholar +1 more source
Epigenetic and genetic approach to the transmissibility of dental characteristics in twins: Report of two cases [PDF]
Stomatološki glasnik Srbije, 2011 Transmissibility of dental and jaw characteristics is strongly influenced by environmental factors during the years of extra uterine life when odontogenesis occurs.
Jefferson Martins Ronald +4 more
doaj +1 more source