Results 21 to 30 of about 625,174 (305)
Genetic, environmental and stochastic factors in monozygotic twin discordance with a focus on epigenetic differences [PDF]
, 2012 Genetic-epidemiological studies on monozygotic (MZ) twins have been used for decades to tease out the relative contributions of genes and the environment to a trait.
Morahan, JM +13 more
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Epigenetics and depression [PDF]
Dialogues in Clinical Neuroscience, 2019 The risk for major depression is both genetically and environmentally determined. It has been proposed that epigenetic mechanisms could mediate the lasting increases in depression risk following exposure to adverse life events and provide a mechanistic framework within which genetic and environmental factors can be integrated.
Penner-Goeke, S. +1 more
openaire +3 more sources
Immuno-Epigenetic Markers for Infectious Diseases
, 2020 This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject.
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Role of histone methylation in paternal transmission of epigenetic information [PDF]
, 2010 During the development of multi-cellular organisms, one genome gives rise to multiple differentiated cell types. This is achieved by sequence specific transcription factors and different epigenetic mechanisms, which collaborate in reading the genetic ...
Brykczynska, Urszula
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Epigenetic Target Profiler: A Web Server to Predict Epigenetic Targets of Small Molecules [PDF]
, 2021 Motivation: The identification of protein targets of small molecules is essential for drug discovery. With the increasing amount of chemogenomic data in the public domain, multiple ligand-based models for target prediction have emerged.
Jose L., Medina-Franco +1 more
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The Epigenetic Cytocrin Pathway to the Nucleus. Epigenetic Factors, Epigenetic Mediators, and Epigenetic Traits. A Biochemist Perspective [PDF]
Frontiers in Genetics, 2017 A single word, Epigenetics, underlies one exciting subject in today's Science, with different sides and with interactions with philosophy. The apparent trivial description includes everything in between genotype and phenotype that occurs for a given unique DNA sequence/genome.
Gemma Navarro +5 more
openaire +5 more sources
Nature Communications, 2021 In animal embryos, maternally deposited mRNAs are degraded by several different mechanisms. Here the authors show that C. elegans embryos inherit antisense pool of small RNAs which are loaded into CSR-1 and cleave complementary maternal mRNAs.
Piergiuseppe Quarato +7 more
doaj +1 more source
Epigenetic Regulation and Measurement of Epigenetic Changes [PDF]
Biological Research For Nursing, 2012 Epigenetic mechanisms provide an adaptive layer of control in the regulation of gene expression that enables an organism to adjust to a changing environment. Epigenetic regulation increases the functional complexity of deoxyribonucleic acid (DNA) by altering chromatin structure, nuclear organization, and transcript stability.
Stephens, Kimberly E +4 more
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Basics of Epigenetics and Role of Epigenetics in Diabetic Complications
Journal of Pharmacy and Bioallied Sciences, 2021 The term “Epigenetics” includes mechanisms by which genetic expression is altered without a change in the underlying DNA sequence. The changes caused by epigenetic mechanisms are inheritable and are one way in direction (irreversible) and also explains why there is differences in genetic expressions of monozygotic twins. The epigenetic mechanisms alter
Andamuthu Yamunadevi +4 more
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Epigenetics and sarcoidosis [PDF]
European Respiratory Review, 2021 Epigenetic modifications are emerging as important regulatory mechanisms of gene expression in lung disease, given that they are influenced by environmental exposures and genetic variants, and that they regulate immune and fibrotic processes. In this review, we introduce these concepts with a focus on the study of DNA methylation and histone ...
Konigsberg, Iain R. +2 more
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