Results 81 to 90 of about 865,085 (290)

Introduction: The Third International Conference on Epigenetic Robotics [PDF]

, 2003
This paper summarizes the paper and poster contributions to the Third International Workshop on Epigenetic Robotics. The focus of this workshop is on the cross-disciplinary interaction of developmental psychology and robotics. Namely, the general goal in
Berthouze, Luc, Prince, Christopher G.
core  

Syngenetic sand veins and anti-syngenetic sand wedges, Tuktoyaktuk Coastlands, western Arctic Canada [PDF]

, 2007
Sand-sheet deposits of full-glacial age in the Tuktoyaktuk Coastlands, western Arctic Canada, contain syngenetic sand veins 1-21 cm wide and sometimes exceeding 9 m in height.
Bateman, Bateman, Berg, Brookfield, Burn, Carter, Carter, Dallimore, Dinter, Dostovalov, Dylik, Environment Canada, French, French, Ghysels, Gozdzik, Harry, Hopkins, Julian B. Murton, Kasper, Kasse, Kocurek, Kolstrup, Kolstrup, Kolstrup, Kolstrup, Koster, Koster, Koster, Lea, Lea, Lea, Lewkowicz, MacDonald, Mackay, Mackay, Mackay, Mackay, Mackay, Mackay, Mackay, Mackay, Mark D. Bateman, Melnikov, Murton, Murton, Murton, Péwé, Rampton, Ritchie, Sher, Sletten, Taylor, Van der Hammen, Vandenberghe, Vasil'chuk, Worsley, Yershov   +57 more
core   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

The physics of epigenetics

, 2016
In higher organisms, all cells share the same genome, but every cell expresses only a limited and specific set of genes that defines the cell type. During cell division, not only the genome, but also the cell type is inherited by the daughter cells. This
Barbi, Maria, Caré, Bertrand R., Cortini, Ruggero, Lavelle, Christophe, Lesne, Annick, Mozziconacci, Julien, Victor, Jean-Marc   +6 more
core   +3 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

An endogenous microRNA (miRNA1166.1) can regulate photobio-H2 production in eukaryotic green alga Chlamydomonas reinhardtii

Biotechnology for Biofuels, 2018
Background Hydrogen photoproduction from green microalgae is regarded as a promising alternative solution for energy problems. However, the simultaneous oxygen evolution from microalgae can prevent continuous hydrogen production due to the ...
Yuting Wang, Xiaoshan Zhuang, Meirong Chen, Zhiyong Zeng, Xiaoqi Cai, Hui Li, Zhangli Hu   +6 more
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

It's the fiber, not the fat: significant effects of dietary challenge on the gut microbiome

Microbiome, 2020
Background Dietary effects on the gut microbiome play key roles in the pathophysiology of inflammatory disorders, metabolic syndrome, obesity, and behavioral dysregulation.
Kathleen E. Morrison, Eldin Jašarević, Christopher D. Howard, Tracy L. Bale   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Molecular effect of ethanol during neural differentiation of human embryonic stem cells in vitro

Genomics Data, 2014
Potential teratogenic effects of alcohol on fetal development have been documented. Especially studies have demonstrated deleterious effect of ethanol exposure on neuronal development in animal models and on the maintenance and differentiation of ...
Jeffrey J. Kim, Lewei Duan, Thanh G. Tu, Omid Elie, Yiyoung Kim, Nathan Mathiyakom, David Elashoff, Yong Kim   +7 more
doaj   +1 more source