Results 141 to 150 of about 14,860 (271)
EXPLORING EPIGENETIC CLOCKS AND COGNITIVE CHANGE IN MIDDLE ADULTHOOD [PDF]
Daisy Zavala +6 more
openalex +1 more source
Genome‐Wide by Lifetime Environment Interaction Studies of Brain Imaging Phenotypes
Advanced Science, EarlyView.This study explores genome‐wide by lifetime environment interactions on brain imaging phenotypes. Gene‐environment interactions explain more phenotypic variance than main effects, pinpoint regulatory variants, and reveal exposure‐specific biological pathways.
Sijia Wang +51 more
wiley +1 more source
Longitudinal changes in epigenetic clocks predict survival in the InCHIANTI cohort [PDF]
Pei‐Lun Kuo +7 more
openalex +1 more source
Blood and skeletal muscle ageing determined by epigenetic clocks and their associations with physical activity and functioning [PDF]
, 2021 Elina Sillanpää +11 more
openalex +1 more source
Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS
Advanced Science, EarlyView.This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu +14 more
wiley +1 more source
Additional file 2: of Correlation of an epigenetic mitotic clock with cancer risk
, 2016 Zhen Yang +9 more
openalex +1 more source
Advanced Science, EarlyView.Spermatogonial stem cells (SSCs) provide critical support to spermatogenesis. Here, the author established Il1r2 as a sorting marker for SSCs, with which further insights into the SSC heterogeneity and dynamic features can be obtained. They also confirmed findings in both mouse and human, thus validating IL1R2 as the surface marker for isolating and ...
Pengyu Li +19 more
wiley +1 more source
Transfer Elastic Net for Developing Epigenetic Clocks for the Japanese Population [PDF]
Yui Tomo, Ryo Nakaki
openalex +1 more source
Epigenetic clocks are not accelerated in COVID-19 patients [PDF]
, 2020 Julia Franzen +12 more
openalex +1 more source
Advanced Science, EarlyView.In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong +11 more
wiley +1 more source