Results 161 to 170 of about 14,860 (271)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

Advanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang, Lihuan Shang, Xiaochun Chen, Xiangzhan Kong, Xiaojuan Wang, Linjia Jiang, Huiying Zhao, Yafeng Zhu, Cheng Huang, Shiyi Deng, Rui Zhang, Minghui Wang, Haoming Lin, Ping‐Pui Wong   +13 more
wiley   +1 more source

An ELOVL2-Based Epigenetic Clock for Forensic Age Prediction: A Systematic Review. [PDF]

Int J Mol Sci, 2023
Paparazzo E, Lagani V, Geracitano S, Citrigno L, Aceto MA, Malvaso A, Bruno F, Passarino G, Montesanto A.   +8 more
europepmc   +1 more source

Dental Ageing Offers New Insights Into the First Epigenetic Clock for Common Dolphins (<i>Delphinus delphis</i>). [PDF]

Ecol Evol
Hanninger EF, Peters KJ, Gerber L, Barratclough A, Betty EL, Palmer EI, Horvath S, Stockin KA.   +7 more
europepmc   +1 more source

The protein cargo of extracellular vesicles correlates with the epigenetic aging clock of exercise sensitive DNAmFitAge [PDF]

Bernadett György, Réka Szatmári, Tamás Ditrói, Ferenc Torma, Krisztina Pálóczi, Mirjam Balbisi, Tamás Visnovitz, Erika Koltai, Péter Nagy, Edit I. Buzás, Steve Horvath, Zsolt Radák   +11 more
openalex   +1 more source

Epigenetic clock work ticks forward

Nature Aging
C. P. Ryan, D. W. Belsky
openaire   +2 more sources

Epstein‐Barr Virus Expressed Long Non‐Coding RNA (lncBARTs) Regulate EBV Latent Genome Replication

Advanced Science, EarlyView.
EBV produces abundant level of lncBARTs, which are essential for maintaining viral genome replication in EBV‐associated cancers. LncBARTs interact with a complex comprising BRD4, CTCF and viral protein EBNA1 at EBV oriP region. This interaction tethers oriP to host chromosomes, facilitating EBV episome replication.
Jiayan Liu, Dittman Lai‐Shun Chung, Larry Ka‐Yue Chow, Shuo Han, Wenkai Yi, Conor J. Cremin, Yingyin Liao, Pui Wang, Bobo Wing‐Yee Mok, Mingfang Ji, Jian Yan, Wei Dai, Honglin Chen   +12 more
wiley   +1 more source

Thanatological Epigenetics as a Postmortem Forensic Tool: A Contextual Call for Epigenetic Clock Research in Asia. [PDF]

Acad Forensic Pathol
Bugaoan AJP, Lucero-Prisno DE, Aban JL.
europepmc   +1 more source

Sperm epigenetic clock associates with pregnancy outcomes in the general population. [PDF]

Hum Reprod, 2022
Pilsner JR, Saddiki H, Whitcomb BW, Suvorov A, Buck Louis GM, Mumford SL, Schisterman EF, Oluwayiose OA, Balzer LB.   +8 more
europepmc   +1 more source

Epigenetics of Homocystinuria, Hydrogen Sulfide, and Circadian Clock Ablation in Cardiovascular–Renal Disease [PDF]

Suresh C. Tyagi
openalex   +1 more source

NDST3‐Induced Epigenetic Reprogramming Reverses Neurodegeneration in Parkinson's Disease

Advanced Science, EarlyView.
NDST3‐mediated epigenetic reprogramming revitalizes neuronal circuits in the substantia nigra and striatum to halt dopaminergic neuron degeneration and restore motor function in Parkinson's disease models. This strategy promotes neuronal maintenance and functional recovery, highlighting NDST3's therapeutic potential in neurodegenerative disorders ...
Yujung Chang, Yongwoo Na, Hyeonjoo Im, Garam Yang, Seungseon Yang, Hyun Soo Shim, Chunggoo Kim, GyeungYun Kim, Hyeok Ju Park, Hee Young Kim, Seung Eun Lee, Wonwoong Lee, Yoon Ha, Sungho Park, Jieun Kim, Won‐Young Cho, Woong Sun, Jong‐Seo Kim, Junsang Yoo   +18 more
wiley   +1 more source