Results 241 to 250 of about 431,319 (321)

Characterising developmental dynamics of adult epigenetic clock sites. [PDF]

EBioMedicine
Mulder RH, Neumann A, Felix JF, Suderman M, Cecil CAM.   +4 more
europepmc   +1 more source

HIC1 suppresses Tumor Progression and Enhances CD8+ T Cells Infiltration Through Promoting GSDMD‐induced Pyroptosis in Gastric Cancer

Advanced Science, EarlyView.
These findings elucidate the innovative role of HIC1 as a transcriptional activator in GC, driving the initiation of pyroptosis and enhancing CD8+ T cell infiltration, which has certain novelty and creative significance. Collectively, targeting HIC1 can present an appealing immunotherapeutic strategy to improve outcomes in GC patients.
Mengjie Kang, Wenqi Du, Lina Ding, Mengdi Wu, Dongsheng Pei   +4 more
wiley   +1 more source

Epigenetic events influencing the biological clock: Panacea for neurodegeneration

Heliyon
The human biological clock is the 24-h internal molecular network of circadian genes in synchronization with other cells in response to external stimuli.
Indrani Paramasivan Latha Laxmi, Ramasamy Tamizhselvi   +1 more
doaj  

Epigenetic Clock Analysis for National Institutes of Health Stroke Scale in Patients With Ischemic Stroke. [PDF]

Neuropsychopharmacol Rep
Jiang W, Shirai T, Otsuka I, Okazaki S, Tanifuji T, Horai T, Minami H, Miyachi M, Okada S, Hishimoto A.   +9 more
europepmc   +1 more source

LincNEAT1 Encoded‐NEAT1‐31 Promotes Phagocytosis by Directly Activating the Aurora‐A–PI3K–AKT Pathway

Advanced Science, EarlyView.
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li, Jing Zhang, Xixi Li, Xin Liu, Bo Zeng, Jiayue Luo, Huijin Wang, Hanbing Zhang, Xinya Gao   +8 more
wiley   +1 more source

Epigenetic Clock in Bears: A Simple Cost-Effective Blood DNA Methylation-Based Age Estimation Method Applicable to Multiple Bear Species. [PDF]

Ecol Evol
Shimozuru M, Nakamura S, Yamazaki J, Yanagawa Y, Tamatani H, Kuroe M, Yamazaki K, Koike S, Goto Y, Naganuma T, Tochigi K, Inagaki A, Takekoshi N, Baek S, Sato N, Honda Y, Tsubota T, Ito H.   +17 more
europepmc   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

Correction for: EpiAge: a next-generation sequencing-based <i>ELOVL2</i> epigenetic clock for biological age assessment in saliva and blood across health and disease. [PDF]

Aging (Albany NY)
Cheishvili D, Carmo SD, Caraci F, Grasso M, Cuello AC, Szyf M.   +5 more
europepmc   +1 more source

Exploiting the Circadian Clock for Improved Cancer Therapy: Perspective From a Cell Biologist [PDF]

, 2019
Kuo, T., Ladurner, A.
core   +1 more source

Additional file 2 of Susceptibility to hormone-mediated cancer is reflected by different tick rates of the epithelial and general epigenetic clock

, 2022
James E. Barrett, Chiara Herzog, Yoo‐Na Kim, Thomas E. Bartlett, Allison Jones, Iona Evans, David Cibula, Michal Zikán, Line Bjørge, Nadia Harbeck, Nicoletta Colombo, Sacha J. Howell, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Martin Widschwendter   +14 more
openalex   +2 more sources