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What makes clocks tick? Characterizing developmental dynamics of adult epigenetic clock sites
Mulder RH +4 more
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Epigenetic clocks, aging, and cancer
Science, 2022Global methylation changes in aging cells affect cancer risk and tissue ...
Sarah E, Johnstone +3 more
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Evolutionary Anthropology: Issues, News, and Reviews, 2018
AbstractRecent research has revealed clock‐like patterns of epigenetic change across the life span in humans. Models describing these epigenetic changes have been dubbed “epigenetic clocks,” and they can not only predict chronological age but also reveal biological age, which measures physiological homeostasis and deterioration over the life span ...
Elaine E. Guevara, Richard R. Lawler
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AbstractRecent research has revealed clock‐like patterns of epigenetic change across the life span in humans. Models describing these epigenetic changes have been dubbed “epigenetic clocks,” and they can not only predict chronological age but also reveal biological age, which measures physiological homeostasis and deterioration over the life span ...
Elaine E. Guevara, Richard R. Lawler
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Epigenetic clock analysis in methamphetamine dependence
Psychiatry Research, 2022Methamphetamine (MA) is used worldwide and causes serious public health and social problems. MA affects the central nervous, cardiac, and immune systems, which causes neuropsychiatric and cardiovascular diseases and infection. Epigenetic changes, including DNA methylation (DNAm), are associated with various clinical phenotypes of MA abuse.
Yukihiro Takemura +9 more
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Science, 2023
DNA methylation can identify evolutionary relationships among close plant ...
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DNA methylation can identify evolutionary relationships among close plant ...
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Epigenetic Drift, Epigenetic Clocks and Cancer Risk
Epigenomics, 2016It is well-established that the DNA methylation landscape of normal cells undergoes a gradual modification with age, termed as 'epigenetic drift'. Here, we review the current state of knowledge of epigenetic drift and its potential role in cancer etiology.
Shijie C, Zheng +2 more
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Epigenetic Clocks: In Aging-Related and Complex Diseases
Cytogenetic and Genome Research, 2023<b><i>Background:</i></b> There is evidence that complex diseases and mortality are associated with DNA methylation and age acceleration. Numerous epigenetic clocks, including Horvath, Hannum, DNA PhenoAge, DNA GrimAge, and Dunedin Pace of Aging Methylation, continue to be developed in this young scientific field.
Margiotti, Katia +4 more
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This document describes the generation of epigenetic clocks and immune cell counts from DNA methylation data from participants of the National Longitudinal Study of Adolescent to Adult Health (Add Health). It provides detailed definitions, computation methods, data descriptions, and guidance for interpretation to ensure consistent and reproducible use ...
Levitt, Brandt +4 more
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Levitt, Brandt +4 more
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