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The Epigenetic Language of Circadian Clocks
2013Epigenetic control, which includes DNA methylation and histone modifications, leads to chromatin remodeling and regulated gene expression. Remodeling of chromatin constitutes a critical interface of transducing signals, such as light or nutrient availability, and how these are interpreted by the cell to generate permissive or silenced states for ...
Saurabh, Sahar, Paolo, Sassone-Corsi
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Epigenetic Aging Clocks in Ecology and Evolution
Trends in Ecology & Evolution, 2019The development of 'epigenetic clocks' is changing how biomedical scientists approach age-associated disease and leads to new insights and questions of wider significance. We highlight recent findings concerning epigenetic aging and discuss their relevance to life history evolution and their potential for advancing the field of ecological and ...
Benjamin B, Parrott, Emily M, Bertucci
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C&EN Global Enterprise, 2019
Epigenetic clocks use DNA methylation to measure biological age. Differences between biological age and actual chronological age can reflect health issues. Such clocks are constructed by measuring DNA methylation at multiple sites and correlating that with the known age.
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Epigenetic clocks use DNA methylation to measure biological age. Differences between biological age and actual chronological age can reflect health issues. Such clocks are constructed by measuring DNA methylation at multiple sites and correlating that with the known age.
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2017
Background: During the last decade, multiple efforts have been dedicated to the modelling of an accurate predictor of age based on DNA methylation status(1–4). However, most of current models have been trained and therefore predict over a limited typology of tissues, and consequently the application over a wider extent of tissues is restricted .
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Background: During the last decade, multiple efforts have been dedicated to the modelling of an accurate predictor of age based on DNA methylation status(1–4). However, most of current models have been trained and therefore predict over a limited typology of tissues, and consequently the application over a wider extent of tissues is restricted .
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Relationship between Epigenetics and Circadian Clock
2016The circadian clock controls the daily rhythmicity of the biochemistry, physiology, and behavior of the organisms. Disruption of circadian rhythms, affects many biological processes within the body and results in different long-term diseases, such as cancer.
KARTLAŞMIŞ, Kezban +4 more
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